Somatic mutation detection using various targeted detection assays in paired samples of circulating tumor DNA, primary tumor and metastases from patients undergoing resection of colorectal liver metastases

Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care

(2016) S. El Messaoudi et al.   CLINICAL CANCER RESEARCH

Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen

(2016) Maurice P.H.M. Jansen et al.   Oncotarget

Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer

(2015) J. Tie et al.   ANNALS OF ONCOLOGY

Prognostic value of circulating tumour cells for early recurrence after resection of colorectal liver metastases

(2015) Z S Lalmahomed et al.   BRITISH JOURNAL OF CANCER

Serial Next-Generation Sequencing of Circulating Cell-Free DNA Evaluating Tumor Clone Response To Molecularly Targeted Drug Administration

(2015) J. S. Frenel et al.   CLINICAL CANCER RESEARCH

Discriminating somatic and germline mutations in tumor DNA samples without matching normals

(2015) Saskia Hiltemann et al.   GENOME RESEARCH

Analysis of circulating tumour DNA to monitor disease burden following colorectal cancer surgery

(2015) Thomas Reinert et al.   GUT

Analysis of circulating DNA and protein biomarkers to predict the clinical activity of regorafenib and assess prognosis in patients with metastatic colorectal cancer: a retrospective, exploratory analysis of the CORRECT trial

(2015) Josep Tabernero et al.   LANCET ONCOLOGY

mRNA expression profiles in circulating tumor cells of metastatic colorectal cancer patients

(2015) Bianca Mostert et al.   Molecular Oncology

Erratum: Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients

(2015) Giulia Siravegna et al.   NATURE MEDICINE

Mutation profiling of tumor DNA from plasma and tumor tissue of colorectal cancer patients with a novel, high-sensitivity multiplexed mutation detection platform

(2015) Evelyn Kidess et al.   Oncotarget

Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil-DNA glycosylase.

(2015) Hongdo Do et al.   Oncotarget

Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analysis in breast cancer

(2014) F. Rothé et al.   ANNALS OF ONCOLOGY

Noninvasive Diagnosis of Actionable Mutations by Deep Sequencing of Circulating Free DNA in Lung Cancer from Never-Smokers: A Proof-of-Concept Study from BioCAST/IFCT-1002

(2014) S. Couraud et al.   CLINICAL CANCER RESEARCH

Mutants TP53 p.R273H and p.R273C but not p.R273G Enhance Cancer Cell Malignancy

(2014) Jie Li et al.   HUMAN MUTATION

Liquid Biopsies: Genotyping Circulating Tumor DNA

(2014) Luis A. Diaz et al.   JOURNAL OF CLINICAL ONCOLOGY

Primary and acquired resistance to EGFR-targeted therapies in colorectal cancer: impact on future treatment strategies

(2014) Simonetta M. Leto et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Circulating tumor DNA as a non-invasive substitute to metastasis biopsy for tumor genotyping and personalized medicine in a prospective trial across all tumor types

(2014) Ronald Lebofsky et al.   Molecular Oncology

Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA

(2014) Alain R Thierry et al.   NATURE MEDICINE

Comparative Genomic Analysis of Primary and Synchronous Metastatic Colorectal Cancers

(2014) Sun Young Lee et al.   PLoS One

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Circulating Cell-Free DNA from Colorectal Cancer Patients May Reveal High KRAS or BRAF Mutation Load

(2014) Florent Mouliere et al.   Translational Oncology

Blood-Based Analyses of Cancer: Circulating Tumor Cells and Circulating Tumor DNA

(2014) D. A. Haber et al.   Cancer Discovery

A stabilizing reagent prevents cell-free DNA contamination by cellular DNA in plasma during blood sample storage and shipping as determined by digital PCR

(2013) S.E. Norton et al.   CLINICAL BIOCHEMISTRY

Reducing Sequence Artifacts in Amplicon-Based Massively Parallel Sequencing of Formalin-Fixed Paraffin-Embedded DNA by Enzymatic Depletion of Uracil-Containing Templates

(2013) H. Do et al.   CLINICAL CHEMISTRY

Circulating Tumor DNA to Monitor Metastatic Breast Cancer

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Genetic heterogeneity and cancer drug resistance

(2012) Nicholas C Turner et al.   LANCET ONCOLOGY

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

(2012) Sandra Misale et al.   NATURE

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Winnowing DNA for Rare Sequences: Highly Specific Sequence and Methylation Based Enrichment

(2012) Jason D. Thompson et al.   PLoS One

The Evolving War on Cancer

(2011) Daniel A. Haber et al.   CELL

Quantifying EGFR Alterations in the Lung Cancer Genome with Nanofluidic Digital PCR Arrays

(2010) J. Wang et al.   CLINICAL CHEMISTRY

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

(2010) Wendy De Roock et al.   LANCET ONCOLOGY

Circulating mutant DNA to assess tumor dynamics

(2008) Frank Diehl et al.   NATURE MEDICINE