Article
Biochemistry & Molecular Biology
Miey Park, Varun Jaiswal, Kihyun Kim, Julan Chun, Mi-Jin Lee, Jae-Ho Shin, Hae-Jeung Lee
Summary: This research investigates the effects of mulberry leaf supplements on overweight dogs and demonstrates that mulberry leaf can reduce blood glucose levels and body weight, thus providing anti-obesity and anti-inflammatory effects.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biotechnology & Applied Microbiology
Xin Cui, Yan Li, Tingting Han, Suzhen Yang, Yan Liang, Zhe Wang, Ting Wang, Zhenshang Xu
Summary: In this study, the properties of Bacillus siamensis-fermented kelp as a raw material for cosmetics were explored. It was found that the fermented kelp had high content of polysaccharide, fucose, and alginic acid, as well as good antioxidant capacity. The fermentation broth also showed anti-wrinkle and skin-repairing effects on skin cells. Therefore, it can be considered as a potential cosmetic raw material.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2022)
Article
Biotechnology & Applied Microbiology
Ningwei Wang, Yi Xiong, Xuekai Wang, Linna Guo, Yanli Lin, Kuikui Ni, Fuyu Yang
Summary: This study found that the addition of lactic acid bacteria could significantly improve the fermentation quality of paper mulberry silage and reduce the amount of anti-nutrient factors.
FERMENTATION-BASEL
(2022)
Article
Nutrition & Dietetics
A. Lum Han, Su-Ji Jeong, Myeong-Seon Ryu, Hee-Jong Yang, Do-Youn Jeong, Do-Sim Park, Hee Kyung Lee
Summary: The study found that Kochujang, a traditional Korean chili paste, has anti-obesity effects in cell and animal models. In experiments with overweight and obese adults, consumption of Kochujang resulted in reduced waist circumference, decreased cholesterol levels, and decreased visceral fat. The presence of beneficial microbes in Kochujang also played a role in improving lipid profiles.
Article
Food Science & Technology
Sentai Liao, Xiaoshan Long, Yuxiao Zou, Fan Liu, Qian Li
Summary: This study investigated the effects of mulberry leaf powder and components on preventing obesity and regulating lipid metabolism. The results showed that the fiber and phenolics of mulberry leaf have the potential for development of weight-loss functional foods.
JOURNAL OF FOOD SCIENCE
(2021)
Article
Pharmacology & Pharmacy
Na Rae Shin, Shambhunath Bose, Yura Choi, Young-Mi Kim, Young-Won Chin, Eun-Ji Song, Young-Do Nam, Hojun Kim
Summary: The study revealed that fermented Panax notoginseng extract showed benefits in reducing food and calorie intake, as well as affecting gut microbial composition leading to anti-obesity effects.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Food Science & Technology
Lingyue Shan, Akanksha Tyagi, Xiuqin Chen, Pianpian Yan, Deog Hwan Oh
Summary: Nowadays, obesity is a major global public health issue. Medical and surgical treatments for obesity often have adverse side effects. In this study, the anti-obesity effect of five different types of seeds cultivated in South Korea was evaluated. Adzuki beans had the highest inhibitory activity against lipase and alpha-amylase, and fermentation of adzuki beans with Pediococcus acidilactici further enhanced their anti-obesity properties. Metabolomics analysis revealed several metabolites and metabolic pathways that contributed to the improved anti-obesity ability of fermented adzuki beans. These findings suggest that fermenting adzuki beans with P. acidilactici could be a promising method for developing functional foods with anti-obesity properties.
Article
Food Science & Technology
Min Woo Kim, Yu-Jin Ham, Hyun-Bok Kim, Ji young Lee, Jung-Dae Lim, Hyun-Tai Lee
Summary: The present study investigated the anti-obesity effects of mature silkworm powder in adult mice. The results showed that mature silkworm powder significantly suppressed body weight gain, intra-abdominal adipose tissue, and food efficiency in both normal diet-fed and high-fat diet-fed mice. It also decreased food intake and liver weight in high-fat diet-fed mice, indicating appetite suppression and reduced conversion of feed into body weight. Furthermore, mature silkworm powder lowered the levels of glucose, triglyceride, cholesterol, liver enzymes, and alkaline phosphatase in the serum. These findings suggest that mature silkworm powder has potent anti-obesity effects and is safe for long-term use as a potential therapeutic and/or nutraceutical.
