Synthesis and evaluation of l-dopa and L-Tyr derivatives as amyloid-beta aggregation inhibitors

New Approved Drugs Appearing in the Pharmaceutical Market in 2022 Featuring Fragments of Tailor-Made Amino Acids and Fluorine

(2023) Nana Wang et al.   MOLECULES

The Latest FDA-Approved Pharmaceuticals Containing Fragments of Tailor-Made Amino Acids and Fluorine

(2022) Qian Wang et al.   Pharmaceuticals

The total synthesis of berberine and selected analogues, and their evaluation as amyloid beta aggregation inhibitors

(2021) Misato Tajiri et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Hydroxycinnamoyl Amino Acids Conjugates: A Chiral Pool to Distinguish Commercially Exploited Coffea spp.

(2020) Federico Berti et al.   MOLECULES

Residue-Specific Binding Mechanisms of Thioflavin T to a Surface of Flat β-Sheets within a Peptide Self-Assembly Mimic

(2020) Sae Namioka et al.   BIOCHEMISTRY

Anti-Alzheimer's flavanolignans from Ceiba pentandra aerial parts

(2020) Mohamed E. Abouelela et al.   FITOTERAPIA

Antimicrobial activity and secondary structure of a novel peptide derived from ovalbumin

(2020) Ao Tan et al.   JOURNAL OF PEPTIDE SCIENCE

Curcumin Inhibits the Primary Nucleation of Amyloid-Beta Peptide: A Molecular Dynamics Study

(2020) Irini Doytchinova et al.   Biomolecules

Irreversible incorporation of L-dopa into the C-terminus of α-tubulin inhibits binding of molecular motor KIF5B to microtubules and alters mitochondrial traffic along the axon

(2020) Agustina Zorgniotti et al.   NEUROBIOLOGY OF DISEASE

L‐DOPA regulates α‐synuclein accumulation in experimental parkinsonism

(2020) Marc Deffains et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Proline-Mediated Knoevenagel–Doebner Condensation in Ethanol: A Sustainable Access to p-Hydroxycinnamic Acids

(2019) Cédric Peyrot et al.   ACS Sustainable Chemistry & Engineering

Design, synthesis, and evaluation of a water soluble C5-monoketone type curcumin analogue as a potent amyloid β aggregation inhibitor

(2019) Mayumi Hotsumi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure-activity relationship of clovamide and its related compounds for the inhibition of amyloid β aggregation

(2018) Tatsuhiko Tsunoda et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of caffeic acid phenethyl ester derivatives as novel myeloid differentiation protein 2 inhibitors for treatment of acute lung injury

(2018) Lingfeng Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Rationally designed divalent caffeic amides inhibit amyloid-β fibrillization, induce fibril dissociation, and ameliorate cytotoxicity

(2018) Ling-Hsien Tu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Investigation for the cyclization efficiency of linear tetrapeptides: Synthesis of tentoxin B and dihydrotentoxin

(2018) Ryota Sato et al.   TETRAHEDRON

Design, synthesis and evaluation of curcumin-based fluorescent probes to detect Aβ fibrils

(2018) Taki Sato et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cytotoxic evaluation of natural and synthetic callipeltins: a revision of cytotoxicity of callipeltin B

(2016) Mari Kikuchi et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery?

(2015) Jonathan Bisson et al.   JOURNAL OF MEDICINAL CHEMISTRY

In Vitro Studies on Accelerating the Degradation and Clearance of Amyloid-β Fibrils by an Antiamyloidogenic Peptide

(2015) Qian Zhang et al.   ACS Macro Letters

Structure activity relationship study of curcumin analogues toward the amyloid-beta aggregation inhibitor

(2014) Hitoshi Endo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Natural Cinnamic Acids, Synthetic Derivatives and Hybrids with Antimicrobial Activity

(2014) Juan Guzman   MOLECULES

Synthesis and evaluation of curcumin derivatives toward an inhibitor of beta-site amyloid precursor protein cleaving enzyme 1

(2013) Hiroyuki Konno et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study

(2012) John M Ringman et al.   Alzheimers Research & Therapy

Anti-inflammatory Properties of Clovamide andTheobroma cacaoPhenolic Extracts in Human Monocytes: Evaluation of Respiratory Burst, Cytokine Release, NF-κB Activation, and PPARγ Modulation

(2011) HuaWu Zeng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Discovery of the curcumin metabolic pathway involving a unique enzyme in an intestinal microorganism

(2011) A. Hassaninasab et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clovamide and rosmarinic acid induce neuroprotective effects inin vitromodels of neuronal death

(2009) S Fallarini et al.   BRITISH JOURNAL OF PHARMACOLOGY

Flip-Flop of Phospholipids in Vesicles: Kinetic Analysis with Time-Resolved Small-Angle Neutron Scattering

(2009) Minoru Nakano et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease

(2008) A. N. Begum et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Roasting impact on the contents of clovamide (N-caffeoyl-L-DOPA) and the antioxidant activity of cocoa beans (Theobroma cacao L.)

(2007) Marco Arlorio et al.   FOOD CHEMISTRY