Article
Cardiac & Cardiovascular Systems
Cheng Zhao, Xing Hao, Chao Xue, Yichen Zhao, Jie Han, Yixin Jia, Xiaotong Hou, Jiangang Wang
Summary: Acute right ventricular failure is a common and challenging condition in heart transplant recipients. While extracorporeal membrane oxygenation (ECMO) is an effective strategy for its treatment, the outcomes after weaning and during follow up need further investigation. This study aimed to evaluate the right-sided heart function in ECMO survivors following HTx.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Medicine, General & Internal
Dubravka Sipus, Kristina Krzelj, Zeljko Duric, Hrvoje Gasparovic, Davor Milicic, Jadranka Separovic Hanzevacki, Daniel Lovric
Summary: Heart transplant remains the gold standard therapy for end-stage heart failure, but using ECMO as a bridge to transplant may be a solution for critically ill patients. However, further research is needed to determine the superiority of direct bridging compared to bridging to durable MCS.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Samantha E. Halpern, Mary C. Wright, Gabrielle Madsen, Bryan Chow, Chelsea S. Harris, John C. Haney, Jacob A. Klapper, Brandi A. Bottiger, Matthew G. Hartwig
Summary: This study compared the impact of planned venoarterial extracorporeal membrane oxygenation (VA ECMO) and off-pump support on the textbook outcome in bilateral orthotopic lung transplantation (BOLT) patients without pulmonary hypertension. The results demonstrated that planned VA ECMO was associated with a higher likelihood of achieving textbook outcome compared to planned off-pump support.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2022)
Article
Engineering, Biomedical
Jae Kyeom Sim, Kyeongman Jeon, Gee Young Suh, Suryeun Chung, Yang Hyun Cho
Summary: VV ECMO is effective in supporting patients with respiratory failure, but issues like recirculation and right ventricular failure can arise. OxyRVAD, with its advantages of hemodynamic support and facilitating rehabilitation, can be a better option. Combining VV ECMO with OxyRVAD can overcome these challenges and lead to better outcomes for patients in need of lung transplantation.
Article
Cardiac & Cardiovascular Systems
Taylor Nordan, Andre C. Critsinelis, Shant H. Mahrokhian, Navin K. Kapur, Katherine L. Thayer, Frederick Y. Chen, Gregory S. Couper, Masashi Kawabori
Summary: The new donor heart allocation system has a positive impact on patients undergoing heart transplantation with extracorporeal membrane oxygenation, leading to shorter waitlist times, reduced preoperative comorbidities, and improved 180-day survival rates compared to the old system.
CIRCULATION-HEART FAILURE
(2021)
Article
Engineering, Biomedical
Georgia Brown, Katie M. Moynihan, Kristopher B. Deatrick, Aparna Hoskote, Hitesh S. Sandhu, Devon Aganga, Shriprasad R. Deshpande, Anuradha P. Menon, Thomas Rozen, Lakshmi Raman, Peta M. A. Alexander, Ravi Thiagarajan, Peter Roeleveld, Roberto Chiletti, Graeme MacLaren, Giles Peek
Summary: These guidelines are for neonates and children with cardiac failure requiring extracorporeal life support, covering patient selection, management, and weaning or bridging to other therapies. Important issues such as personnel, training, resources, follow-up, reporting, and quality assurance are addressed in other documents or specific to each center.
Article
Cardiac & Cardiovascular Systems
Jawad Salman, Beeke-Alina Bernhard, Fabio Ius, Reza Poyanmehr, Wiebke Sommer, Khalil Aburahma, Hani Alhadidi, Thierry Siemeni, Christian Kuehn, Murat Avsar, Axel Haverich, Gregor Warnecke, Igor Tudorache
Summary: This study aimed to identify risk factors for the need of intra-operative ECMO use in lung transplant patients with pulmonary fibrosis. Factors such as preoperative proof of pulmonary hypertension, mean pulmonary arterial pressure, and pulmonary vascular resistance were identified as risk factors, while increased recipient body surface area and higher cardiac output were protective factors. The post-operative course was found to be more complicated in the ECMO+ group, although long-term survival did not differ significantly among groups.