Article
Plant Sciences
Jie Mei, Rong Yang, Qiaohong Yang, Wencheng Wan, Xiaoyong Wei
Summary: The study found that chrysin can reduce the amount of triglycerides by directly downregulating the inflammation-related target proteins ANXA2 and HSP-60, exerting an anti-obesity role.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Daphne K. Weikart, Vijaya V. Indukuri, Kathryn C. Racine, Kiana M. Coleman, Jasna Kovac, Darrell W. Cockburn, Helene Hopfer, Andrew P. Neilson, Joshua D. Lambert
Summary: Fermentation and roasting protocols do not affect the anti-obesity and anti-inflammatory efficacy of cocoa in obese mice. Cocoa supplementation reduces body weight gain, increases colonic length, and decreases gut permeability in both male and female mice. There are significant sex differences in the effects of both high-fat diet and cocoa supplementation.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2022)
Article
Nutrition & Dietetics
Mi Hwa Park, Yu Jeong Yeom, Dariimaa Ganbat, Min Kyeong Kim, Seong-Bo Kim, Yong-Jik Lee, Sang-Jae Lee
Summary: Microbial fermentation of Abelmoschus manihot using Bacillaceae strains showed antioxidant and anti-inflammatory effects, especially Bacillus licheniformis CP6 fermented A. manihot extract (FAME) inhibited nitric oxide production and reduced inflammatory mediators in LPS-stimulated macrophages, suggesting its potential use for inflammation-related disorders.
Article
Biochemistry & Molecular Biology
Zexin Gao, Chuanchao Wu, Jianrong Wu, Li Zhu, Minjie Gao, Zichao Wang, Zhitao Li, Xiaobei Zhan
Summary: This study extracted the exopolysaccharide BPS-2 from Bacillus thuringiensis and found that it has strong anti-digestive capacity, as well as anti-inflammatory and antioxidant effects in vitro. These findings provide a basis for biopharmaceutical applications of BPS-2.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Food Science & Technology
Anna Paula Azevedo de Carvalho, Carlos Adam Conte-Junior
Summary: Brazil's diverse native flora contains bioactive compounds that show high inhibition rates against various parasites, viruses, fungi, and bacteria, often outperforming reference antibiotics. These compounds demonstrate cancer cell selectivity, no cytotoxicity to healthy cells, and a balance between prooxidants and antioxidants that can control cancer cell proliferation. Additionally, the flora can help avoid oxidative stress and other risk factors associated with metabolic disorders.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Ji-Young Park, Myung Wook Song, Kee-Tae Kim, Hyun-Dong Paik
Summary: The study found that fermented hydroponic ginseng, cultured with Bacillus strains, exhibited stronger antioxidative, anti-inflammatory, and antimelanogenic effects compared to traditionally cultured ginseng. This suggests that fermented hydroponic ginseng has the potential to be used in cosmetic and pharmaceutical applications.
Article
Biochemistry & Molecular Biology
Xueqian Zhang, Ying You, LiLong Wang, Chunqing Ai, Linjuan Huang, Songtao Wang, Zhongfu Wang, Shuang Song, Beiwei Zhu
Summary: Previous studies have shown that fucoidan can resist high-fat-diet-induced obesity by modulating the composition of gut microbiota. In this study, the anti-obesity effects of fucoidan were compared between mice with different gut microbiota communities. The results demonstrated that mice with different initial gut microbiota responded differently to fucoidan supplementation, and certain gut bacteria were required for the anti-obesity effects.
Article
Clinical Neurology
Shuting Chen, Jiale Wang, Juping Wang, Qian Gao, Xiaotian Zhao, Hongwei Guan, Tong Wang
Summary: The association between sleep-disordered breathing and impaired fasting glucose and type 2 diabetes can be explained by the mediating effect of obesity, especially central obesity.
SLEEP AND BREATHING
(2023)
Article
Public, Environmental & Occupational Health
Gifty Marley, Rayner Kay Jin Tan, Dan Wu, Tong Wang, Murong Sun, Qilei Sheng, Margaret Elizabeth Holly, Takhona Grace Hlatshwako, Cheng Wang, Weiming Tang, Rohit Ramaswamy, Ligang Yang, Danyang Luo, Sean S. Sylvia, Kurt Gray, David Van Duin, Heping Zheng, Joseph D. Tucker
Summary: This study proposes a randomized controlled trial (PIONEER) to evaluate the effectiveness of two pay-it-forward strategies in promoting gonorrhea and chlamydia testing uptake among MSM and male STD patients in China. It aims to increase testing rates and provide a new financial mechanism to sustain STD screening among sexual minorities in low- and middle-income countries.
