Epicardial Adipose Tissue: a Potential Therapeutic Target for Cardiovascular Diseases

With increased ageing of the population, cardiovascular disease (CVD) has become the most important factor endangering human health worldwide. Although the treatment of CVD has become increasingly advanced, there are still a considerable number of patients with conditions that have not improved. According to the latest clinical guidelines of the European Cardiovascular Association, obesity has become an independent risk factor for CVD. Adipose tissue includes visceral adipose tissue and subcutaneous adipose tissue. Many previous studies have focused on subcutaneous adipose tissue, but visceral adipose tissue has been rarely studied. However, as a type of visceral adipose tissue, epicardial adipose tissue (EAT) has attracted the attention of researchers because of its unique anatomical and physiological characteristics. This review will systematically describe the physiological characteristics and evaluation methods of EAT and emphasize the important role and treatment measures of EAT in CVD.

Automated summary

With the increasing ageing population, cardiovascular disease (CVD) has become a major health threat globally. Obesity has been identified as an independent risk factor for CVD. However, the unique characteristics of epicardial adipose tissue (EAT) in visceral adipose tissue have attracted researchers' attention, requiring further research on its important role and treatment measures in CVD.