Advances in the expression and purification of human PARP1: A user-friendly protocol

The role of PARP1 in neurodegenerative diseases and aging

(2021) Kanmin Mao et al.   FEBS Journal

PARP Power: A Structural Perspective on PARP1, PARP2, and PARP3 in DNA Damage Repair and Nucleosome Remodelling

(2021) Lotte van Beek et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PARP-1-Associated Pathological Processes: Inhibition by Natural Polyphenols

(2021) Natalya V. Maluchenko et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer

(2021) Johannes Rudolph et al.   MOLECULAR CELL

HPF1 dynamically controls the PARP1/2 balance between initiating and elongating ADP-ribose modifications

(2021) Marie-France Langelier et al.   Nature Communications

Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins

(2019) Elizaveta E Alemasova et al.   NUCLEIC ACIDS RESEARCH

The Role of PARPs in Inflammation—and Metabolic—Related Diseases: Molecular Mechanisms and Beyond

(2019) Ke et al.   Cells

A method to probe protein structure from UV absorbance spectra

(2019) Amadeo B. Biter et al.   ANALYTICAL BIOCHEMISTRY

Selective targeting of PARP-1 zinc finger recognition domains with Au(iii) organometallics

(2018) Margot N. Wenzel et al.   CHEMICAL COMMUNICATIONS

Metal binding properties of zinc fingers with a naturally altered metal binding site

(2018) Katarzyna Kluska et al.   Metallomics

Acetylation blocks DNA damage–induced chromatin ADP-ribosylation

(2018) Glen Liszczak et al.   Nature Chemical Biology

Novel PARP-1 Inhibitor Scaffolds Disclosed by a Dynamic Structure-Based Pharmacophore Approach

(2017) Salete J. Baptista et al.   PLoS One

Unusual Zn(II) Affinities of Zinc Fingers of Poly(ADP-ribose) Polymerase 1 (PARP-1) Nuclear Protein

(2015) Karolina Bossak et al.   CHEMICAL RESEARCH IN TOXICOLOGY

PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain

(2015) Jennine M. Dawicki-McKenna et al.   MOLECULAR CELL

PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage

(2015) Amanda A. Riccio et al.   NUCLEIC ACIDS RESEARCH

PARP-2 and PARP-3 are selectively activated by 5′ phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1

(2014) Marie-France Langelier et al.   NUCLEIC ACIDS RESEARCH

Targeting PARP-1 Allosteric Regulation Offers Therapeutic Potential against Cancer

(2013) J. D. Steffen et al.   CANCER RESEARCH

A systematic analysis of the PARP protein family identifies new functions critical for cell physiology

(2013) Sejal Vyas et al.   Nature Communications

An Escherichia coli strain for expression of the connexin45 carboxyl terminus attached to the 4th transmembrane domain

(2013) Jennifer L. Kopanic et al.   Frontiers in Pharmacology

PARPs and the DNA damage response

(2012) F. G. Sousa et al.   CARCINOGENESIS

Alternative Modes of Binding of Poly(ADP-ribose) Polymerase 1 to Free DNA and Nucleosomes

(2012) Nicholas J. Clark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for DNA Damage-Dependent Poly(ADP-ribosyl)ation by Human PARP-1

(2012) M.-F. Langelier et al.   SCIENCE

Structural studies of the PARP-1 BRCT domain

(2011) Paul A Loeffler et al.   BMC STRUCTURAL BIOLOGY

A spectrophotometric method for the determination of zinc, copper, and cobalt ions in metalloproteins using Zincon

(2009) Crystal E. Säbel et al.   ANALYTICAL BIOCHEMISTRY

The maltodextrin transport system and metabolism in Lactobacillus acidophilus NCFM and production of novel α-glucosides through reverse phosphorolysis by maltose phosphorylase

(2009) Hiroyuki Nakai et al.   FEBS Journal

Removal of detergents from protein digests for mass spectrometry analysis

(2008) Yee-Guide Yeung et al.   ANALYTICAL BIOCHEMISTRY