Article
Thermodynamics
Qiyan Wu, Xiangbao Meng, Yansong Zhang, Yang Wu, Wenjiao Dai, Li Liu, Lei Shi, Tong Wang
Summary: This paper conducted flame propagation and explosion pressure suppression experiments of lycopodium powder explosion using Hartmann experimental system and 20 L spherical explosion experimental system, respectively. The inhibition mechanism of montmorillonite powder and hydroxy- montmorillonite powder on the explosion of lycopodium powder was analyzed based on the FTIR curves before and after the explosion as well as the reaction involving it and inhibitors. The experimental results showed that montmorillonite powder and hydroxy-montmorillonite powder had a certain inhibition effect on lycopodium powder explosion, with the latter showing better results.
COMBUSTION SCIENCE AND TECHNOLOGY
(2023)
Article
Engineering, Electrical & Electronic
Tong Wang, Fubin Wu, Haoran Lu, Shengzhou Xu
Summary: Lung cancer is a serious threat to human life and detecting lung nodules at an early stage can improve patient survival. In this study, a CA-UNet model based on convolution and attention fusion was proposed to accurately segment lung nodule regions in CT images. The model incorporates global feature extraction and channel attention to improve segmentation performance. Experimental results on a lung nodule database demonstrated superior performance compared to other methods.
INTERNATIONAL JOURNAL OF IMAGING SYSTEMS AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Zongyi Zhang, Yanan Zhao, Jing Cai, Tong Wang, Yujie Song, Jingyi Lu, Hairuo Du, Wenfang Wang, Yan Zhao, Lei Guo
Summary: This study aimed to optimize the liquid-solid extraction of Wu Wei Zi extracts (WWZE) against Vibrio parahaemolyticus, identify its main components, and investigate the anti-biofilm action. The results showed that schisantherin A and schizandrol B were the main antibacterial components of WWZE. WWZE could effectively inhibit the formation and clear mature biofilm of V. parahaemolyticus by destroying cell membrane integrity, inhibiting intercellular polysaccharide adhesin (PIA) synthesis, reducing extracellular DNA secretion, and decreasing the metabolic activity of the biofilm. This study provides a basis for the application of WWZE in the preservation of aquatic products.
Article
Environmental Sciences
Ben Li, Xiaohan Chang, Xiaomin Liang, Ting Liu, Yongmei Shen, Qianwen Zhang, Xiaohui Yang, Yi Lyu, Liangpo Liu, Jianquan Guo, Meiqiong Wu, Yi Gao, Xiaoyan Yan, Tong Wang, WenPing Zhang, Yulan Qiu, JinPing Zheng
Summary: Epidemiological studies have demonstrated that ambient fine particulate matter (PM) can lead to various neurodegenerative diseases, including Alzheimer's disease. This study reveals that PM with an aerodynamic diameter of <= 0.2 μm can induce the formation of A1 reactive astrocytes (A1s) through the activation of neuroinflammatory microglia. The A1s promote synaptic damage in neurons by secreting complement 3 (C3).
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Public, Environmental & Occupational Health
Zhiyao Li, Boran Yang, Jiale Wang, Yanchao Wen, Jianguo Xu, Li Ling, Tong Wang
Summary: This study explored the global diversity in border policies and found that high-income countries had the most durable bans on regions, while low-income countries applied more lenient measures such as screening and quarantine. In terms of the effectiveness of these policies, longer maintenance of border quarantine was associated with lower COVID-19 incidence in high-prevalent countries, but longer duration of imposing bans on regions showed no suppressing effects and even led to higher COVID-19 incidence in medium and high transmission severity countries.
TRAVEL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Plant Sciences
Honghong Deng, Yao Li, Changqing Pang, Kun Zhang, Xinbo Tian, Tong Wang, Yan Liang, Zunzhen He, Yuxuan Lang, Jinbao Fang, Lijin Lin, Jin Wang, Xiulan Lv, Hui Xia, Dong Liang
Summary: China, as the largest kiwifruit producer in the world, faces the challenge of low yield per unit area compared to global average and other countries. This study developed an improved overhead pergolas trellis system, the umbrella-shaped trellis system, for Donghong kiwifruit. The yield on the new system was more than two times higher than the traditional system, with maintained external fruit quality and improved internal fruit quality. The increased vegetative growth of canes and shading conditions contributed to these yield improvements.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Environmental Sciences
Mengyao Xia, Xiaowei Chuai, Liang Zhai, Ai Xiang, Tong Wang
Summary: High-resolution carbon neutrality mapping is crucial for guiding carbon sequestration increase and carbon emissions reduction. This study utilized multiple sources of big data, including high-precision satellite data and field data, to simulate the spatial distribution of carbon neutrality and compare the influencing factors of industry structure, land use, and landscape between Beijing and Shanghai. The results show that carbon emissions in Shanghai are 1.8 times higher than Beijing, and Shanghai has limited natural green land and little carbon sink. The study also reveals the distribution of carbon emissions and sinks in different regions and highlights the importance of industry and land use structure in carbon neutrality.
