炭素-窒素不斉軸を有するアトロプ異性キナゾリノンの化学

Asymmetric Synthesis of Axially Chiral C–N Atropisomers

(2022) Patricia Rodríguez-Salamanca et al.   CHEMISTRY-A EUROPEAN JOURNAL

Atroposelective Desymmetrization of Resorcinol-Bearing Quinazolinones via Cu-Catalyzed C–O Bond Formation

(2022) Hyung Yoon et al.   ORGANIC LETTERS

Catalytic Enantioselective Synthesis of C–N Atropisomeric Heterobiaryls

(2022) Peter C. Knipe et al.   SYNTHESIS-STUTTGART

Intermolecular Halogen Bond Detected in Racemic and Optically Pure N-C Axially Chiral 3-(2-Halophenyl)quinazoline-4-thione Derivatives

(2022) Ryosuke Matsui et al.   MOLECULES

Atropisomers beyond the C–C axial chirality: Advances in catalytic asymmetric synthesis

(2022) Guang-Jian Mei et al.   Chem

Asymmetric Synthesis of Isotopic Atropisomers based on ortho-CH3/CD3 Discrimination and Their Structural Properties

(2022) Shota Miwa et al.   JOURNAL OF ORGANIC CHEMISTRY

Directed Evolution of Flavin-Dependent Halogenases for Site- and Atroposelective Halogenation of 3-Aryl-4(3H)-Quinazolinones via Kinetic or Dynamic Kinetic Resolution

(2022) Harrison M. Snodgrass et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of Non-Biaryl Atropisomeric Amide Scaffolds Bearing a C–N Axis via Enantioselective Catalysis

(2022) Xiao Xiao et al.   MOLECULES

Chiral Pd-Catalyzed Enantioselective Syntheses of Various N–C Axially Chiral Compounds and Their Synthetic Applications

(2021) Osamu Kitagawa   ACCOUNTS OF CHEMICAL RESEARCH

Palladium-Catalyzed Atroposelective Coupling–Cyclization of 2-Isocyanobenzamides to Construct Axially Chiral 2-Aryl- and 2,3-Diarylquinazolinones

(2021) Fan Teng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Detection of Isotopic Atropisomerism Based on ortho-H/D Discrimination

(2021) Kazuya Saito et al.   ORGANIC LETTERS

Enantioselective aromatic amination?

(2020) Vinzenz Thönnißen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Thionation of Optically Pure N-C Axially Chiral Quinazolin-4-one Derivatives with Lawesson’s Reagent

(2020) Erina Niijima et al.   JOURNAL OF ORGANIC CHEMISTRY

Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3H)-ones and in vivo Studies on a Surgically Induced Rat Model of Osteoarthritis

(2019) Masakazu Atobe et al.   JOURNAL OF MEDICINAL CHEMISTRY

N–C Axially Chiral Compounds with an ortho-Fluoro Substituent and Steric Discrimination between Hydrogen and Fluorine Atoms Based on a Diastereoselective Model Reaction

(2019) Asumi Iida et al.   JOURNAL OF ORGANIC CHEMISTRY

N−C Axially Chiral Anilines: Electronic Effect on Barrier to Rotation and A Remote Proton Brake

(2018) Yumiko Iwasaki et al.   CHEMISTRY-A EUROPEAN JOURNAL

α-Alkylation of N–C Axially Chiral Quinazolinone Derivatives Bearing Various ortho-Substituted Phenyl Groups: Relation between Diastereoselectivity and the ortho-Substituent

(2018) Osamu Kitagawa et al.   SYNLETT

Diastereoselective α-Alkylation of Metallo Enamines Generated from N–C Axially Chiral Mebroqualone Derivatives

(2017) Mizuki Matsuoka et al.   ORGANIC LETTERS

Halogen Bonding in Organic Synthesis and Organocatalysis

(2016) David Bulfield et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of axially chiral biaryl compounds by asymmetric catalytic reactions with transition metals

(2016) Pauline Loxq et al.   COORDINATION CHEMISTRY REVIEWS

Catalytic Enantioselective Synthesis of N–C Axially Chiral Mebroqualone and Its Derivatives through Reductive Asymmetric Desymmetrization

(2016) Motohiro Hirai et al.   ORGANIC LETTERS

The synthesis of optically active N–C axially chiral tetrahydroquinoline and its response to an acid-accelerated molecular rotor

(2015) Yuya Suzuki et al.   CHEMICAL COMMUNICATIONS

Halogen Bonding in Supramolecular Chemistry

(2015) Lydia C. Gilday et al.   CHEMICAL REVIEWS

Enantioselective Synthesis of 3-Arylquinazolin-4(3H)-ones via Peptide-Catalyzed Atroposelective Bromination

(2015) Matthew E. Diener et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-disproportionation of enantiomers via achiral chromatography: a warning and an extra dimension in optical purifications

(2012) Vadim A. Soloshonok et al.   CHEMICAL SOCIETY REVIEWS

Proton Grease: An Acid Accelerated Molecular Rotor

(2012) Brent E. Dial et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Halogen bonding in halocarbon–protein complexes: a structural survey

(2011) Emilio Parisini et al.   CHEMICAL SOCIETY REVIEWS

Catalytic Enantioselective Synthesis of Novel Atropisomeric Compounds having an N-C Chiral Axis and Their Application to Asymmetric Reaction

(2011) Masashi Takahashi et al.   JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN

Synthesis of Enantioenriched N-Aryl-2-pyridones with Chiral C-N Axes by Rhodium-Catalyzed [2+2+2] Cycloaddition of Alkynes with Isocyanates

(2008) Ken Tanaka et al.   SYNLETT

Catalytic enantioselective synthesis of key intermediates for NET inhibitors using atropisomeric lactam chemistry

(2007) Osamu Kitagawa et al.   TETRAHEDRON LETTERS