Review
Orthopedics
K. R. Arant, J. N. Katz, T. Neogi
Summary: This review outlines the most commonly used quantitative sensory tests to identify pain sensitization in knee osteoarthritis (OA) patients. Findings suggest that lower PPT thresholds, inefficient CPM, and facilitated TS are common in knee OA patients, and that QST measures are more closely associated with pain severity than OA radiographic severity. QST may have a role in personalized, more effective treatment of OA.
OSTEOARTHRITIS AND CARTILAGE
(2022)
Article
Biochemistry & Molecular Biology
Stefano Tozza, Daniele Severi, Giovanni Palumbo, Vincenzo Provitera, Lucia Ruggiero, Raffaele Dubbioso, Rosa Iodice, Maria Nolano, Fiore Manganelli
Summary: This study evaluated the role of QST in the multidisciplinary evaluation of late onset carriers, showing that thermal QST can serve as an important tool in detecting nerve fiber dysfunction. The study found that conducting stimulation tests on the foot and/or leg can increase the chances of detecting abnormal results, while investigating the hand can provide useful information in monitoring disease progression.
Review
Anesthesiology
Mohamed G. Sobeeh, Sherief Ghozy, Rami M. Elshazli, Marc Landry
Summary: This systematic review found that patients with carpal tunnel syndrome (CTS) exhibit sensory loss, increased thermal and mechanical pain sensitivity, and impaired conditioned pain modulation. However, the evidence for central sensitization in CTS remains inconclusive.
Article
Anesthesiology
R. Norman Harden, Candida S. McCabe, Andreas Goebel, Michael Massey, Tolga Suvar, Sharon Grieve, Stephen Bruehl
Summary: There have been modest advancements in Complex Regional Pain Syndrome research, but the overall quantity and quality of work in this field remains low. The rarity of the disease makes it difficult to gather a sufficient sample size for statistical significance using traditional approaches. However, researchers are using semi-systematic reviews and including data from various sources to tailor treatment regimes for patients.
Article
Anesthesiology
Matthew J. Kmiecik, Frank F. Tu, Daniel J. Clauw, Kevin M. Hellman
Summary: Multimodal hypersensitivity (MMH), characterized by increased sensitivity across multiple sensory modalities, is associated with the development of chronic pain. This study examined a cohort of women and found that MMH was a significant predictor of pelvic pain, even after adjusting for baseline pain levels. These findings suggest that MMH may play a crucial role in the long-term risk and development of pelvic pain.
Article
Dentistry, Oral Surgery & Medicine
Anne Wolowski, N. Schwarzbach, H. Hoerning
Summary: Patients with burning mouth syndrome show altered thermal sensitivity and pain thresholds compared to healthy controls, indicating a dysfunction in both the peripheral and central nervous systems in processing pain.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Oncology
W. Iris Zhi, Raymond E. Baser, Dristi Talukder, Ying Zi Mei, Steven E. Harte, Ting Bao
Summary: This study investigated the effects of acupuncture on chemotherapy-induced peripheral neuropathy (CIPN) using semi-objective quantitative sensory testing (QST). The results showed that both real acupuncture and sham acupuncture significantly improved certain sensory functions in CIPN patients, particularly in terms of vibrational detection in the feet and cool thermal detection in the hands.
BREAST CANCER RESEARCH AND TREATMENT
(2023)
Review
Orthopedics
Mohamed Gomaa Sobeeh, Karima Abdelaty Hassan, Anabela Goncalves da Silva, Enas Fawzy Youssef, Nadia Abdelazim Fayaz, Maha Mostafa Mohammed
Summary: This review aimed to understand the sensory phenotype of complex regional pain syndrome (CRPS) and guide treatment strategies based on quantitative sensory testing (QST). The results showed that adults with CRPS experience significant loss of thermal, mechanical, and vibration sensations, as well as increased pain thresholds and ratings. Adolescents and children with CRPS have milder sensory abnormalities compared to adults. These findings are important for understanding the pain mechanisms of CRPS and guiding treatment.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Veterinary Sciences
Kata Orsolya Veres-Nyeki, Jozsef Nyeki, Gabor Bodo, Claudia Spadavecchia
Summary: This experimental study aimed to define the tactile sensory, mechanical nociceptive, and thermal nociceptive thresholds of the equine face. The study found that all thresholds increased with age, while sex had no effect on thresholds. Stimulation site affected tactile sensory and mechanical nociceptive thresholds, but not thermal nociceptive threshold.Shaving had no significant effect on any of the thresholds.
