DAT1 and BDNF polymorphisms interact to predict Aβ and tau pathology

New perspectives on the basal forebrain cholinergic system in Alzheimer’s disease

(2023) Anne S. Berry et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Associations among locus coeruleus catecholamines, tau pathology, and memory in aging

(2022) Claire J. Ciampa et al.   NEUROPSYCHOPHARMACOLOGY

BDNF-Met polymorphism and amyloid-beta in relation to cognitive decline in cognitively normal elderly: the SCIENCe project

(2021) Karlijn A. van den Bosch et al.   NEUROBIOLOGY OF AGING

The Alzheimer’s disease drug development landscape

(2021) Pieter van Bokhoven et al.   Alzheimers Research & Therapy

Predicting future rates of tau accumulation on PET

(2020) Clifford R Jack et al.   BRAIN

Interaction Between BDNF Val66Met and APOE4 on Biomarkers of Alzheimer’s Disease and Cognitive Decline

(2020) Cynthia M. Stonnington et al.   JOURNAL OF ALZHEIMERS DISEASE

The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer’s disease

(2019) Nicolai Franzmeier et al.   MOLECULAR PSYCHIATRY

The Influence of Hippocampal Dopamine D2 Receptors on Episodic Memory Is Modulated by BDNF and KIBRA Polymorphisms

(2019) Goran Papenberg et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Alzheimer’s disease pathology: pathways between central norepinephrine activity, memory, and neuropsychiatric symptoms

(2019) Heidi I. L. Jacobs et al.   MOLECULAR PSYCHIATRY

Brain-derived neurotrophic factor (BDNF) and TrkB hippocampal gene expression are putative predictors of neuritic plaque and neurofibrillary tangle pathology

(2019) Stephen D. Ginsberg et al.   NEUROBIOLOGY OF DISEASE

Interactive effects of dopamine transporter genotype and aging on resting-state functional networks

(2019) Christian Baeuchl et al.   PLoS One

Tau seeding activity begins in the transentorhinal/entorhinal regions and anticipates phospho-tau pathology in Alzheimer’s disease and PART

(2018) Sarah K. Kaufman et al.   ACTA NEUROPATHOLOGICA

The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease

(2018) Harald Hampel et al.   BRAIN

BDNF Val66Met in preclinical Alzheimer's disease is associated with short-term changes in episodic memory and hippocampal volume but not serum mBDNF

(2017) Yen Ying Lim et al.   INTERNATIONAL PSYCHOGERIATRICS

Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease

(2017) Annalisa Nobili et al.   Nature Communications

BDNFVal66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer’s disease

(2016) Yen Ying Lim et al.   BRAIN

Neuronal activity enhances tau propagation and tau pathology in vivo

(2016) Jessica W Wu et al.   NATURE NEUROSCIENCE

Dopamine agonists rescue Aβ–induced LTP impairment by Src-family tyrosine kinases

(2016) PingAn Yuan Xiang et al.   NEUROBIOLOGY OF AGING

Higher brainBDNFgene expression is associated with slower cognitive decline in older adults

(2016) Aron S. Buchman et al.   NEUROLOGY

Carriers of a common variant in the dopamine transporter gene have greater dementia risk, cognitive decline, and faster ventricular expansion

(2015) Florence F. Roussotte et al.   Alzheimers & Dementia

MPTP-induced changes in hippocampal synaptic plasticity and memory are prevented by memantine through the BDNF-TrkB pathway

(2015) Guoqi Zhu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cross-sectional versus longitudinal estimates of age-related changes in the adult brain: overlaps and discrepancies

(2015) Adolf Pfefferbaum et al.   NEUROBIOLOGY OF AGING

Association of BDNF and BCHE with Alzheimer's disease: Meta-analysis based on 56 genetic case-control studies of 12,563 cases and 12,622 controls

(2015) HUIHUI JI et al.   Experimental and Therapeutic Medicine

APOE and BDNF Val66Met polymorphisms combine to influence episodic memory function in older adults

(2014) David D. Ward et al.   BEHAVIOURAL BRAIN RESEARCH

Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain

(2014) André Jerónimo-Santos et al.   CEREBRAL CORTEX

The Preclinical Alzheimer Cognitive Composite

(2014) Michael C. Donohue et al.   JAMA Neurology

Expression of full-length and truncated trkB in human striatum and substantia nigra neurons: implications for Parkinson’s disease

(2013) Mark E. Fenner et al.   JOURNAL OF MOLECULAR HISTOLOGY

BDNF Val66Met, Aβ amyloid, and cognitive decline in preclinical Alzheimer's disease

(2013) Yen Ying Lim et al.   NEUROBIOLOGY OF AGING

Mechanisms of dopamine transporter regulation in normal and disease states

(2013) Roxanne A. Vaughan et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Polymorphism of brain derived neurotrophic factor influences β amyloid load in cognitively intact apolipoprotein E ε4 carriers

(2013) Katarzyna Adamczuk et al.   NeuroImage-Clinical

Development and assessment of a composite score for memory in the Alzheimer’s Disease Neuroimaging Initiative (ADNI)

(2012) Paul K. Crane et al.   Brain Imaging and Behavior

A composite score for executive functioning, validated in Alzheimer’s Disease Neuroimaging Initiative (ADNI) participants with baseline mild cognitive impairment

(2012) Laura E. Gibbons et al.   Brain Imaging and Behavior

Genetic effects on behavior are mediated by neurotransmitters and large-scale neural networks

(2012) Linh C. Dang et al.   NEUROIMAGE

The Brain-Derived Neurotrophic Factor Val66Met Polymorphism and Prediction of Neural Risk for Alzheimer Disease

(2011) Aristotle N. Voineskos et al.   ARCHIVES OF GENERAL PSYCHIATRY

Neuronal activity regulates the regional vulnerability to amyloid-β deposition

(2011) Adam W Bero et al.   NATURE NEUROSCIENCE

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Activation of D1/D5 Dopamine Receptors Protects Neurons from Synapse Dysfunction Induced by Amyloid-β Oligomers

(2010) Sofia Jürgensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dopamine Controls Persistence of Long-Term Memory Storage

(2009) J. I. Rossato et al.   SCIENCE