Synthesis of methotrexate-betulonic acid hybrids and evaluation of their effect on artificial and Caco-2 cell membranes

Triphenylphosphonium Analogues of Betulin and Betulinic Acid with Biological Activity: A Comprehensive Review

(2019) Mirosława Grymel et al.   JOURNAL OF NATURAL PRODUCTS

Synthesis and biological evaluation of triterpenoid thiazoles derived from betulonic acid, dihydrobetulonic acid, and ursonic acid

(2019) Lucie Borková et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antimycobacterial activity of triterpenic A-ring azepanes

(2018) Natalya I. Medvedeva et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent progress in the antiviral activity and mechanism study of pentacyclic triterpenoids and their derivatives

(2018) Sulong Xiao et al.   MEDICINAL RESEARCH REVIEWS

Design, Synthesis, and SAR of C-3 Benzoic Acid, C-17 Triterpenoid Derivatives. Identification of the HIV-1 Maturation Inhibitor 4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-((2-(1,1-Dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)benzoic Acid (GSK3532795, BMS-955176)

(2018) Alicia Regueiro-Ren et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of novel benzylidene analogues of betulinic acid as potent cytotoxic agents

(2017) Nidhi Gupta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel Triazole Hybrids of Betulin: Synthesis and Biological Activity Profile

(2017) Ewa Bębenek et al.   MOLECULES

Hybrid molecules: The privileged scaffolds for various pharmaceuticals

(2016) Shaveta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A systematic review of pentacyclic triterpenes and their derivatives as chemotherapeutic agents against tropical parasitic diseases

(2016) MURTALA BINDAWA ISAH et al.   PARASITOLOGY

Design, synthesis of methotrexate-diosgenin conjugates and biological evaluation of their effect on methotrexate transport-resistant cells

(2016) Bangrong Cai et al.   STEROIDS

In vivo evaluation of isolated triterpenes and semi-synthetic derivatives as antimalarial agents

(2015) Luiz Francisco Rocha e Silva et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of heterocycle-modified betulinic acid derivatives as antitumor agents

(2015) Hai-Wei Cui et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Betulinic acid derived hydroxamates and betulin derived carbamates are interesting scaffolds for the synthesis of novel cytotoxic compounds

(2015) Jana Wiemann et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of betulonic acid derivatives as antitumor agents

(2015) Sheng-Jie Yang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of new betulinic acid–peptide conjugates and in vivo and in silico studies of the influence of peptide moieties on the triterpenoid core activity

(2015) Anastasiya I. Govdi et al.   MedChemComm

Functionalization, cyclization and antiviral activity of A-secotriterpenoids

(2014) Victoria V. Grishko et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Betulinic acid and its derivatives: a patent review (2008 – 2013)

(2014) René Csuk   EXPERT OPINION ON THERAPEUTIC PATENTS

Betulonic acid–peptide conjugates: synthesis and evaluation of anti-inflammatory activity

(2013) Anastasiya I. Govdi et al.   MENDELEEV COMMUNICATIONS

GPU Linear Algebra Libraries and GPGPU Programming for Accelerating MOPAC Semiempirical Quantum Chemistry Calculations

(2012) Julio Daniel Carvalho Maia et al.   Journal of Chemical Theory and Computation

Hybrid Molecules Incorporating Natural Products: Applications in Cancer Therapy, Neurodegenerative Disorders and Beyond

(2011) M. Decker   CURRENT MEDICINAL CHEMISTRY

Allobetulin and Its Derivatives: Synthesis and Biological Activity

(2011) Wim Dehaen et al.   MOLECULES

The effect of variations in phospholipid and sterol structure on the nature of lipid–sterol interactions in lipid bilayer model membranes

(2010) David A. Mannock et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Betulin-Derived Compounds as Inhibitors of Alphavirus Replication

(2009) Leena Pohjala et al.   JOURNAL OF NATURAL PRODUCTS

Cholesteric Liquid Crystals Doped with Molecules of Organic Scintillator Materials

(2009) L. N. Lisetski et al.   MOLECULAR CRYSTALS AND LIQUID CRYSTALS

Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents

(2009) Reen-Yen Kuo et al.   NATURAL PRODUCT REPORTS

Phase diagrams and lipid domains in multicomponent lipid bilayer mixtures

(2008) Gerald W. Feigenson   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES