Systematic discovery of neoepitope–HLA pairs for neoantigens shared among patients and tumor types

The peptide woods are lovely, dark and deep: Hunting for novel cancer antigens

(2023) Daniel Oreper et al.   SEMINARS IN IMMUNOLOGY

Cancer vaccines as promising immuno-therapeutics: platforms and current progress

(2022) Jian Liu et al.   Journal of Hematology & Oncology

Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA

(2022) Smita S. Chandran et al.   NATURE MEDICINE

Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer

(2022) Rom Leidner et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bispecific antibodies targeting mutant RAS neoantigens

(2021) Jacqueline Douglass et al.   Science Immunology

High‐throughput identification of conditional MHCI ligands and scaled‐up production of conditional MHCI complexes

(2021) Martine Darwish et al.   PROTEIN SCIENCE

NEPdb: A Database of T-Cell Experimentally-Validated Neoantigens and Pan-Cancer Predicted Neoepitopes for Cancer Immunotherapy

(2021) Jiaqi Xia et al.   Frontiers in Immunology

Neoantigen: A New Breakthrough in Tumor Immunotherapy

(2021) Zheying Zhang et al.   Frontiers in Immunology

Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting

(2021) Adham S. Bear et al.   Nature Communications

caAtlas: An immunopeptidome atlas of human cancer

(2021) Xinpei Yi et al.   iScience

Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition

(2020) Lauren E. Stopfer et al.   Nature Communications

Extending the Comprehensiveness of Immunopeptidome Analyses Using Isobaric Peptide Labeling

(2020) Sibylle Pfammatter et al.   ANALYTICAL CHEMISTRY

Impact of Cysteine Residues on MHC Binding Predictions and Recognition by Tumor-Reactive T Cells

(2020) Abraham Sachs et al.   JOURNAL OF IMMUNOLOGY

A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer

(2020) Patrick A. Ott et al.   CELL

Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer

(2019) Winifred Lo et al.   Cancer Immunology Research

Next-generation HLA typing of 382 International Histocompatibility Working Group reference B-Lymphoblastoid cell lines: report from the 17th International HLA and Immunogenetics Workshop

(2019) Lisa E. Creary et al.   HUMAN IMMUNOLOGY

Direct Detection and Quantification of Neo-antigens

(2019) Qing Wang et al.   Cancer Immunology Research

Predicted MHC peptide binding promiscuity explains MHC class I ‘hotspots’ of antigen presentation defined by mass spectrometry eluted ligand data

(2018) Emma Christine Jappe et al.   IMMUNOLOGY

Acute Pharmacologic Degradation of a Stable Antigen Enhances Its Direct Presentation on MHC Class I Molecules

(2018) Sarah C. Moser et al.   Frontiers in Immunology

Assembling the Community-Scale Discoverable Human Proteome

(2018) Mingxun Wang et al.   Cell Systems

Specific MHC-I Peptides Are Induced Using PROTACs

(2018) Stephanie M. Jensen et al.   Frontiers in Immunology

Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction

(2017) Jennifer G. Abelin et al.   IMMUNITY

Shared cancer neoantigens: Making private matters public

(2017) Christopher A. Klebanoff et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NetMHCpan-4.0: Improved Peptide–MHC Class I Interaction Predictions Integrating Eluted Ligand and Peptide Binding Affinity Data

(2017) Vanessa Jurtz et al.   JOURNAL OF IMMUNOLOGY

Transcriptome-wide measurement of translation by ribosome profiling

(2017) Nicholas J. McGlincy et al.   METHODS

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

(2017) Ugur Sahin et al.   NATURE

Accelerating Discovery of Functional Mutant Alleles in Cancer

(2017) Matthew T. Chang et al.   Cancer Discovery

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

(2016) Eric Tran et al.   NEW ENGLAND JOURNAL OF MEDICINE

HLA class I-restricted MYD88 L265P-derived peptides as specific targets for lymphoma immunotherapy

(2016) Annika Nelde et al.   OncoImmunology

Transcriptome-wide measurement of ribosomal occupancy by ribosome profiling

(2015) Florian Aeschimann et al.   METHODS

Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes

(2015) Sachet A Shukla et al.   NATURE BIOTECHNOLOGY

Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes

(2015) Andrew D. Skora et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The first step of peptide selection in antigen presentation by MHC class I molecules

(2015) Malgorzata A. Garstka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-throughput pairing of T cell receptor α and β sequences

(2015) Bryan Howie et al.   Science Translational Medicine

Multiplex Identification of Antigen-Specific T Cell Receptors Using a Combination of Immune Assays and Immune Receptor Sequencing

(2015) Mark Klinger et al.   PLoS One