Mining the ZINC database of natural products for specific, testosterone-like, OXER1 antagonists
出版年份 2023 全文链接
标题
Mining the ZINC database of natural products for specific, testosterone-like, OXER1 antagonists
作者
关键词
-
出版物
STEROIDS
Volume 199, Issue -, Pages 109309
出版商
Elsevier BV
发表日期
2023-09-10
DOI
10.1016/j.steroids.2023.109309
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mint3 as a Potential Target for Cooling Down HIF-1α-Mediated Inflammation and Cancer Aggressiveness
- (2023) Noritaka Tanaka et al. Biomedicines
- Steroid Hormone Receptors: Links With Cell Cycle Machinery and Breast Cancer Progression
- (2021) Suryendu Saha et al. Frontiers in Oncology
- GalaxyWater-wKGB: Prediction of Water Positions on Protein Structure Using wKGB Statistical Potential
- (2021) Lim Heo et al. Journal of Chemical Information and Modeling
- Eicosanoid receptors as therapeutic targets for asthma
- (2021) William S. Powell CLINICAL SCIENCE
- Enhanced OXER1 expression is indispensable for human cancer cell migration
- (2021) Konstantina Kalyvianaki et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Targeting the OXE receptor with a selective antagonist inhibits allergen‐induced pulmonary inflammation in non‐human primates
- (2021) Chantal Cossette et al. BRITISH JOURNAL OF PHARMACOLOGY
- OXER1 mediates testosterone-induced calcium responses in prostate cancer cells
- (2021) Athanasios A. Panagiotopoulos et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- New Antagonists of the Membrane Androgen Receptor OXER1 from the ZINC Natural Product Database
- (2021) Athanasios A. Panagiotopoulos et al. ACS Omega
- Pharmacological inhibition of Mint3 attenuates tumour growth, metastasis, and endotoxic shock
- (2021) Takeharu Sakamoto et al. Communications Biology
- Improved protein structure prediction using potentials from deep learning
- (2020) Andrew W. Senior et al. NATURE
- Targeting the OXE receptor as a potential novel therapy for asthma
- (2020) William S. Powell et al. BIOCHEMICAL PHARMACOLOGY
- A simple open source bioinformatic methodology for initial exploration of GPCR ligands’ agonistic/antagonistic properties
- (2020) Athanasios A. Panagiotopoulos et al. Pharmacology Research & Perspectives
- Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects
- (2020) Ya-Wen Cheng et al. Cell Reports
- OXER1 and RACK1-associated pathway: a promising drug target for breast cancer progression
- (2020) Mirco Masi et al. Oncogenesis
- Membrane androgen receptors (OXER1, GPRC6A AND ZIP9) in prostate and breast cancer: A comparative study of their expression
- (2019) Konstantina Kalyvianaki et al. STEROIDS
- Protein structure prediction using multiple deep neural networks in the 13th Critical Assessment of Protein Structure Prediction (CASP13)
- (2019) Andrew W. Senior et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists
- (2018) Tomasz Maciej Stepniewski et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Arachidonic acid: Physiological roles and potential health benefits – A review
- (2018) Hatem Tallima et al. Journal of Advanced Research
- Antagonizing effects of membrane-acting androgens on the eicosanoid receptor OXER1 in prostate cancer
- (2017) Konstantina Kalyvianaki et al. Scientific Reports
- SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
- (2017) Antoine Daina et al. Scientific Reports
- Dual Roles of Group IID Phospholipase A2in Inflammation and Cancer
- (2016) Yoshimi Miki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Galaxy7TM: flexible GPCR–ligand docking by structure refinement
- (2016) Gyu Rie Lee et al. NUCLEIC ACIDS RESEARCH
- Spherical polar Fourier assembly of protein complexes with arbitrary point group symmetry
- (2016) David W. Ritchie et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- ZINC 15 – Ligand Discovery for Everyone
- (2015) Teague Sterling et al. Journal of Chemical Information and Modeling
- Effective protein model structure refinement by loop modeling and overall relaxation
- (2015) Gyu Rie Lee et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- A Small-Molecule Furin Inhibitor Inhibits Cancer Cell Motility and Invasiveness
- (2015) Julia M. Coppola et al. NEOPLASIA
- Design and synthesis of 21-alkynylaryl pregnenolone derivatives and evaluation of their anticancer activity
- (2014) György Szalóki et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Identification and Characterization of Membrane Androgen Receptors in the ZIP9 Zinc Transporter Subfamily: II. Role of Human ZIP9 in Testosterone-Induced Prostate and Breast Cancer Cell Apoptosis
- (2014) Peter Thomas et al. ENDOCRINOLOGY
- QSARINS-chem: Insubria datasets and new QSAR/QSPR models for environmental pollutants in QSARINS
- (2014) Paola Gramatica et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- GalaxySite: ligand-binding-site prediction by using molecular docking
- (2014) Lim Heo et al. NUCLEIC ACIDS RESEARCH
- OXER1, a G protein-coupled oxoeicosatetraenoid receptor, mediates the survival-promoting effects of arachidonate 5-lipoxygenase in prostate cancer cells
- (2013) Sivalokanathan Sarveswaran et al. CANCER LETTERS
- QSARINS: A new software for the development, analysis, and validation of QSAR MLR models
- (2013) Paola Gramatica et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- GalaxyRefine: protein structure refinement driven by side-chain repacking
- (2013) Lim Heo et al. NUCLEIC ACIDS RESEARCH
- QSAR Modeling is not “Push a Button and Find a Correlation”: A Case Study of Toxicity of (Benzo-)triazoles on Algae
- (2012) Paola Gramatica et al. Molecular Informatics
- Comparison of Different Approaches to Define the Applicability Domain of QSAR Models
- (2012) Faizan Sahigara et al. MOLECULES
- A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer
- (2012) Stefanie Blättermann et al. Nature Chemical Biology
- Novel Oligomeric Proanthocyanidin Derivatives Interact with Membrane Androgen Sites and Induce Regression of Hormone-Independent Prostate Cancer
- (2011) M. Kampa et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- On the Use of Local and Global QSPRs for the Prediction of Physico-chemical Properties of Polybrominated Diphenyl Ethers
- (2011) Ester Papa et al. Molecular Informatics
- GPRC6A regulates prostate cancer progression
- (2011) Min Pi et al. PROSTATE
- GPRC6A Mediates the Non-genomic Effects of Steroids
- (2010) Min Pi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 5-Oxo-ETE and the OXE receptor
- (2009) Gail E. Grant et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Conjugated and non-conjugated androgens differentially modulate specific early gene transcription in breast cancer in a cell-specific manner
- (2009) George Notas et al. STEROIDS
- Structural Requirements for Activation of the 5-Oxo-6E,8Z, 11Z,14Z-eicosatetraenoic Acid (5-Oxo-ETE) Receptor: Identification of a Mead Acid Metabolite with Potent Agonist Activity
- (2008) P. Patel et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Membrane androgen receptor activation triggers down-regulation of PI-3K/AKT/NF-kapaB activity and induces apoptotic responses via BAD, FasL and cacpase 3 in DU145 prostate cancer cells.
- (2008) Natalia Papadopoulou et al. Molecular Cancer
- GPRC6A Null Mice Exhibit Osteopenia, Feminization and Metabolic Syndrome
- (2008) Min Pi et al. PLoS One
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