Primate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor

TRIM5α Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection

(2022) Anastasia Selyutina et al.   Viruses-Basel

Inference of CRISPR Edits from Sanger Trace Data

(2022) David Conant et al.   CRISPR Journal

Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner

(2021) Zhou Zhong et al.   mBio

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core

(2020) Anastasia Selyutina et al.   Cell Reports

TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner

(2020) Molly Ohainle et al.   PLoS Pathogens

Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races

(2020) Jeannette L Tenthorey et al.   eLife

Restriction of HIV-1 and other retroviruses by TRIM5

(2019) Barbie K. Ganser-Pornillos et al.   NATURE REVIEWS MICROBIOLOGY

Cyclophilin A protects HIV-1 from restriction by human TRIM5α

(2019) Kyusik Kim et al.   Nature Microbiology

Trivalent RING Assembly on Retroviral Capsids Activates TRIM5 Ubiquitination and Innate Immune Signaling

(2018) Adam J. Fletcher et al.   Cell Host & Microbe

Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines

(2018) Sean Matthew McCauley et al.   Nature Communications

RNA-Associated Early-Stage Antiviral Factor Is a Major Component of Lv2 Restriction

(2017) Kelly M. Marno et al.   JOURNAL OF VIROLOGY

TRIM5α-Mediated Ubiquitin Chain Conjugation Is Required for Inhibition of HIV-1 Reverse Transcription and Capsid Destabilization

(2015) Edward M. Campbell et al.   JOURNAL OF VIROLOGY

TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling

(2015) Josefina Lascano et al.   JOURNAL OF VIROLOGY

Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration

(2015) Massimo Pizzato et al.   PLoS Pathogens

Host and Viral Determinants of Mx2 Antiretroviral Activity

(2014) Idoia Busnadiego et al.   JOURNAL OF VIROLOGY

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

Novel restriction factor RNA-associated early-stage anti-viral factor (REAF) inhibits human and simian immunodeficiency viruses

(2014) Kelly M Marno et al.   Retrovirology

Binding of the rhesus TRIM5α PRYSPRY domain to capsid is necessary but not sufficient for HIV-1 restriction

(2013) Yang Yang et al.   VIROLOGY

Rules of Engagement: Molecular Insights from Host-Virus Arms Races

(2012) Matthew D. Daugherty et al.   Annual Review of Genetics

Human Immunodeficiency Virus Type 1 Capsid Mutation N74D Alters Cyclophilin A Dependence and Impairs Macrophage Infection

(2012) Zandrea Ambrose et al.   JOURNAL OF VIROLOGY

Determinants of the Higher Order Association of the Restriction Factor TRIM5α and Other Tripartite Motif (TRIM) Proteins

(2011) Xing Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

(2011) Thomas Pertel et al.   NATURE

Visualization of a proteasome-independent intermediate during restriction of HIV-1 by rhesus TRIM5α

(2008) Edward M. Campbell et al.   JOURNAL OF CELL BIOLOGY

The TRIM5  B-Box 2 Domain Promotes Cooperative Binding to the Retroviral Capsid by Mediating Higher-Order Self-Association

(2008) X. Li et al.   JOURNAL OF VIROLOGY

Cyclophilin A-Dependent Restriction of Human Immunodeficiency Virus Type 1 Capsid Mutants for Infection of Nondividing Cells

(2008) M. Qi et al.   JOURNAL OF VIROLOGY

Primate Lentivirus Capsid Sensitivity to TRIM5 Proteins

(2008) Z. Kratovac et al.   JOURNAL OF VIROLOGY

Biochemical and Biophysical Characterization of a Chimeric TRIM21-TRIM5  Protein

(2008) A. K. Kar et al.   JOURNAL OF VIROLOGY