EQUINE VETERINARY JOURNAL
(2021)
Article
Anesthesiology
Emily Moore, Felicity A. Braithwaite, Tasha R. Stanton, Valeria Bellan, G. Lorimer Moseley, Carolyn Berryman
Summary: This study identified 48 core concepts, rated as 'very important', for the educational content related to Complex Regional Pain Syndrome (CRPS) by both individuals with CRPS and advanced practitioner healthcare professionals. These concepts highlight the importance of understanding and evidence-based management of the condition, as well as self-management strategies, pacing, and movement.
EUROPEAN JOURNAL OF PAIN
(2022)
Article
Multidisciplinary Sciences
Salvatore Crisafulli, Andrea Fontana, Luca L'Abbate, Valentina Ientile, Daniele Gianfrilli, Alessia Cozzolino, Maria Cristina De Martino, Marta Ragonese, Janet Sultana, Francesco Barone-Adesi, Gianluca Trifiro
Summary: This study aimed to compare and measure the accuracy of newly and previously developed coding algorithms for identifying acromegaly using Italian claims databases. Four algorithms were used to detect acromegaly cases from the general population, based on combinations of diagnostic, surgical procedure, and co-payment exemption codes, pharmacy claims, and specialist visits. The best algorithm achieved high sensitivity and Youden Index.
SCIENTIFIC REPORTS
(2022)
Article
Nutrition & Dietetics
Mingguang Yu, Chengdong Zheng, Qinggang Xie, Yuan Tang, Ying Wang, Baosong Wang, Huanlu Song, Yalin Zhou, Yajun Xu, Rongqiang Yang
Summary: In this study, a three-tiered human milk flavor wheel was constructed based on 53 sensory descriptors. The established sensory descriptors could properly reflect the general sensory properties of human milk and could be used to distinguish different samples. Further investigation found that fat content might be an important factor influencing the sensory properties of human milk.
Article
Anesthesiology
Donna L. Kennedy, Jan Vollert, Deborah Ridout, Caroline M. Alexander, Andrew S. C. Rice
Summary: The DFNS quantitative sensory testing method can effectively identify changes in sensory phenotype in patients with entrapment neuropathy, which are closely related to symptom changes after clinical interventions. In an entrapment neuropathy model, sensory phenotype is independent of disease severity and may reflect the underlying neuropathophysiology.
Article
Agriculture, Multidisciplinary
Yingxia He, Ke Tang, Xiaowei Yu, Shuang Chen, Yan Xu
Summary: The study found that esters are the main compounds contributing to the pungency of Baijiu, while aldehydes and acids have a lesser impact on pungency. This information provides a useful basis for improving the quality of distilled spirits in the future.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Review
Clinical Neurology
Matthias Braun, Corina Bello, Thomas Riva, Christian Hoenemann, Dietrich Doll, Richard D. Urman, Markus M. Luedi
Summary: Quantitative sensory testing (QST) shows high relevance in predicting acute and chronic postoperative pain, especially in patients undergoing orthopedic procedures. By implementing QST testing, patients at risk can be identified and proactive preventive management measures can be taken, advancing traditional pain therapy towards personalized perioperative pain medicine.
CURRENT PAIN AND HEADACHE REPORTS
(2021)
Review
Rehabilitation
Hilma Caravau, Ana Filipa Rosa, Nelson P. Rocha, Anabela G. Silva
Summary: This systematic literature review examines the methodological quality of pain assessment instruments in individuals with cerebral palsy. The study finds limited and low-quality evidence for the measurement properties of these instruments. Further research is needed following the COSMIN recommendations.
DISABILITY AND REHABILITATION
(2022)
Article
Health Care Sciences & Services
Rosa Andias, Anabela G. Silva
Summary: In adolescents with chronic neck pain, female gender and symptoms of central sensitization at baseline were positively associated with pain persistence at 6-month follow-up. Disability and symptoms of central sensitization at baseline were positively associated with disability persistence.
QUALITY OF LIFE RESEARCH
(2022)
Article
Rheumatology
Joana Marques, Lauta Borges, Rosa Andias, Anabela G. Silva
Summary: This study evaluated commonly downloaded apps targeting neck pain, finding that these apps generally have acceptable quality, focus on exercise, but lack educational components. User ratings in app stores are not indicative of app quality.
MUSCULOSKELETAL CARE
(2022)
Article
Orthopedics
Rosa Andias, Anabela Goncalves Silva
Summary: This study investigated the association between sociodemographic data, physical activity, depression, anxiety, stress, sleep, self-reported symptoms of central sensitization, and the onset of pain in asymptomatic adolescents. The results showed that being female and having more self-reported symptoms of central sensitization were associated with the onset of chronic pain at follow-up.
