Article
Cardiac & Cardiovascular Systems
Magdy M. El-Sayed Ahmed, Sadia Z. Shah, Nan Zhang, Tambi Jarmi, Samuel Jacob, Ian A. Makey, Mathew Thomas, Basar Sareyyupoglu, Kevin P. Landolfo, David B. Erasmus, Si M. Pham
Summary: This study assessed the survival of lung transplant recipients from donors with abnormal kidney function and compared the lung recovery rates between donors with and without abnormal kidney function. The results showed that there was no significant difference in lung recipient survival. However, the lung recovery rate from donors with abnormal kidney function was lower compared to donors with normal kidney function.
ANNALS OF THORACIC SURGERY
(2023)
Article
Surgery
Elizabeth M. Sonnenberg, Jesse Y. Hsu, Jordana B. Cohen, Vishnu S. Potluri, Zhi Geng, Matthew H. Levine, Peter L. Abt, Peter P. Reese
Summary: This study found that kidney transplants from deceased donors with persistent acute kidney injury (AKI) did not have clinically meaningful differences in graft survival and function compared to transplants from donors without kidney injury.
Article
Medicine, Research & Experimental
Qiuhao Liu, Hedong Zhang, Mingda Zhong, Liang Tan, Shanbiao Hu, Longkai Peng, Xubiao Xie, Gongbin Lan
Summary: This study evaluated the safety and effectiveness of kidney transplantation from pediatric deceased donors with acute kidney injury (AKI). The results showed that pediatric AKI kidneys had better post-transplant outcomes compared to adult AKI kidneys. Therefore, this donor pool should be utilized to minimize waiting-list-related mortalities.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2023)
Article
Surgery
Caroline C. Jadlowiec, Wael A. Hanna, Jacob Ninan, Margaret S. Ryan, Devika M. Das, Maxwell Smith, Hasan Khamash, Amit K. Mathur, Andrew Singer, Adyr Moss, Kunam S. Reddy, Raymond L. Heilman
Summary: This study retrospectively assessed kidney transplant outcomes from high kidney donor profile index (KDPI >= 85%) donors with acute kidney injury (AKI). The findings showed that higher levels of AKI were associated with increased rates of delayed graft function and one-year death-censored graft failure.
CLINICAL TRANSPLANTATION
(2021)
Article
Urology & Nephrology
Conrado Lysandro Rodrigues Gomes, Thais Lyra Cleto-Yamane, Frederico Ruzani, Jose Hermogenes Rocco Suassuna
Summary: Although socioeconomic deprivation is associated with a higher incidence of acute kidney injury (AKI) and worse outcomes in high-income countries, the impact of these epidemiologic factors in developing countries is limited. This study analyzed pediatric and adult patients with dialysis-requiring AKI in private and public hospitals in Brazil and found no independent influence of hospital governance or socioeconomic factors on mortality. Baseline characteristics and disease severity primarily determined the prognosis of AKI.
KIDNEY INTERNATIONAL REPORTS
(2023)
Article
Gastroenterology & Hepatology
Kavish R. Patidar, Mobasshir A. Naved, Ananth Grama, Mohammad Adibuzzaman, Arzina Aziz Ali, James E. Slaven, Archita P. Desai, Marwan S. Ghabril, Lauren Nephew, Naga Chalasani, Eric S. Orman
Summary: This study investigated hospitalized patients with cirrhosis and acute kidney injury in the US and found that acute kidney disease developed in 1 in 3 patients, which was associated with worse survival and chronic kidney disease.
JOURNAL OF HEPATOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Marta Glowacka, Sara Lipka, Ewelina Mlynarska, Beata Franczyk, Jacek Rysz
Summary: COVID-19, primarily known as a respiratory illness, can also target the kidneys through the ACE2 receptor, leading to acute kidney injury. The development of AKI in COVID-19 patients is strongly associated with higher mortality, not only due to direct invasion of renal cells by the virus, but also involving mechanisms like hypovolemia and cytokine storm.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Critical Care Medicine
Rashid Alobaidi, Natalie Anton, Shauna Burkholder, Daniel Garros, Gonzalo Garcia Guerra, Emma H. Ulrich, Sean M. Bagshaw
Summary: In critically ill children, both persistent and transient acute kidney injury have different clinical characteristics and associations with outcomes. Acute kidney injury, even when short in duration, is significantly associated with worse outcomes and this risk increases with longer persistence independent of severity.
