The KT Jeang retrovirology prize 2023: Thumbi Ndung’u

Antigen Presenting Cells Contribute to Persistent Immune Activation Despite Antiretroviral Therapy Initiation During Hyperacute HIV-1 Infection

(2021) Kewreshini K. Naidoo et al.   Frontiers in Immunology

Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection

(2020) Daniel M. Muema et al.   BMC Medicine

Differential Vpu-mediated CD4 and tetherin downregulation function among major HIV-1 group M subtypes

(2020) Gisele Umviligihozo et al.   JOURNAL OF VIROLOGY

Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5

(2020) Steven W. Jin et al.   PLoS Pathogens

Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection

(2019) Zaza M. Ndhlovu et al.   Science Translational Medicine

HIV-1 DNA sequence diversity and evolution during acute subtype C infection

(2019) Guinevere Q. Lee et al.   Nature Communications

Why and where an HIV cure is needed and how it might be achieved

(2019) Thumbi Ndung’u et al.   NATURE

Detection and treatment of Fiebig stage I HIV-1 infection in young at-risk women in South Africa: a prospective cohort study

(2018) Krista L Dong et al.   Lancet HIV

Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity Are Consistent with Intersubtype Differences in HIV-1 Disease Progression

(2017) Marion W. Kiguoya et al.   JOURNAL OF VIROLOGY

Mother-to-Child HIV Transmission Bottleneck Selects for Consensus Virus with Lower Gag-Protease-Driven Replication Capacity

(2017) Vanessa L. Naidoo et al.   JOURNAL OF VIROLOGY

Functional characterization of Vif proteins from HIV-1 infected patients with different APOBEC3G haplotypes

(2016) Kavidha Reddy et al.   AIDS

Association of polymorphisms in the regulatory region of the cyclophilin A gene (PPIA) with gene expression and HIV/AIDS disease progression

(2016) Paradise Madlala et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

CD8+T Cell Breadth andEx VivoVirus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles

(2016) Catherine K. Koofhethile et al.   JOURNAL OF VIROLOGY

Broad and persistent Gag-specific CD8+ T-cell responses are associated with viral control but rarely drive viral escape during primary HIV-1 infection

(2015) Mopo Radebe et al.   AIDS

Magnitude and Kinetics of CD8 + T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point

(2015) Zaza M. Ndhlovu et al.   IMMUNITY

High Frequency of Transmitted HIV-1 Gag HLA Class I-Driven Immune Escape Variants but Minimal Immune Selection over the First Year of Clade C Infection

(2015) Kamini Gounder et al.   PLoS One

TRIM5  and TRIM22 Are Differentially Regulated According to HIV-1 Infection Phase and Compartment

(2014) R. Singh et al.   JOURNAL OF VIROLOGY

The Fitness Landscape of HIV-1 Gag: Advanced Modeling Approaches and Validation of Model Predictions by In Vitro Testing

(2014) Jaclyn K. Mann et al.   PLoS Computational Biology

Translating HIV Sequences into Quantitative Fitness Landscapes Predicts Viral Vulnerabilities for Rational Immunogen Design

(2013) Andrew L. Ferguson et al.   IMMUNITY

Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes

(2013) Jaclyn K Mann et al.   Retrovirology

Impact of HLA-B*81-Associated Mutations in HIV-1 Gag on Viral Replication Capacity

(2012) J. K. Wright et al.   JOURNAL OF VIROLOGY

Limited Immunogenicity of HIV CD8+ T-Cell Epitopes in Acute Clade C Virus Infection

(2011) Mopo Radebe et al.   JOURNAL OF INFECTIOUS DISEASES

Influence of Gag-Protease-Mediated Replication Capacity on Disease Progression in Individuals Recently Infected with HIV-1 Subtype C

(2011) J. K. Wright et al.   JOURNAL OF VIROLOGY

Gag-Protease-Mediated Replication Capacity in HIV-1 Subtype C Chronic Infection: Associations with HLA Type and Clinical Parameters

(2010) Jaclyn K. Wright et al.   JOURNAL OF VIROLOGY

APOBEC3G expression is dysregulated in primary HIV-1 infection and polymorphic variants influence CD4+ T-cell counts and plasma viral load

(2009) Kavidha Reddy et al.   AIDS

Interleukin‐10 Promoter Polymorphisms Influence HIV‐1 Susceptibility and Primary HIV‐1 Pathogenesis

(2009) Dshanta D. Naicker et al.   JOURNAL OF INFECTIOUS DISEASES

Human TRIM5α Expression Levels and Reduced Susceptibility to HIV‐1 Infection

(2009) Shamman Sewram et al.   JOURNAL OF INFECTIOUS DISEASES