Selection pressure on human STR loci and its relevance in repeat expansion disease

Evolution and Development of the Mammalian Cerebral Cortex

(2017) Zoltán Molnár et al.   BRAIN BEHAVIOR AND EVOLUTION

Impaired DNA Damage Repair as a Common Feature of Neurodegenerative Diseases and Psychiatric Disorders

(2015) H. Shiwaku et al.   CURRENT MOLECULAR MEDICINE

Systematic Analysis of Fly Models with Multiple Drivers Reveals Different Effects of Ataxin-1 and Huntingtin in Neuron Subtype-Specific Expression

(2015) Risa Shiraishi et al.   PLoS One

RNA–protein interactions in unstable microsatellite diseases

(2014) Apoorva Mohan et al.   BRAIN RESEARCH

Expansion of the polyQ repeats in THAP11 forms intranuclear aggregation and causes cell G0/G1 arrest

(2014) Rong-Hua Yin et al.   CELL BIOLOGY INTERNATIONAL

Male eyespan size is associated with meiotic drive in wild stalk-eyed flies (Teleopsis dalmanni)

(2014) A J Cotton et al.   HEREDITY

Convergent transcription through microsatellite repeat tracts induces cell death

(2014) William Y. Lin et al.   MOLECULAR BIOLOGY REPORTS

When to use the Bonferroni correction

(2014) Richard A. Armstrong   OPHTHALMIC AND PHYSIOLOGICAL OPTICS

RNA-mediated pathogenic mechanisms in polyglutamine diseases and amyotrophic lateral sclerosis

(2014) Ho Yin Edwin Chan   Frontiers in Cellular Neuroscience

Mutations in the PQBP1 gene prevent its interaction with the spliceosomal protein U5–15kD

(2014) Mineyuki Mizuguchi et al.   Nature Communications

Roles of the nucleolus in the CAG RNA-mediated toxicity

(2013) Ho Tsoi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

PQBP1, a factor linked to intellectual disability, affects alternative splicing associated with neurite outgrowth

(2013) Q. Wang et al.   GENES & DEVELOPMENT

Cross-Species Analysis of Genic GC3 Content and DNA Methylation Patterns

(2013) Tatiana Tatarinova et al.   Genome Biology and Evolution

Crystal Structures and RNA-binding Properties of the RNA Recognition Motifs of Heterogeneous Nuclear Ribonucleoprotein L

(2013) Wenjuan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Interaction of Polyglutamine Peptides with Lipid Membranes Is Regulated by Flanking Sequences Associated with Huntingtin

(2013) Kathleen A. Burke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regional DNA methylation differences between humans and chimpanzees are associated with genetic changes, transcriptional divergence and disease genes

(2013) Kei Fukuda et al.   JOURNAL OF HUMAN GENETICS

RNA toxicity in polyglutamine disorders: concepts, models, and progress of research

(2013) Agnieszka Fiszer et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Activities at the Universal Protein Resource (UniProt)

(2013)   NUCLEIC ACIDS RESEARCH

Huntington's disease: underlying molecular mechanisms and emerging concepts

(2013) John Labbadia et al.   TRENDS IN BIOCHEMICAL SCIENCES

Solution Model of the Intrinsically Disordered Polyglutamine Tract-Binding Protein-1

(2012) Martin Rees et al.   BIOPHYSICAL JOURNAL

Dissecting the role of low-complexity regions in the evolution of vertebrate proteins

(2012) Núria Radó-Trilla et al.   BMC EVOLUTIONARY BIOLOGY

Spt4 Is Selectively Required for Transcription of Extended Trinucleotide Repeats

(2012) Chia-Rung Liu et al.   CELL

Distinct Mutational Behaviors Differentiate Short Tandem Repeats from Microsatellites in the Human Genome

(2012) Guruprasad Ananda et al.   Genome Biology and Evolution

Length of polyglutamine tract affects secondary and tertiary structures of huntingtin protein

(2012) Shivang N. Vachharajani et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Microsatellites as Targets of Natural Selection

(2012) R. J. Haasl et al.   MOLECULAR BIOLOGY AND EVOLUTION

An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin

(2012) Valentina Lo Sardo et al.   NATURE NEUROSCIENCE

Polyglutamine Repeats Are Associated to Specific Sequence Biases That Are Conserved among Eukaryotes

