Development of a separation platform comprising magnetic beads combined with the CRISPR/Cas12a system enabling ultrasensitive and rapid detection of miRNA-21

Engineered G-Quadruplex-Embedded Self-Quenching Probes Regulate Single Probe-Based Multiplex Isothermal Amplification to Light Road Lamp Probes for Sensitized Determination of microRNAs

(2022) Jie Wang et al.   ANALYTICAL CHEMISTRY

Combining functional hairpin probes with disordered cleavage of CRISPR/Cas12a protease to screen for B lymphocytic leukemia

(2022) Hongbo Li et al.   BIOSENSORS & BIOELECTRONICS

A dual-functional magnetic microsphere for ICP-MS quantification and fluorescence imaging of matrix metalloproteinase 2 in cell secretion

(2021) Xiaoting Li et al.   ANALYTICA CHIMICA ACTA

“Dual-Signal-On” Integrated-Type Biosensor for Portable Detection of miRNA: Cas12a-Induced Photoelectrochemistry and Fluorescence Strategy

(2021) Haoran Shen et al.   ANALYTICAL CHEMISTRY

Universal and Naked-Eye Gene Detection Platform Based on the Clustered Regularly Interspaced Short Palindromic Repeats/Cas12a/13a System

(2020) Chaoqun Yuan et al.   ANALYTICAL CHEMISTRY

RNA Strand Displacement Responsive CRISPR/Cas9 System for mRNA Sensing

(2019) Yue Li et al.   ANALYTICAL CHEMISTRY

Signal Amplification in Living Cells: A Review of microRNA Detection and Imaging

(2019) Hanyong Peng et al.   ANALYTICAL CHEMISTRY

Ultra-sensitive label-free electrochemical detection of the acute leukaemia gene Pax-5a based on enzyme-assisted cycle amplification

(2019) Weihua Zhao et al.   BIOSENSORS & BIOELECTRONICS

Palindromic Molecule Beacon-Based Cascade Amplification for Colorimetric Detection of Cancer Genes

(2018) Zhi-Fa Shen et al.   ANALYTICAL CHEMISTRY

CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

(2018) Shi-Yuan Li et al.   CELL RESEARCH

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

(2018) Janice S. Chen et al.   SCIENCE

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

(2018) Jonathan S. Gootenberg et al.   SCIENCE

Cancer Diagnostics via Ultrasensitive Multiplexed Detection of Parathyroid Hormone-Related Peptides with a Microfluidic Immunoarray

(2016) Brunah A. Otieno et al.   ANALYTICAL CHEMISTRY

Surface Enhanced Laser Desorption Ionization of Phospholipids on Gold Nanoparticles for Mass Spectrometric Immunoassay

(2016) Xiang-Cheng Lin et al.   ANALYTICAL CHEMISTRY

Specific capture of the hydrolysate on magnetic beads for sensitive detecting plant vacuolar processing enzyme activity

(2016) Jun Zhou et al.   BIOSENSORS & BIOELECTRONICS

Dual-excitation upconverting nanoparticle and quantum dot aptasensor for multiplexed food pathogen detection

(2016) Hasan Kurt et al.   BIOSENSORS & BIOELECTRONICS

Sensitive DNA detection and SNP discrimination using ultrabright SERS nanorattles and magnetic beads for malaria diagnostics

(2016) Hoan T. Ngo et al.   BIOSENSORS & BIOELECTRONICS

An Efficient Particle-Based DNA Circuit System: Catalytic Disassembly of DNA/PEG-Modified Gold Nanoparticle-Magnetic Bead Composites for Colorimetric Detection of miRNA

(2016) Motoi Oishi et al.   Small

Scientists Probe MicroRNAs’ Role in Cancer

(2010) Tracy Hampton   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Altered MicroRNA Expression in Cervical Carcinomas

(2008) J.-W. Lee et al.   CLINICAL CANCER RESEARCH

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA

(2008) Luciano A. Marraffini et al.   SCIENCE