PEDIATRIC CRITICAL CARE MEDICINE
(2021)
Article
Health Care Sciences & Services
Charat Thongprayoon, Supawit Tangpanithandee, Caroline C. Jadlowiec, Shennen A. Mao, Michael A. Mao, Pradeep Vaitla, Prakrati C. Acharya, Napat Leeaphorn, Wisit Kaewput, Pattharawin Pattharanitima, Supawadee Suppadungsuk, Pajaree Krisanapan, Pitchaphon Nissaisorakarn, Matthew Cooper, Iasmina M. Craici, Wisit Cheungpasitporn
Summary: An unsupervised machine learning approach was used to cluster kidney transplant recipients with prolonged dialysis duration and identify three clinically distinct types. Despite dialysis duration exceeding 10 years, most recipients had good post-transplant outcomes, including those with moderate sensitization.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Health Care Sciences & Services
You-Lin Tain, Chien-Liang Liu, Hsiao-Ching Kuo, Chien-Ning Hsu
Summary: This study aimed to categorize AKI recovery patterns within 6 months after index hospital discharge and associate them with kidney outcomes. The results showed that AKI patients with persistent non-recovery and non-recovery were associated with a higher risk of adverse kidney outcomes. Risk stratification and kidney function monitoring plan at discharge are needed to improve post-AKI care.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Review
Medicine, General & Internal
Hanna Cholerzynska, Wiktoria Zasada, Hanna Michalak, Milosz Miedziaszczyk, Andrzej Oko, Ilona Idasiak-Piechocka
Summary: Acute kidney injury (AKI) and sudden exacerbation of chronic kidney disease (CKD) often require urgent kidney replacement therapy (UKRT). Peritoneal dialysis (PD) is seen as a viable option for managing these patients. This review examines recent literature on the clinical outcomes of urgent-start peritoneal dialysis (USPD) in CKD and AKI.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Sana Farooq Khan
Summary: This review discusses the current status and feasibility of peritoneal dialysis for the treatment of acute kidney injury, and calls for more standardized reporting of trial design, techniques, complications, and outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Emaad M. Abdel-Rahman, Ernst Casimir, Genevieve R. Lyons, Jennie Z. Ma, Jitendra K. Gautam
Summary: Identifying modifiable predictors of outcomes for acute kidney injury requiring hemodialysis is important for better care of patients. This study found that dialysis-related factors, such as frequency of intradialytic hypotension and net ultrafiltration, are associated with the outcomes of recovery, end stage kidney disease, or death. Optimizing dialysis prescription and close monitoring of outpatient dialysis are crucial in improving outcomes for these patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Pai-Chin Hsu, Chih-Han Liu, Wen-Chin Lee, Chien-Hsing Wu, Chien-Te Lee, Chien-Hao Su, Yu-Chin Lily Wang, Kai-Fan Tsai, Terry Ting-Yu Chiou
Summary: This study found that the use of offending drugs, AKI severity, and early dialysis requirement were independent predictors of AKD severity. Higher AKD severity was associated with negative outcomes in post-AKI patients.
Article
Cardiac & Cardiovascular Systems
Jia-Jin Chen, Chih-Hsiang Chang, Victor Chien-Chia Wu, Shang-Hung Chang, Kuo-Chun Hung, Pao-Hsien Chu, Shao-Wei Chen
Summary: This study investigated the occurrence and impact of D-AKI in different types of cardiac surgeries. The results showed that patients undergoing aortic surgery had a higher risk of D-AKI, but better renal recovery and lower long-term dialysis rates.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)