(2012) Matteo Ramazzotti et al.   PLoS One

Variation within the Huntington's Disease Gene Influences Normal Brain Structure

(2012) Mark Mühlau et al.   PLoS One

Nucleotide Excision Repair, Mismatch Repair, and R-Loops Modulate Convergent Transcription-Induced Cell Death and Repeat Instability

(2012) Yunfu Lin et al.   PLoS One

Unexpanded and intermediate CAG polymorphisms at the SCA2 locus (ATXN2) in the Cuban population: evidence about the origin of expanded SCA2 alleles

(2011) José Miguel Laffita-Mesa et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Overestimation of nonsynonymous/synonymous rate ratio by reverse-translation of aligned amino acid sequences

(2011) Yoshiyuki Suzuki   GENES & GENETIC SYSTEMS

Novel mechanism of Hsp70 chaperone-mediated prevention of polyglutamine aggregates in a cellular model of huntington disease

(2011) I. V. Guzhova et al.   HUMAN MOLECULAR GENETICS

Inhibiting the Nucleation of Amyloid Structure in a Huntingtin Fragment by Targeting α-Helix-Rich Oligomeric Intermediates

(2011) Rakesh Mishra et al.   JOURNAL OF MOLECULAR BIOLOGY

Proline repeats, in cis- and trans-positions, confer protection against the toxicity of misfolded proteins in a mammalian cellular model

(2011) Pratibha Siwach et al.   NEUROSCIENCE RESEARCH

DNA slip-outs cause RNA polymerase II arrest in vitro : potential implications for genetic instability

(2011) Viviana Salinas-Rios et al.   NUCLEIC ACIDS RESEARCH

Ensembl 2012

(2011) P. Flicek et al.   NUCLEIC ACIDS RESEARCH

New insights into repeat instability

(2011) Elizabeth I. McIvor et al.   RNA Biology

Variable Tandem Repeats Accelerate Evolution of Coding and Regulatory Sequences

(2010) Rita Gemayel et al.   Annual Review of Genetics

Length polymorphism and head shape association among genes with polyglutamine repeats in the stalk-eyed fly, Teleopsis dalmanni

(2010) Leanna M Birge et al.   BMC EVOLUTIONARY BIOLOGY

Natural selection drives the accumulation of amino acid tandem repeats in human proteins

(2010) L. Mularoni et al.   GENOME RESEARCH

Structural Diversity of Triplet Repeat RNAs

(2010) Krzysztof Sobczak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Convergent Transcription through a Long CAG Tract Destabilizes Repeats and Induces Apoptosis

(2010) Y. Lin et al.   MOLECULAR AND CELLULAR BIOLOGY

Elevated Evolutionary Rate in Genes with Homopolymeric Amino Acid Repeats Constituting Nondisordered Structure

(2010) J. Gojobori et al.   MOLECULAR BIOLOGY AND EVOLUTION

Trinucleotide repeats in human genome and exome

(2010) Piotr Kozlowski et al.   NUCLEIC ACIDS RESEARCH

Polyglutamine Diseases: Where does Toxicity Come from? What is Toxicity? Where are We Going?

(2010) T. Takahashi et al.   Journal of Molecular Cell Biology

Polyglutamine tract binding protein-1 is an intrinsically unstructured protein

(2009) Masaki Takahashi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Consensus features of microsatellite distribution: Microsatellite contents are universally correlated with recombination rates and are preferentially depressed by centromeres in multicellular eukaryotic genomes

(2009) Wen-Jiu Guo et al.   GENOMICS

Can GC Content at Third-Codon Positions Be Used as a Proxy for Isochore Composition?

(2009) E. Elhaik et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genomic Drift and Evolution of Microsatellite DNAs in Human Populations

(2009) N. Takezaki et al.   MOLECULAR BIOLOGY AND EVOLUTION

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Unstable Tandem Repeats in Promoters Confer Transcriptional Evolvability

(2009) M. D. Vinces et al.   SCIENCE

Comparative Genomics and Molecular Dynamics of DNA Repeats in Eukaryotes

(2008) G.-F. Richard et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

VarySysDB: a human genetic polymorphism database based on all H-InvDB transcripts

(2008) M. K. Shimada et al.   NUCLEIC ACIDS RESEARCH

Simple sequence repeats: genetic modulators of brain function and behavior

(2008) John W. Fondon et al.   TRENDS IN NEUROSCIENCES

Phylogenetic Comparison of Huntingtin Homologues Reveals the Appearance of a Primitive polyQ in Sea Urchin

(2007) M. Tartari et al.   MOLECULAR BIOLOGY AND EVOLUTION