Structure-based virtual screening and experimental validation of the discovery of inhibitors targeted towards the human coronavirus nucleocapsid protein

Middle East respiratory syndrome

(2015) Alimuddin Zumla et al.   LANCET

Crystallographic analysis of the N-terminal domain ofMiddle East respiratory syndrome coronavirusnucleocapsid protein

(2015) Yong-Sheng Wang et al.   Acta Crystallographica Section F-Structural Biology Communications

The SARS coronavirus nucleocapsid protein – Forms and functions

(2014) Chung-ke Chang et al.   ANTIVIRAL RESEARCH

Structural Basis for the Identification of the N-Terminal Domain of Coronavirus Nucleocapsid Protein as an Antiviral Target

(2014) Shing-Yen Lin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Coronaviruses: Important Emerging Human Pathogens

(2014) C. M. Coleman et al.   JOURNAL OF VIROLOGY

Human Coronaviruses Associated with Upper Respiratory Tract Infections in Three Rural Areas of Ghana

(2014) Michael Owusu et al.   PLoS One

Current progress in antiviral strategies

(2014) Zhiyong Lou et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The emergence of the Middle East Respiratory Syndrome coronavirus

(2014) Shauna Milne-Price et al.   Pathogens and Disease

Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein

(2013) I.-Jung Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Influenza virus nucleoprotein: structure, RNA binding, oligomerization and antiviral drug target

(2013) Sylvie Chenavas et al.   Future Microbiology

The structural basis of actinomycin D–binding induces nucleotide flipping out, a sharp bend and a left-handed twist in CGG triplet repeats

(2013) Yu-Sheng Lo et al.   NUCLEIC ACIDS RESEARCH

Development of an Anti-Influenza Drug Screening Assay Targeting Nucleoproteins with Tryptophan Fluorescence Quenching

(2012) Hui-Chen Hung et al.   ANALYTICAL CHEMISTRY

Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2012)

(2012) M. J. Adams et al.   ARCHIVES OF VIROLOGY

Oligomerization of the carboxyl terminal domain of the human coronavirus 229E nucleocapsid protein

(2012) Yu-Sheng Lo et al.   FEBS LETTERS

Contribution of common and recently described respiratory viruses to annual hospitalizations in children in South Africa

(2011) Marietjie Venter et al.   JOURNAL OF MEDICAL VIROLOGY

Acute lower respiratory infection in the developing world

(2011) Bradford D Gessner   Expert Review of Respiratory Medicine

Structures of the N- and C-terminal domains of MHV-A59 nucleocapsid protein corroborate a conserved RNA-protein binding mechanism in coronavirus

(2010) Yanlin Ma et al.   Protein & Cell

Coronavirus N Protein N-Terminal Domain (NTD) Specifically Binds the Transcriptional Regulatory Sequence (TRS) and Melts TRS-cTRS RNA Duplexes

(2009) Nicholas E. Grossoehme et al.   JOURNAL OF MOLECULAR BIOLOGY

Elucidation of the stability and functional regions of the human coronavirus OC43 nucleocapsid protein

(2009) Chun-Yu Huang et al.   PROTEIN SCIENCE

Human coronavirus NL63 infections in infants hospitalised with acute respiratory tract infections in South Africa

(2008) Heidi Smuts   Influenza and Other Respiratory Viruses

Role of human metapneumovirus, human coronavirus NL63 and human bocavirus in infants and young children with acute wheezing

(2008) Heidi Smuts et al.   JOURNAL OF MEDICAL VIROLOGY

Multiple Nucleic Acid Binding Sites and Intrinsic Disorder of Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein: Implications for Ribonucleocapsid Protein Packaging

(2008) C.-K. Chang et al.   JOURNAL OF VIROLOGY