ANNALS OF THORACIC SURGERY
(2021)
Article
Surgery
Martin Balik, Jan Rulisek, Marek Flaksa, Michal Porizka, Frantisek Mosna, Jaroslav Lindner, Samuel Heller, Jan Belohlavek, Theodor Adla, Christof Schmid, Alois Philipp, Jan Havlin, Jan Burkert, Robert Lischke
Summary: Patients with pulmonary hypertension and end-stage lung disease may require the use of PA-LA shunt with an oxygenator to bridge their wait time for a lung transplant, but this technique carries the risk of multiple complications.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Cardiac & Cardiovascular Systems
Angelo Pisani, Wael Braham, Carlotta Brega, Moklhes Lajmi, Sophie Provenchere, Pichoy Danial, Soleiman Alkhoder, Marylou Para, Walid Ghodbane, Patrick Nataf
Summary: The study suggests that right axilary artery cannulation is a safe and reliable method for VA-ECMO support with a low rate of local complications.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2021)
Article
Medicine, General & Internal
Holger Thiele, Uwe Zeymer, Ibrahim Akin, Michael Behnes, Tienush Rassaf, Amir Abbas Mahabadi, Ralf Lehmann, Ingo Eitel, Tobias Graf, Tim Seidler, Andreas Schuster, Carsten Skurk, Daniel Duerschmied, Peter Clemmensen, Marcus Hennersdorf, Stephan Fichtlscherer, Ingo Voigt, Melchior Seyfarth, Stefan John, Sebastian Ewen, Axel Linke, Eike Tigges, Peter Nordbeck, Leonhard Bruch, Christian Jung, Jutta Franz, Philipp Lauten, Tomaz Goslar, Hans-Josef Feistritzer, Janine Poess, Eva Kirchhof, Taoufik Ouarrak, Steffen Schneider, Steffen Desch, Anne Freund, ECLS-SHOCK Investigators
Summary: In patients with acute myocardial infarction complicated by cardiogenic shock, early extracorporeal life support (ECLS) combined with standard medical treatment did not reduce mortality.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Medicine, General & Internal
Soo Jin Park, Do Jung Kim, You Sun Hong, Sang Hyun Lim, Jiye Park
Summary: Thyroid storm is a rare but life-threatening clinical feature that can be difficult to diagnose and requires thyroid function testing to rule out. For trauma patients, the possibility of thyroid storm should be considered when unexplained shock occurs, and appropriate treatment should be given promptly.
Article
Cardiac & Cardiovascular Systems
Ilhan Inci, Jonas Peter Ehrsam, Dirk Van Raemdonck, Laurens Joseph Ceulemans, Thorsten Krueger, Angela Koutsokera, Marco Schiavon, Eleonora Faccioli, Mario Nosotti, Lorenzo Rosso, Frank D'Ovidio, Miguel Leiva-Juarez, Clemens Aigner, Alexis Slama, Waleed Saleh, Khaled Manaa Alkattan, Pascal Alexandre Thomas, Geoffrey Brioude, Alberto Benazzo, Konrad Hoetzenecker
Summary: This study investigated the outcomes of recipients bridged to a first-time retransplantation (ReTx) by extracorporeal life support (ECLS). The results showed that the overall survival of the ECLS-ReTx group was significantly worse compared to the regular-ReTx and index-Tx groups. Risk factors such as recipient age, intertransplant interval, primary graft dysfunction as transplant indication, and type of ECLS were identified as significant factors affecting mortality in ECLS-ReTx recipients.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Critical Care Medicine
Jad Malas, Qiudong Chen, Tao Shen, Dominic Emerson, Tyler Gunn, Dominick Megna, Pedro Catarino, Michael Nurok, Michael Bowdish, Joanna Chikwe, Susan Cheng, Joseph Ebinger, Abirami Kumaresan
Summary: This study aimed to describe the institutional experience with extremely prolonged venovenous extracorporeal membrane oxygenation (ECMO) support for patients with acute respiratory failure. The study found that most patients in this cohort had adult respiratory distress syndrome (ARDS) secondary to COVID-19. Prolonged ECMO support was successful in weaning patients off and enabling their recovery, with a high rate of survival.
CRITICAL CARE MEDICINE
(2023)
Article
Medicine, General & Internal
Jun-yi Hou, Xin Li, Shou-guo Yang, Ji-li Zheng, Jie-fei Ma, Ying Su, Yi-jie Zhang, Ke-fang Guo, Guo-wei Tu, Zhe Luo
Summary: This study found that VA-ECMO provides effective treatment for severe PGD in patients after heart transplantation, promoting graft function recovery and reducing mortality rates.
FRONTIERS IN MEDICINE
(2021)
Article
Surgery
Julien Guihaire, Serena D'Avino, Francois Stephan, Martin Kloeckner, Ngoc Tram To, Agathe Potier, Maira Gaillard, Ramzi Ramadan, Jean-Luc Taupin, Jerome Le Pavec, Philippe Deleuze
Summary: This study retrospectively reviewed six patients who underwent plasmapheresis under extracorporeal membrane oxygenation (ECMO) before urgent heart transplantation. The results showed that plasmapheresis under ECMO support was associated with favorable early outcomes in highly sensitized candidates for urgent heart transplantation.
CLINICAL TRANSPLANTATION
(2021)
