Mutation of epigenetic regulators TET2 and MLL3 in patients with HTLV-I-induced acute adult T-cell leukemia

Treatment and survival among 1594 patients with ATL

(2015) H. Katsuya et al.   BLOOD

Role of ASXL1 and TP53 mutations in the molecular classification and prognosis of acute myeloid leukemias with myelodysplasia-related changes

(2015) Raynier Devillier et al.   Oncotarget

Tumor Suppressor Inactivation in the Pathogenesis of Adult T-Cell Leukemia

(2015) Christophe Nicot   Journal of Oncology

MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia

(2014) Chong Chen et al.   CANCER CELL

Human T-cell Lymphotropic Virus Type I-Associated Adult T-cell Leukemia-Lymphoma: New Directions in Clinical Research

(2014) K. Tsukasaki et al.   CLINICAL CANCER RESEARCH

Human T-cell leukaemia virus type I and adult T-cell leukaemia-lymphoma

(2014) Kenji Ishitsuka et al.   LANCET ONCOLOGY

Tax impairs DNA replication forks and increases DNA breaks in specific oncogenic genome regions

(2014) Hassiba Chaib-Mezrag et al.   Molecular Cancer

Enhancer Malfunction in Cancer

(2014) Hans-Martin Herz et al.   MOLECULAR CELL

DNA Hydroxymethylation Profiling Reveals that WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia

(2014) Raajit Rampal et al.   Cell Reports

Exome sequencing identifies an MLL3 gene germ line mutation in a pedigree of colorectal cancer and acute myeloid leukemia

(2013) W.-D. Li et al.   BLOOD

Polycomb-Mediated Loss of miR-31 Activates NIK-Dependent NF-κB Pathway in Adult T Cell Leukemia and Other Cancers

(2012) Makoto Yamagishi et al.   CANCER CELL

Polycomb-group proteins in hematopoietic stem cell regulation and hematopoietic neoplasms

(2012) V Radulović et al.   LEUKEMIA

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

(2012) Panagiotis Ntziachristos et al.   NATURE MEDICINE

HTLV-I Tax Increases Genetic Instability by Inducing DNA Double Strand Breaks during DNA Replication and Switching Repair to NHEJ

(2012) Hicham H. Baydoun et al.   PLoS One

How I treat adult T-cell leukemia/lymphoma

(2011) A. Bazarbachi et al.   BLOOD

Overexpression of enhancer of zeste homolog 2 with trimethylation of lysine 27 on histone H3 in adult T-cell leukemia/lymphoma as a target for epigenetic therapy

(2011) D. Sasaki et al.   HAEMATOLOGICA

Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms

(2011) O Abdel-Wahab et al.   LEUKEMIA

Recurrent DNMT3A mutations in patients with myelodysplastic syndromes

(2011) M J Walter et al.   LEUKEMIA

Frequent Alteration of MLL3 Frameshift Mutations in Microsatellite Deficient Colorectal Cancer

(2011) Yoshiyuki Watanabe et al.   PLoS One

HTLV-I Tax-dependent and -independent events associated with immortalization of human primary T lymphocytes

(2010) M. Bellon et al.   BLOOD

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

(2010) Maria E. Figueroa et al.   CANCER CELL

Notch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1-associated adult T-cell leukemia

(2010) J. Pancewicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multi-Step Aberrant CpG Island Hyper-Methylation Is Associated with the Progression of Adult T–Cell Leukemia/Lymphoma

(2009) Hiaki Sato et al.   AMERICAN JOURNAL OF PATHOLOGY

CDKN1C (p57KIP2) Is a Direct Target of EZH2 and Suppressed by Multiple Epigenetic Mechanisms in Breast Cancer Cells

(2009) Xiaojing Yang et al.   PLoS One

A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4

(2009) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Central role of PI3K in transcriptional activation of hTERT in HTLV-I-infected cells

(2008) M. Bellon et al.   BLOOD

Definition, Prognostic Factors, Treatment, and Response Criteria of Adult T-Cell Leukemia-Lymphoma: A Proposal From an International Consensus Meeting

(2008) Kunihiro Tsukasaki et al.   JOURNAL OF CLINICAL ONCOLOGY