Tau mutant A152T, a risk factor for FTD/PSP, induces neuronal dysfunction and reduced lifespan independently of aggregation in a C. elegans Tauopathy model

Evidence that Non-Fibrillar Tau Causes Pathology Linked to Neurodegeneration and Behavioral Impairments

(2017) Kurt R. Brunden et al.   JOURNAL OF ALZHEIMERS DISEASE

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

(2015) Dirk M. Walther et al.   CELL

Oligomer Formation of Tau Protein Hyperphosphorylated in Cells

(2014) Katharina Tepper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired mitochondrial respiration promotes dendritic branching via the AMPK signaling pathway

(2014) A Gioran et al.   Cell Death & Disease

Loss of MEC-17 Leads to Microtubule Instability and Axonal Degeneration

(2014) Brent Neumann et al.   Cell Reports

Worming forward: amyotrophic lateral sclerosis toxicity mechanisms and genetic interactions in Caenorhabditis elegans

(2014) Martine Therrien et al.   Frontiers in Genetics

Use of Caenorhabditis elegans as a model to study Alzheimer’s disease and other neurodegenerative diseases

(2014) Adanna G. Alexander et al.   Frontiers in Genetics

Neurodegenerative Disease Phenotypes in Carriers of MAPT p.A152T, A Risk Factor for Frontotemporal Dementia Spectrum Disorders and Alzheimer Disease

(2013) Suzee E. Lee et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration

(2013) E.-M. Mandelkow et al.   Cold Spring Harbor Perspectives in Medicine

Single/low-copy integration of transgenes in Caenorhabditis elegans using an ultraviolet trimethylpsoralen method

(2012) Eriko Kage-Nakadai et al.   BMC BIOTECHNOLOGY

Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

(2012) Giovanni Coppola et al.   HUMAN MOLECULAR GENETICS

Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity

(2012) Chronis Fatouros et al.   HUMAN MOLECULAR GENETICS

Neurite Sprouting and Synapse Deterioration in the Aging Caenorhabditis elegans Nervous System

(2012) M. L. Toth et al.   JOURNAL OF NEUROSCIENCE

The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological features

(2012) Eleanna Kara et al.   NEUROBIOLOGY OF AGING

Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions

(2011) Heidi Olzscha et al.   CELL

Unclassifiable tauopathy associated with an A152T variation in MAPT exon 7

(2011) G.G. Kovacs et al.   CLINICAL NEUROPATHOLOGY

The frontotemporal dementia mutation R406W blocks tau’s interaction with the membrane in an annexin A2–dependent manner

(2011) Anne Gauthier-Kemper et al.   JOURNAL OF CELL BIOLOGY

Spontaneous Age-Related Neurite Branching in Caenorhabditis elegans

(2011) E. M. H. Tank et al.   JOURNAL OF NEUROSCIENCE

Amyloid- /Fyn-Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease

(2011) E. D. Roberson et al.   JOURNAL OF NEUROSCIENCE

The Caenorhabditis elegans JIP3 Protein UNC-16 Functions As an Adaptor to Link Kinesin-1 with Cytoplasmic Dynein

(2011) M. Arimoto et al.   JOURNAL OF NEUROSCIENCE

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

UNC-33 (CRMP) and ankyrin organize microtubules and localize kinesin to polarize axon-dendrite sorting

(2011) Tapan A Maniar et al.   NATURE NEUROSCIENCE

The Many Faces of Tau

(2011) Meaghan Morris et al.   NEURON

OrthoList: A Compendium of C. elegans Genes with Human Orthologs

(2011) Daniel D. Shaye et al.   PLoS One

Genetic analysis of age-dependent defects of the Caenorhabditis elegans touch receptor neurons

(2011) C.-L. Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Action potentials drive body wall muscle contractions in Caenorhabditis elegans

(2011) S. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Targeting intrinsically disordered proteins in neurodegenerative and protein dysfunction diseases: another illustration of the D2concept

(2010) Vladimir N Uversky   Expert Review of Proteomics

Monitoring protein aggregation and toxicity in Alzheimer’s disease mouse models using in vivo imaging

(2010) Tara L. Spires-Jones et al.   METHODS

C. elegans multi-dendritic sensory neurons: Morphology and function

(2010) Adi Albeg et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

An Arf-like Small G Protein, ARL-8, Promotes the Axonal Transport of Presynaptic Cargoes by Suppressing Vesicle Aggregation

(2010) Matthew P. Klassen et al.   NEURON

The Caenorhabditis elegans Kinesin-3 Motor UNC-104/KIF1A Is Degraded upon Loss of Specific Binding to Cargo

(2010) Jitendra Kumar et al.   PLoS Genetics

Getting a Grip on Prions: Oligomers, Amyloids, and Pathological Membrane Interactions

(2009) Byron Caughey et al.   Annual Review of Biochemistry

SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans

(2009) Chris R. Guthrie et al.   HUMAN MOLECULAR GENETICS

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Aging Brain

(2008) Bruce A. Yankner et al.   Annual Review of Pathology-Mechanisms of Disease

Phosphorylation Regulates Tau Interactions with Src Homology 3 Domains of Phosphatidylinositol 3-Kinase, Phospholipase Cγ1, Grb2, and Src Family Kinases

(2008) C. Hugh Reynolds et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proline-directed Pseudo-phosphorylation at AT8 and PHF1 Epitopes Induces a Compaction of the Paperclip Folding of Tau and Generates a Pathological (MC-1) Conformation

(2008) Sadasivam Jeganathan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dendritic Spine Loss and Synaptic Alterations in Alzheimer’s Disease

(2008) Marlen Knobloch et al.   MOLECULAR NEUROBIOLOGY

Identification of an Axonal Kinesin-3 Motor for Fast Anterograde Vesicle Transport that Facilitates Retrograde Transport of Neuropeptides

(2007) Rosemarie V. Barkus et al.   MOLECULAR BIOLOGY OF THE CELL