Hypoimmune cells resist rejection in monkeys

Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression

(2023) Alessia Gravina et al.   NATURE BIOTECHNOLOGY

Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques

(2023) Xiaomeng Hu et al.   NATURE BIOTECHNOLOGY

The SIRPα–CD47 immune checkpoint in NK cells

(2021) Tobias Deuse et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients

(2019) Tobias Deuse et al.   NATURE BIOTECHNOLOGY

Endogenous glucocorticoids control host resistance to viral infection through the tissue-specific regulation of PD-1 expression on NK cells

(2018) Linda Quatrini et al.   NATURE IMMUNOLOGY

Human Leukocyte Antigen Class I and II Knockout Human Induced Pluripotent Stem Cell–Derived Cells: Universal Donor for Cell Therapy

(2018) Saidulu Mattapally et al.   Journal of the American Heart Association

HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells

(2017) Germán G Gornalusse et al.   NATURE BIOTECHNOLOGY

Heterelogous expression of mutated HLA-G decreases immunogenicity of human embryonic stem cells and their epidermal derivatives

(2014) Longmei Zhao et al.   Stem Cell Research

HLA Engineering of Human Pluripotent Stem Cells

(2013) Laura Riolobos et al.   MOLECULAR THERAPY