Safety and immunogenicity of a novel multivalent OspA-based vaccine candidate against Lyme borreliosis: a randomised, phase 1 study in healthy adults

The year that shaped the outcome of the OspA vaccine for human Lyme disease

(2022) Raymond J. Dattwyler et al.   npj Vaccines

Epidemiology of Lyme Disease

(2022) Paul Mead   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Lyme disease in Western Europe: an emerging problem? A systematic review

(2019) Olivia Vandekerckhove et al.   ACTA CLINICA BELGICA

Infection Kinetics and Tropism of Borrelia burgdorferi sensu lato in Mouse After Natural (via Ticks) or Artificial (Needle) Infection Depends on the Bacterial Strain

(2018) Natacha Sertour et al.   Frontiers in Microbiology

Identification of a defined linear epitope in the OspA protein of the Lyme disease spirochetes that elicits bactericidal antibody responses: Implications for vaccine development

(2017) Jerilyn R. Izac et al.   VACCINE

The novel Lyme borreliosis vaccine VLA15 shows broad protection against Borrelia species expressing six different OspA serotypes

(2017) Pär Comstedt et al.   PLoS One

Identification of a novel pathogenic Borrelia species causing Lyme borreliosis with unusually high spirochaetaemia: a descriptive study

(2016) Bobbi S Pritt et al.   LANCET INFECTIOUS DISEASES

Time for a Different Approach to Lyme Disease and Long-Term Symptoms

(2016) Michael T. Melia et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lyme Carditis

(2015) Matthew L. Robinson et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Characterization and optimization of a novel vaccine for protection against Lyme borreliosis

(2015) Pär Comstedt et al.   VACCINE

A Novel Multivalent OspA Vaccine against Lyme Borreliosis Is Safe and Immunogenic in an Adult Population Previously Infected with Borrelia burgdorferi Sensu Lato

(2014) Nina Wressnigg et al.   Clinical and Vaccine Immunology

Safety and immunogenicity of a novel multivalent OspA vaccine against Lyme borreliosis in healthy adults: a double-blind, randomised, dose-escalation phase 1/2 trial

(2013) Nina Wressnigg et al.   LANCET INFECTIOUS DISEASES

Relationship between Immunity to Borrelia burgdorferi Outer-surface Protein A (OspA) and Lyme Arthritis

(2011) Allen C. Steere et al.   CLINICAL INFECTIOUS DISEASES