Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA

Plasmodium falciparum in Aotus nancymaae: A New Model for Placental Malaria

(2022) Ankur Sharma et al.   JOURNAL OF INFECTIOUS DISEASES

The Development, Fine Specificity, and Importance of High-Avidity Antibodies to VAR2CSA in Pregnant Cameroonian Women Living in Yaoundé, an Urban City

(2021) Koko Vanda et al.   Frontiers in Immunology

Progress and Insights Toward an Effective Placental Malaria Vaccine

(2021) Benoît Gamain et al.   Frontiers in Immunology

Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria

(2021) Elizabeth H Aitken et al.   eLife

PRIMVAC vaccine adjuvanted with Alhydrogel or GLA-SE to prevent placental malaria: a first-in-human, randomised, double-blind, placebo-controlled study

(2020) Sodiomon B Sirima et al.   LANCET INFECTIOUS DISEASES

First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC, a vaccine candidate to prevent pregnancy-associated malaria

(2019) Benjamin Mordmüller et al.   CLINICAL INFECTIOUS DISEASES

Preclinical immunogenicity and safety of the cGMP-grade placental malaria vaccine PRIMVAC

(2019) Arnaud Chêne et al.   EBioMedicine

Burden, pathology, and costs of malaria in pregnancy: new developments for an old problem

(2018) Stephen J Rogerson et al.   LANCET INFECTIOUS DISEASES

Antibody levels to recombinant VAR2CSA domains vary with Plasmodium falciparum parasitaemia, gestational age, and gravidity, but do not predict pregnancy outcomes

(2018) Michal Fried et al.   MALARIA JOURNAL

Antibody Profiling by Proteome Microarray with Multiplex Isotype Detection Reveals Overlap between Human and Aotus nancymaae Controlled Malaria Infections

(2018) Omid Taghavian et al.   PROTEOMICS

Down-selection of the VAR2CSA DBL1-2 expressed in E. coli as a lead antigen for placental malaria vaccine development

(2018) Arnaud Chêne et al.   npj Vaccines

Asymptomatic plasmodial infection in pregnant women: A global scenario

(2017) ElianaM Arango et al.   JOURNAL OF VECTOR BORNE DISEASES

Malaria in pregnancy: the relevance of animal models for vaccine development

(2017) Justin Doritchamou et al.   LAB ANIMAL

Protein-protein conjugate nanoparticles for malaria antigen delivery and enhanced immunogenicity

(2017) Puthupparampil V. Scaria et al.   PLoS One

VAR2CSA Domain-Specific Analysis of Naturally Acquired Functional Antibodies toPlasmodium falciparumPlacental Malaria

(2016) Justin Yai Alamou Doritchamou et al.   JOURNAL OF INFECTIOUS DISEASES

Bacterial superglue enables easy development of efficient virus-like particle based vaccines

(2016) Susan Thrane et al.   JOURNAL OF NANOBIOTECHNOLOGY

Safety and Immunogenicity of Pfs25-EPA/Alhydrogel®, a Transmission Blocking Vaccine against Plasmodium falciparum: An Open Label Study in Malaria Naïve Adults

(2016) Kawsar R. Talaat et al.   PLoS One

Parity-Dependent Recognition of DBL1X-3X Suggests an Important Role of the VAR2CSA High-Affinity CSA-Binding Region in the Development of the Humoral Response against Placental Malaria

(2015) Sébastien Dechavanne et al.   INFECTION AND IMMUNITY

Comparison of the specificity of antibodies to VAR2CSA in Cameroonian multigravidae with and without placental malaria: a retrospective case–control study

(2015) Anna Babakhanyan et al.   MALARIA JOURNAL

A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA

(2015) Susan Thrane et al.   PLoS One

Designing a VAR2CSA-based vaccine to prevent placental malaria

(2015) Michal Fried et al.   VACCINE

The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine

(2015) Morten A. Nielsen et al.   PLoS One

B-Cell Responses to Pregnancy-Restricted and -Unrestricted Plasmodium falciparum Erythrocyte Membrane Protein 1 Antigens in Ghanaian Women Naturally Exposed to Malaria Parasites

(2014) Paulina Ampomah et al.   INFECTION AND IMMUNITY

Identification of VAR2CSA Domain-Specific Inhibitory Antibodies of the Plasmodium falciparum Erythrocyte Membrane Protein 1 Using a Novel Flow Cytometry Assay

(2013) Harold Obiakor et al.   Clinical and Vaccine Immunology

Differential adhesion-inhibitory patterns of antibodies raised against two major variants of the NTS-DBL2X region of VAR2CSA

(2013) Justin Doritchamou et al.   VACCINE

Development of a Pfs25-EPA malaria transmission blocking vaccine as a chemically conjugated nanoparticle

(2013) Richard L. Shimp et al.   VACCINE

Multilaboratory Approach to Preclinical Evaluation of Vaccine Immunogens for Placental Malaria

(2012) Michal Fried et al.   INFECTION AND IMMUNITY

Structural and Functional Insight into How thePlasmodium falciparumVAR2CSA Protein Mediates Binding to Chondroitin Sulfate A in Placental Malaria

(2012) Thomas M. Clausen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New Insights into Acquisition, Boosting, and Longevity of Immunity to Malaria in Pregnant Women

(2012) Freya JI. Fowkes et al.   JOURNAL OF INFECTIOUS DISEASES

High Avidity Antibodies to Full-Length VAR2CSA Correlate with Absence of Placental Malaria

(2012) Yeung Lo Tutterrow et al.   PLoS One

The NTS-DBL2X Region of VAR2CSA Induces Cross-Reactive Antibodies That Inhibit Adhesion of Several Plasmodium falciparum Isolates to Chondroitin Sulfate A

(2011) Pascal Bigey et al.   JOURNAL OF INFECTIOUS DISEASES

Var2CSA Minimal CSA Binding Region Is Located within the N-Terminal Region

(2011) Anand Srivastava et al.   PLoS One

Antibodies That Induce Phagocytosis of Malaria Infected Erythrocytes: Effect of HIV Infection and Correlation with Clinical Outcomes

(2011) Ricardo Ataíde et al.   PLoS One

Differential Recognition of P. falciparum VAR2CSA Domains by Naturally Acquired Antibodies in Pregnant Women from a Malaria Endemic Area

(2010) Kim J. M. Brolin et al.   PLoS One

High efficacy of anti DBL4ɛ-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women

(2010) Pamela A. Magistrado et al.   VACCINE

Relationship between Human Immunodeficiency Virus Type 1 Coinfection, Anemia, and Levels and Function of Antibodies to Variant Surface Antigens in Pregnancy-Associated Malaria

(2009) A. Jaworowski et al.   Clinical and Vaccine Immunology

Development and characterization of a standardized ELISA including a reference serum on each plate to detect antibodies induced by experimental malaria vaccines

(2007) Kazutoyo Miura et al.   VACCINE