Article
Anesthesiology
Rosa Andias, Anabela G. Silva
Summary: This study explores and compares the associations between psychosocial factors, sleep, and central sensitization with chronic neck, back, limb, and multiregional pain and disability. The results show that there are similar but also different variables associated with the presence of pain and disability in different body regions.
Review
Multidisciplinary Sciences
Frederico Mesquita Baptista, Eduardo Brazete Cruz, Vera Afreixo, Anabela G. Silva
Summary: Recent studies have shown that musculoskeletal conditions have a significant impact on the global population in terms of disability. Pain and functional disability are the main challenges faced by individuals with these conditions. Neural mobilization has been proven to be an effective intervention for musculoskeletal pain and can improve functionality. However, systematic reviews in recent years have varied in methodology and conclusions. This document outlines a planned protocol for a comprehensive systematic review with meta-analysis to review the up-to-date evidence on the use of neural mobilization in managing musculoskeletal pain disorders.
Article
Environmental Sciences
Javier Dorado Chaparro, Jesus Fernandez-Bermejo Ruiz, Maria Jose Santofimia Romero, Xavier del Toro Garcia, Ruben Cantarero Navarro, Cristina Bolanos Peno, Henry Llumiguano Solano, Felix Jesus Villanueva Molina, Anabela Goncalves Silva, Juan Carlos Lopez
Summary: While physical activity is important for older adults, there are barriers limiting their access to exercise. The study found that utility and usability are key factors for user acceptance of technology. In addition, the needs of other stakeholders should be considered in the development of technologies to support physical activity in older adults.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Rheumatology
Francisco M. F. Nogueira, Ricardo P. Martins, Ellen C. H. Pereira Nery, Anabela G. Silva
Summary: The incidence of knee pain in adults has been increasing, and smartphone and mobile applications may help in the rehabilitation process. However, the quality of current free mobile apps targeting knee pain needs improvement to increase engagement and usage. Involvement of health professionals during the development process is important to ensure evidence-based content and progression recommendations.
MUSCULOSKELETAL CARE
(2023)
Review
Anesthesiology
Ellen C. H. Pereira Nery, Nelson P. Rocha, Vitor T. Cruz, Anabela G. Silva
Summary: This study aimed to assess the association between idiopathic chronic low back pain and cognitive function. The researchers found that individuals with low back pain had impaired cognitive function in problem solving, information processing, working memory, and delayed memory. The association between pain characteristics, psychological factors, and cognitive function was inconclusive. More research is needed to explore these associations and improve evidence in this field.
Article
Health Care Sciences & Services
Ana Isabel Martins, Goncalo Santinha, Ana Margarida Almeida, Oscar Ribeiro, Telmo Silva, Nelson Rocha, Anabela G. Silva
Summary: This study aimed to generate consensus on terms and procedures for usability evaluation of health-related digital solutions by users and experts. A Delphi study was conducted to gather input from experienced international participants. Consensus was achieved on definitions and a checklist was proposed to guide the planning and reporting of usability studies. This study is an important step towards standardizing usability evaluation and enhancing the quality of usability studies.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Rehabilitation
Helena Pinho, Marcia Neves, Fabiola Costa, Anabela G. Silva
Summary: This study found that high-intensity interval aerobic exercise does not significantly affect pain intensity or pain sensitivity in patients with chronic non-specific low back pain, compared to moderate-intensity continuous aerobic exercise and no exercise. Therefore, high-intensity interval aerobic exercise can be used in clinical practice and patients can be reassured that it is unlikely to increase pain.
MUSCULOSKELETAL SCIENCE AND PRACTICE
(2023)
Article
Health Care Sciences & Services
Ceci Diehl, Ana Martins, Ana Almeida, Telmo Silva, Oscar Ribeiro, Goncalo Santinha, Nelson Rocha, Anabela G. Silva
Summary: This study aims to analyze and synthesize existing user interface design recommendations and propose a practical set of recommendations that guide the development of different technologies.
JMIR HUMAN FACTORS
(2022)
Article
Rehabilitation
Pollyanna Stefane, Laetitia Teixeira, Oscar Ribeiro, Anabela G. Silva
Summary: The study found that only a small percentage of older adults self-refer to physiotherapy, with those of higher income and education levels more likely to have direct access to physiotherapy. This suggests the need to improve public health systems, health insurance, and campaigns promoting physiotherapy targeting older adults.
EUROPEAN JOURNAL OF PHYSIOTHERAPY
(2022)
