Transmitted/founder SHIV.D replicates in the brain, causes neuropathogenesis, and persists on combination antiretroviral therapy in rhesus macaques

Antiretroviral therapy restores the homeostatic state of microglia in SIV‐infected rhesus macaques

(2022) Andrew J. Trease et al.   JOURNAL OF LEUKOCYTE BIOLOGY

New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention and Cure

(2021) Hui Li et al.   JOURNAL OF VIROLOGY

Advances in SIV/SHIV Non-Human Primate Models of NeuroAIDS

(2021) Sonia Moretti et al.   Pathogens

HIV-1 persistence in the CNS: Mechanisms of latency, pathogenesis and an update on eradication strategies

(2021) Shilpa Sonti et al.   VIRUS RESEARCH

Novel transmitted/founder SHIVs for HIV latency and cure research

(2020) Anya M. Bauer et al.   JOURNAL OF VIROLOGY

Simian Immunodeficiency Virus-Infected Memory CD4+ T Cells Infiltrate to the Site of Infected Macrophages in the Neuroparenchyma of a Chronic Macaque Model of Neurological Complications of AIDS

(2020) Cheri A. Lee et al.   mBio

The Brain Retains: Nonhuman Primate Models for Pediatric HIV-1 in the CNS

(2020) Veronica Obregon-Perko et al.   Current HIV/AIDS Reports

Important role of microglia in HIV-1 associated neurocognitive disorders and the molecular pathways implicated in its pathogenesis

(2020) A Borrajo et al.   ANNALS OF MEDICINE

Advances in simian--human immunodeficiency viruses for nonhuman primate studies of HIV prevention and cure

(2020) Anya M. Bauer et al.   Current Opinion in HIV and AIDS

Editor’s Commentary for Special Issue: “The Role of Macrophages in HIV Persistence”

(2019) Tricia H. Burdo   Journal of Neuroimmune Pharmacology

SHIV.CH505 infection of rhesus macaques results in persistent viral replication and induces intestinal immunopathology

(2019) Katharine J. Bar et al.   JOURNAL OF VIROLOGY

HIV-1 persistence in the central nervous system: viral and host determinants during antiretroviral therapy

(2019) EF Balcom et al.   Current Opinion in Virology

Microglial Cells: The Main HIV-1 Reservoir in the Brain

(2019) Clementine Wallet et al.   Frontiers in Cellular and Infection Microbiology

Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques

(2018) Denise C. Hsu et al.   JOURNAL OF VIROLOGY

Next-generation in situ hybridization approaches to define and quantify HIV and SIV reservoirs in tissue microenvironments

(2018) Claire Deleage et al.   Retrovirology

Barriers for HIV Cure: The Latent Reservoir

(2018) Sergio Castro-Gonzalez et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Macrophages but not Astrocytes Harbor HIV DNA in the Brains of HIV-1-Infected Aviremic Individuals on Suppressive Antiretroviral Therapy

(2018) Allen Ko et al.   Journal of Neuroimmune Pharmacology

HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency

(2017) George N. Llewellyn et al.   JOURNAL OF NEUROVIROLOGY

Mechanisms of CNS Viral Seeding by HIV + CD14 + CD16 + Monocytes: Establishment and Reseeding of Viral Reservoirs Contributing to HIV-Associated Neurocognitive Disorders

(2017) Mike Veenstra et al.   mBio

Envelope residue 375 substitutions in simian–human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques

(2016) Hui Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 latency and virus production from unintegrated genomes following direct infection of resting CD4 T cells

(2016) Chi N. Chan et al.   Retrovirology

HIV-1 Reservoirs During Suppressive Therapy

(2016) Kirston Barton et al.   TRENDS IN MICROBIOLOGY

Bottlenecks in HIV-1 transmission: insights from the study of founder viruses

(2015) Sarah B. Joseph et al.   NATURE REVIEWS MICROBIOLOGY

HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days—Implications for HIV Remission

(2015) Mykola Pinkevych et al.   PLoS Pathogens

Compartmentalization, Viral Evolution, and Viral Latency of HIV in the CNS

(2015) Maria M. Bednar et al.   Current HIV/AIDS Reports

Emergence of CD4 Independence Envelopes and Astrocyte Infection in R5 Simian-Human Immunodeficiency Virus Model of Encephalitis

(2014) K. Zhuang et al.   JOURNAL OF VIROLOGY

HIV-1 Latency in Monocytes/Macrophages

(2014) Amit Kumar et al.   Viruses-Basel

Monocyte/macrophages and their role in HIV neuropathogenesis

(2013) Tricia H. Burdo et al.   IMMUNOLOGICAL REVIEWS

Effect of HIV clade differences on the onset and severity of HIV-associated neurocognitive disorders

(2013) William Tyor et al.   JOURNAL OF NEUROVIROLOGY

Lineage-Specific Differences between Human and Simian Immunodeficiency Virus Regulation of gp120 Trimer Association and CD4 Binding

(2012) A. Finzi et al.   JOURNAL OF VIROLOGY

Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectious molecular clones

(2012) Joshua Baalwa et al.   VIROLOGY

The definition of HIV-associated neurocognitive disorders: are we overestimating the real prevalence?

(2011) Magnus Gisslén et al.   BMC INFECTIOUS DISEASES

HIV Subtype D Is Associated with Dementia, Compared with Subtype A, in Immunosuppressed Individuals at Risk of Cognitive Impairment in Kampala, Uganda

(2009) Ned Sacktor et al.   CLINICAL INFECTIOUS DISEASES

HIV interactions with monocytes and dendritic cells: viral latency and reservoirs

(2009) Christopher M Coleman et al.   Retrovirology

Compartmentalized Human Immunodeficiency Virus Type 1 Originates from Long-Lived Cells in Some Subjects with HIV-1–Associated Dementia

(2009) Gretja Schnell et al.   PLoS Pathogens

SHIV-1157i and passaged progeny viruses encoding R5 HIV-1 clade C env cause AIDS in rhesus monkeys

(2008) Michael Humbert et al.   Retrovirology

Changes in the incidence and predictors of human immunodeficiency virus-associated dementia in the era of highly active antiretroviral therapy

(2007) Krishnan Bhaskaran et al.   ANNALS OF NEUROLOGY