Histidine switch controlling pH-dependent protein folding and DNA binding in a transcription factor at the core of synthetic network devices

Uric acid as a modulator of glucose and lipid metabolism

(2015) William Gustavo Lima et al.   BIOCHIMIE

De novo protein design: how do we expand into the universe of possible protein structures?

(2015) Derek N Woolfson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Ligand-Binding Pocket Bridges DNA-Binding and Dimerization Domains of the Urate-Responsive MarR Homologue MftR from Burkholderia thailandensis

(2014) Ashish Gupta et al.   BIOCHEMISTRY

Synthetic therapeutic gene circuits in mammalian cells

(2014) Haifeng Ye et al.   FEBS LETTERS

Tumor Lysis Syndrome: New Challenges and Recent Advances

(2013) F. Perry Wilson et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

MarR family transcription factors

(2013) Anne Grove   CURRENT BIOLOGY

A biohybrid hydrogel for the urate-responsive release of urate oxidase

(2013) Christian Geraths et al.   JOURNAL OF CONTROLLED RELEASE

Depth: a web server to compute depth, cavity sizes, detect potential small-molecule ligand-binding cavities and predict the pKa of ionizable residues in proteins

(2013) Kuan Pern Tan et al.   NUCLEIC ACIDS RESEARCH

Study of PcaV from Streptomyces coelicolor yields new insights into ligand-responsive MarR family transcription factors

(2013) Jennifer R. Davis et al.   NUCLEIC ACIDS RESEARCH

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Tumor Lysis Syndrome

(2011) Scott C. Howard et al.   NEW ENGLAND JOURNAL OF MEDICINE

Synthetic Biology: Integrated Gene Circuits

(2011) N. Nandagopal et al.   SCIENCE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Attractive Interactions between Side Chains of Histidine-Histidine and Histidine-Arginine-Based Cationic Dipeptides in Water

(2010) Jan Heyda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Self-sufficient control of urate homeostasis in mice by a synthetic circuit

(2010) Christian Kemmer et al.   NATURE BIOTECHNOLOGY

Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis

(2010) Y.-M. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Critical biophysical properties in the Pseudomonas aeruginosa efflux gene regulator MexR are targeted by mutations conferring multidrug resistance

(2010) Cecilia Andrésen et al.   PROTEIN SCIENCE

Molecular Mechanisms of Ligand-Mediated Attenuation of DNA Binding by MarR Family Transcriptional Regulators

(2010) I. C. Perera et al.   Journal of Molecular Cell Biology

Mechanism for Attenuation of DNA Binding by MarR Family Transcriptional Regulators by Small Molecule Ligands

(2009) Inoka C. Perera et al.   JOURNAL OF MOLECULAR BIOLOGY

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

A Quantitative Model of Thermal Stabilization and Destabilization of Proteins by Ligands

(2008) Piotras Cimmperman et al.   BIOPHYSICAL JOURNAL

Protein secondary structure analyses from circular dichroism spectroscopy: Methods and reference databases

(2007) Lee Whitmore et al.   BIOPOLYMERS