Developmental plasticity shapes synaptic phenotypes of autism-associated neuroligin-3 mutations in the calyx of Held

Temporal patterns of gene expression during calyx of held development

(2015) Douglas R. Kolson et al.   Developmental Neurobiology

Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor trafficking

(2015) S Chanda et al.   MOLECULAR PSYCHIATRY

Conditional neuroligin-2 knockout in adult medial prefrontal cortex links chronic changes in synaptic inhibition to cognitive impairments

(2015) J Liang et al.   MOLECULAR PSYCHIATRY

Ephrin-A2 and ephrin-A5 guide contralateral targeting but not topographic mapping of ventral cochlear nucleus axons

(2015) Mariam L. Abdul-latif et al.   Neural Development

RIM-BPs Mediate Tight Coupling of Action Potentials to Ca 2+ -Triggered Neurotransmitter Release

(2015) Claudio Acuna et al.   NEURON

Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses

(2015) Bo Zhang et al.   NEURON

Strength and precision of neurotransmission at mammalian presynaptic terminals

(2015) Tomoyuki TAKAHASHI   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Autism-Associated Neuroligin-3 Mutations Commonly Impair Striatal Circuits to Boost Repetitive Behaviors

(2014) Patrick E. Rothwell et al.   CELL

Morphological and physiological development of auditory synapses

(2014) Wei-Ming Yu et al.   HEARING RESEARCH

De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability

(2014) S E McCarthy et al.   MOLECULAR PSYCHIATRY

SAD kinases control the maturation of nerve terminals in the mammalian peripheral and central nervous systems

(2014) B. N. Lilley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Genetic Landscapes of Autism Spectrum Disorders

(2013) Guillaume Huguet et al.   Annual Review of Genomics and Human Genetics

Presynaptic Neurexin-3 Alternative Splicing trans-Synaptically Controls Postsynaptic AMPA Receptor Trafficking

(2013) Jason Aoto et al.   CELL

The emerging role ofSHANKgenes in neuropsychiatric disorders

(2013) Audrey Guilmatre et al.   Developmental Neurobiology

Synaptic Inputs Compete during Rapid Formation of the Calyx of Held: A New Model System for Neural Development

(2013) P. S. Holcomb et al.   JOURNAL OF NEUROSCIENCE

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

(2013)   LANCET

Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders

(2013) E M Kenny et al.   MOLECULAR PSYCHIATRY

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

(2013) S Hong Lee et al.   NATURE GENETICS

BMP signaling specifies the development of a large and fast CNS synapse

(2013) Le Xiao et al.   NATURE NEUROSCIENCE

Robo3-Driven Axon Midline Crossing Conditions Functional Maturation of a Large Commissural Synapse

(2013) Nicolas Michalski et al.   NEURON

Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling

(2013) Csaba Földy et al.   NEURON

Neuroligin 2 Is Expressed in Synapses Established by Cholinergic Cells in the Mouse Brain

(2013) Virág T. Takács et al.   PLoS One

Erratum: Pathogenetic model for Tourette syndrome delineates overlap with related neurodevelopmental disorders including Autism

(2012) R A Clarke et al.   Translational Psychiatry

Copy Number Variants in Schizophrenia: Confirmation of Five Previous Findings and New Evidence for 3q29 Microdeletions and VIPR2 Duplications

(2011) Douglas F. Levinson et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genome-Wide Analysis of Copy Number Variants in Attention Deficit Hyperactivity Disorder: The Role of Rare Variants and Duplications at 15q13.3

(2011) Nigel M. Williams et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Calyx of Held Synapse: From Model Synapse to Auditory Relay

(2011) J. Gerard G. Borst et al.   Annual Review of Physiology

Cbln1 and its family proteins in synapse formation and maintenance

(2011) Michisuke Yuzaki   CURRENT OPINION IN NEUROBIOLOGY

An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus

(2011) Mark R Etherton et al.   EMBO JOURNAL

Action potential bursts enhance transmitter release at a giant central synapse

(2011) Bo Zhang et al.   JOURNAL OF PHYSIOLOGY-LONDON

GluA4 is indispensable for driving fast neurotransmission across a high-fidelity central synapse

(2011) Yi-Mei Yang et al.   JOURNAL OF PHYSIOLOGY-LONDON

RIM Determines Ca2+ Channel Density and Vesicle Docking at the Presynaptic Active Zone

(2011) Yunyun Han et al.   NEURON

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

(2011) Dan Levy et al.   NEURON

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

(2011) Stephan J. Sanders et al.   NEURON

Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina

(2011) M. Hoon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function

(2011) M. Etherton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Genetics of Autism Spectrum Disorders and Related Neuropsychiatric Disorders in Childhood

(2010) Paul Lichtenstein et al.   AMERICAN JOURNAL OF PSYCHIATRY

Is schizophrenia on the autism spectrum?

(2010) Bryan H. King et al.   BRAIN RESEARCH

Trans-Synaptic Interaction of GluRδ2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum

(2010) Takeshi Uemura et al.   CELL

Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder

(2010) Nanda N. J. Rommelse et al.   EUROPEAN CHILD & ADOLESCENT PSYCHIATRY

Formation and maturation of the calyx of Held

(2010) Paul A. Nakamura et al.   HEARING RESEARCH

LRRTMs and Neuroligins Bind Neurexins with a Differential Code to Cooperate in Glutamate Synapse Development

(2010) T. J. Siddiqui et al.   JOURNAL OF NEUROSCIENCE

Septins Regulate Developmental Switching from Microdomain to Nanodomain Coupling of Ca2+ Influx to Neurotransmitter Release at a Central Synapse

(2010) Yi-Mei Yang et al.   NEURON

Cbln1 Is a Ligand for an Orphan Glutamate Receptor  2, a Bidirectional Synapse Organizer

(2010) K. Matsuda et al.   SCIENCE

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

(2009) Paul Lichtenstein et al.   LANCET

Action potential evoked transmitter release in central synapses: insights from the developing calyx of Held

(2009) Lu-Yang Wang et al.   Molecular Brain

Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample

(2008) Angelica Ronald et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Autism Spectrum Disorders and Childhood-Onset Schizophrenia: Clinical and Biological Contributions to a Relation Revisited

(2008) Judith Rapoport et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE