Article
Clinical Neurology
Gen Li, Pei Huang, Shishuang Cui, Yachao He, Yuyan Tan, Shengdi Chen
Summary: Long-term Tai Chi training in patients with Parkinson's disease showed maintenance of improvement in motor and non-motor symptoms, reducing the need for increasing antiparkinsonian therapies. The annual increase in levodopa equivalent daily dosage was significantly lower in the Tai Chi group, indicating the benefits of Tai Chi training on PD symptoms and complications.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Review
Neurosciences
Max A. Little
Summary: Parkinson's disease is complex and diverse, with gaps in scientific understanding. Smartphones can capture behavioral signals remotely, and computational algorithms can analyze metrics of symptom severity and progression. Future prospects for this technology include exploring experimental, hardware, and software logistics.
JOURNAL OF PARKINSONS DISEASE
(2021)
Article
Geriatrics & Gerontology
Eva Ntanasi, Maria Maraki, Mary Yannakoulia, Maria Stamelou, Georgia Xiromerisiou, Mary H. Kosmidis, Efthimios Dardiotis, Georgios Hadjigeorgiou, Paraskevi Sakka, Antonios Gargalionis, Kostas Patas, Stylianos Chatzipanagiotou, Socrates Charisis, Leonidas Stefanis, Nikolaos Scarmeas
Summary: The study found an association between frailty and prodromal PD and PD, suggesting that frailty may impact the likelihood of older individuals developing these conditions, and indicating common characteristics or underlying mechanisms among them.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Article
Neurosciences
Clara Virbel-Fleischman, Flavien Mousin, Shuo Liu, Sebastien Hardy, Jean-Christophe Corvol, Isabelle Benatru, David Bendetowicz, Matthieu Bereau, Valerie Cochen De Cock, Sophie Drapier, Solene Frismand, Caroline Giordana, David Devos, Yann Retory, David Grabli
Summary: Body-worn sensors can provide valuable information for the management of Parkinson's disease and support treatment decisions based on objective monitoring. This study found a correlation between monitoring results and treatment adaptations, suggesting the potential for automated treatment modifications based on sensor recordings.
NPJ PARKINSONS DISEASE
(2023)
Article
Clinical Neurology
Ana Marques, Bruno Pereira, Michela Figorilli, Tiphaine Vidal, Paul Deffarges, Franck Durif, Livia Fantini
Summary: This study aimed to assess decision-making abilities in Parkinson's disease patients with coexisting REM sleep behavior disorder (RBD). The results revealed impaired decision-making in PD-RBD compared to PD-nRBD and healthy controls, which may explain the increased risk of developing impulse control disorders in these patients.
Article
Chemistry, Analytical
Mehar Singh, Prithvi Prakash, Rachneet Kaur, Richard Sowers, James Robert Brasic, Manuel Enrique Hernandez
Summary: Wearable sensors combined with deep learning approaches can be used to assess the severity of motor impairment in Parkinson's disease. By incorporating motion data from healthy older adults and utilizing unsupervised pre-training, the classification performance can be improved. Learning from healthy older adults' motion data can enhance the representation of Parkinson's disease motion data for motor impairment classification.
Review
Clinical Neurology
S. M. Cartella, C. Terranova, V. Rizzo, A. Quartarone, P. Girlanda
Summary: The article discusses the relationship between Covid-19 and Parkinson's Disease, focusing on five aspects: the increased risk of severe Covid-19 infection for frail, old, multi-pathological patients; the impact on PD patients' health and risk of developing severe Covid-19; the consequences of lockdown and restrictive measures on mental and cognitive health of patients and caregivers; considerations for patient care and management during this unprecedented time; and the possibility of Covid-19-induced parkinsonism.
JOURNAL OF NEUROLOGY
(2021)
Article
Health Care Sciences & Services
Valentina Varalta, Paola Poiese, Serena Recchia, Barbara Montagnana, Cristina Fonte, Mirko Filippetti, Michele Tinazzi, Nicola Smania, Alessandro Picelli
Summary: This study investigated the effects of consecutive physiotherapy and cognitive rehabilitation on cognitive, motor, and psychological aspects in Parkinson's disease patients. Results showed that patients who received consecutive training performed better in functional mobility and memory tasks, supporting the hypothesis that consecutive physiotherapy plus cognitive rehabilitation may be more beneficial than physiotherapy alone.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Clinical Neurology
Vasiliki Bougou, Michael Vanhoyland, Thomas Decramer, Anais Van Hoylandt, Steven Smeijers, Bart Nuttin, Philippe De Vloo, Wim Vandenberghe, Alice Nieuwboer, Peter Janssen, Tom Theys
Summary: This study investigated the neural activity changes during cycling in patients with Parkinson's disease. The results showed that both active and passive cycling caused suppression of beta activity, while active cycling also led to stronger high gamma band activity. Furthermore, patients with freezing of gait exhibited stronger beta suppression during passive cycling.
MOVEMENT DISORDERS
(2023)
Article
Multidisciplinary Sciences
Zhaoying Dong, Rui Zuo, Xiaoni Zhong, Changhong Zhang, Xiaoya Zou, Yuan Tian, Hongzhou Zuo, Xinyi Du, Qian Yu, Oumei Cheng
Summary: There is no evidence that antihypertensive drugs can delay the progression of Parkinson's disease within 2 years.
Article
Pediatrics
Adriana Prato, Federica Saia, Maria Chiara Milana, Miriam Scerbo, Rita Barone, Renata Rizzo
Summary: This study explores the characteristics and course of newly diagnosed functional tic-like behaviors. It was found that there was an increase in functional tic-like behaviors in vulnerable children and adolescents after social media exposure during the COVID-19 pandemic. The results showed significant variations in the severity of tics and anxiety symptoms among patients with functional tic-like behaviors.
FRONTIERS IN PEDIATRICS
(2023)
Article
Plant Sciences
Qiuran Wang, Silvia Guerra, Bianca Bonato, Valentina Simonetti, Maria Bulgheroni, Umberto Castiello
Summary: Finding a suitable support is crucial for climbing plants, as it affects their performance and fitness. Previous studies have focused on the mechanistic details of support-searching and attachment, while fewer have considered the ecological significance and influencing factors. This study investigates the influence of support diameter on pea plants' movement and reveals a preference for thinner supports. These findings shed further light on how climbing plants make decisions regarding support-searching and demonstrate their ability to adapt to environmental scenarios.
Article
Health Care Sciences & Services
Malte L. Schmieding, Marvin Kopka, Konrad Schmidt, Sven Schulz-Niethammer, Felix Balzer, Markus A. Feufel
Summary: Symptom checkers, digital tools that assist laypersons in self-assessing medical complaints, have not shown improvement in triage accuracy over the past five years, with some even declining in their ability to accurately determine the need for emergency care or self-care. Further research is needed to continuously evaluate and provide guidance on the use of symptom checkers.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Clinical Neurology
He Zhou, Hung Nguyen, Ana Enriquez, Louie Morsy, Michael Curtis, Timothy Piser, Christopher Kenney, Christopher D. Stephen, Anoopum S. Gupta, Jeremy D. Schmahmann, Ashkan Vaziri
Summary: The study utilized wearable sensors to objectively measure motor impairment in SCA patients during gait and balance assessments, distinguishing them from healthy controls. Linear regression models demonstrated moderate-to-strong correlation with SARA and BARS2 scores.
NEUROLOGICAL SCIENCES
(2022)
Article
Orthopedics
Judith E. Deutsch, Kathleen M. Gill-Body, Margaret Schenkman
Summary: The updated Integrated Framework for Clinical Decision Making responds to changes in evidence, policy, and practice, and applies to individuals of all ages and health conditions. It emphasizes shared decision-making, patient-centered care, and integrates movement science and International Classification of Function language into patient management, serving as a guide for clinical practice and physical therapist education.