Article
Acoustics
Tong Wang, Xinliang Fan, Fengshou Sun
Summary: In this paper, a new iterative method is proposed for accurately identifying mechanical connections, especially suitable for joints with many interface degrees of freedom in the presence of limited frequency response function data and large experimental noise. The proposed method updates the joint properties iteratively by minimizing the differences between predicted responses and measured ones using basic identification equations and a linear equation system. The validity and applicability of the method are verified through numerical simulations and identification of a real end-toothed connection.
JOURNAL OF SOUND AND VIBRATION
(2023)
Article
Environmental Sciences
Hongmei Zhang, Jingjing Cao, Aixiang Liu, Qian Gao, Jisheng Nie, Xiaoling Zhou, Jianjun Huang, Chenming Sun, Tong Wang
Summary: This study examined the association between urinary OH-PAHs concentration and occupational stress in coal miners. 671 underground coal miners were sampled from Datong, China, and their occupational stress was assessed using the OSI-R. The results showed that LMW OH-PAHs were positively associated with ORQ and PSQ scores, but not with PRQ scores.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Thermodynamics
Yu-Xiu Zhong, Xin Wang, Gang Xu, Xinyu Ning, Lin Zhou, Wen Tang, Ming-Hao Wang, Tong Wang, Jun Xu, Long Jiang, Yi Wang, Sheng Su, Song Hu, Jun Xiang
Summary: Boiler slagging and high-temperature corrosion are major issues faced by coal-fired boilers due to the use of low-NOx burners. This study used sample characterization, numerical simulation, and field adjustments to investigate the impact of coal quality and boiler air distribution on these problems. Characterization results confirmed that alkali metals compounds were responsible for slagging and the boiler was experiencing sulfide type corrosion. Adjustments to the air distribution were proposed and experiments conducted, showing positive results in mitigating the reducing atmosphere and reducing peak temperatures, providing guidance for preventing slagging and high-temperature corrosion in boilers.
Article
Mathematical & Computational Biology
Hongwei Sun, Qian Gao, Guiming Zhu, Chunlei Han, Haosen Yan, Tong Wang
Summary: Penalized Cox regression can determine biomarkers in high-dimensional genomic data related to disease prognosis. A robust penalized Cox model (Rwt MTPL-EN) and a new algorithm (AR-Cstep) are proposed to improve prediction accuracy and detect influential observations. Rwt MTPL-EN outperforms Elastic Net (EN) in the presence of outliers and has higher accuracy in detecting outliers.
MATHEMATICAL BIOSCIENCES AND ENGINEERING
(2023)
Article
Integrative & Complementary Medicine
Ai-Ping Chen, Zi-Juan Zhang, Jing-Zhong Li, Ling Zuo, Ya-Xing Cheng, Dong Deng, Xue-Li Li, Xiao-Yun Ma, Da Man, Ming-Huang Zheng, Jian Chen, Bo Wen, Juan Wang, Jian-Guo Zhou, Hui-Hui Zhao
Summary: The study revealed that Wuweijiangyasan (WWJYS) has significant depressurization, analgesic, sedative, and lipid-lowering effects, and its depressurization mechanism may function through multiple signal pathways, particularly in improving blood vessel function and intervening inflammation.
WORLD JOURNAL OF TRADITIONAL CHINESE MEDICINE
(2023)
Article
Integrative & Complementary Medicine
Zi-Juan Zhang, Xin Li, Ya-Xing Cheng, Amatti Jorigori, Dongzhu Renqing, Li-Ping Pan, Meng Mao, Xiao-Qiao Ren, Hui-Hui Zhao
Summary: The theories related to mind-body medicine in Tibetan medicine have been confirmed by modern research. Treatment for psychosomatic diseases should be conducted simultaneously for both the mind and body, and emphasis should be placed on cultivating psychological and physical defense mechanisms before the onset of diseases.
WORLD JOURNAL OF TRADITIONAL CHINESE MEDICINE
(2023)
