MicroRNA-146b protects kidney injury during urinary tract infections by modulating macrophage polarization

NLRP3 inflammasome is involved in the mechanism of the mitigative effect of lycopene on sulfamethoxazole-induced inflammatory damage in grass carp kidneys

(2022) Hongmin Lu et al.   FISH & SHELLFISH IMMUNOLOGY

Role of metabolism in uropathogenic Escherichia coli

(2022) Carly C.Y. Chan et al.   TRENDS IN MICROBIOLOGY

miR-21 and miR-146a: The microRNAs of inflammaging and age-related diseases

(2021) Fabiola Olivieri et al.   AGEING RESEARCH REVIEWS

Molecular determinants of disease severity in urinary tract infection

(2021) Ines Ambite et al.   Nature Reviews Urology

M1 macrophage exosomes engineered to foster M1 polarization and target the IL-4 receptor inhibit tumor growth by reprogramming tumor-associated macrophages into M1-like macrophages

(2021) Gowri Rangaswamy Gunassekaran et al.   BIOMATERIALS

Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies

(2020) Roger D. Klein et al.   NATURE REVIEWS MICROBIOLOGY

Downregulation of miR-146b-5p via iodine involvement repressed papillary thyroid carcinoma cell proliferation

(2020) Yujia Pan et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Urinary tract infections in children

(2020) Kjell Tullus et al.   LANCET

Intravenous Arginine Administration Downregulates NLRP3 Inflammasome Activity and Attenuates Acute Kidney Injury in Mice with Polymicrobial Sepsis

(2020) Sharon Angela Tanuseputero et al.   MEDIATORS OF INFLAMMATION

The immune response to infection in the bladder

(2020) Livia Lacerda Mariano et al.   Nature Reviews Urology

Therapeutic silencing miR-146b-5p improves cardiac remodeling in a porcine model of myocardial infarction by modulating the wound reparative phenotype

(2020) Yiteng Liao et al.   Protein & Cell

Colorectal cancer prompted adipose tissue browning and cancer cachexia through transferring exosomal miR‐146b‐5p

(2020) Wenjuan Di et al.   JOURNAL OF CELLULAR PHYSIOLOGY

UropathogenicEscherichia coliemploys both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination

(2019) Claudia J. Stocks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The circINTS4/miR-146b/CARMA3 axis promotes tumorigenesis in bladder cancer

(2019) Xiaotong Zhang et al.   CANCER GENE THERAPY

Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages

(2019) Marco Orecchioni et al.   Frontiers in Immunology

Severe Fever With Thrombocytopenia Syndrome Virus-Induced Macrophage Differentiation Is Regulated by miR-146

(2019) Li Zhang et al.   Frontiers in Immunology

MiR-146b accelerates osteoarthritis progression by targeting alpha-2-macroglobulin

(2019) Xin Liu et al.   Aging-US

Identification of a miR-146b-FasL axis in the development of neutropenia in T large granular lymphocyte leukemia

(2019) Barbara Mariotti et al.   HAEMATOLOGICA

miR-146b-5p has a sex-specific role in renal and cardiac pathology in a rat model of chronic kidney disease

(2019) Mark R. Paterson et al.   KIDNEY INTERNATIONAL

Forced expression of microRNA-146b reduces TRAF6-dependent inflammation and improves ischemia-induced neovascularization in hypercholesterolemic conditions

(2019) Michel Desjarlais et al.   ATHEROSCLEROSIS

Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury

(2019) Changying Wang et al.   Mucosal Immunology

A hispanolone-derived diterpenoid inhibits M2-Macrophage polarization in vitro via JAK/STAT and attenuates chitin induced inflammation in vivo

(2018) Lidia Jiménez-García et al.   BIOCHEMICAL PHARMACOLOGY

MicroRNA-146b-3p promotes cell metastasis by directly targeting NF2 in human papillary thyroid cancer

(2018) Chunxiao Yu et al.   THYROID

Cytotoxic Necrotizing Factor 1 Downregulates CD36 Transcription in Macrophages to Induce Inflammation During Acute Urinary Tract Infections

(2018) Huan Yang et al.   Frontiers in Immunology

A Molecular Targeted Immunotherapeutic Strategy for Ulcerative Colitis via Dual-Targeting Nanoparticles Delivering miR-146b to Intestinal Macrophages

(2018) Feihong Deng et al.   Journal of Crohns & Colitis

miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer

(2018) Meina Yan et al.   Cell Death & Disease

miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis

(2017) Helen Hermann et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

miR-146b-5p suppresses glioblastoma cell resistance to temozolomide through targeting TRAF6

(2017) Zhongrun Qian et al.   ONCOLOGY REPORTS

Acute Kidney Injury in Pregnancy

(2017) Belinda Jim et al.   SEMINARS IN NEPHROLOGY

Stromal Cell-Derived Factor 1 Mediates Immune Cell Attraction upon Urinary Tract Infection

(2017) Batya Isaacson et al.   Cell Reports

Trichoderma asperelloides Spores Downregulate dectin1/2 and TLR2 Receptors of Mice Macrophages and Decrease Candida parapsilosis Phagocytosis Independent of the M1/M2 Polarization

(2017) Andréa G. dos Santos et al.   Frontiers in Microbiology

The complement factor 5a receptor 1 has a pathogenic role in chronic inflammation and renal fibrosis in a murine model of chronic pyelonephritis

(2016) Naheed Choudhry et al.   KIDNEY INTERNATIONAL

Metabolic Requirements of Escherichia coli in Intracellular Bacterial Communities during Urinary Tract Infection Pathogenesis

(2016) Matt S. Conover et al.   mBio

Reprogramming macrophage orientation by microRNA 146b targeting transcription factor IRF5

(2016) Liang Peng et al.   EBioMedicine

MicroR-146 blocks the activation of M1 macrophage by targeting signal transducer and activator of transcription 1 in hepatic schistosomiasis

(2016) Xing He et al.   EBioMedicine

Macrophages: Development and Tissue Specialization

(2015) Chen Varol et al.   Annual Review of Immunology

Macrophages Subvert Adaptive Immunity to Urinary Tract Infection

(2015) Gabriela Mora-Bau et al.   PLoS Pathogens

Crosstalk between Sentinel and Helper Macrophages Permits Neutrophil Migration into Infected Uroepithelium

(2014) Marzena Schiwon et al.   CELL

Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b

(2013) G. Curtale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-181a, -146a and -146b in spleen CD4+ T lymphocytes play proinflammatory roles in a murine model of asthma

(2012) Meng-Jie Feng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY