Biomechanics of vascular mechanosensation and remodeling

Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex

(2015) Brian G. Coon et al.   JOURNAL OF CELL BIOLOGY

Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point

(2015) Nicolas Baeyens et al.   eLife

Change of Direction in the Biomechanics of Atherosclerosis

(2014) Yumnah Mohamied et al.   ANNALS OF BIOMEDICAL ENGINEERING

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling

(2014) Nicolas Baeyens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial Cell Sensing of Flow Direction

(2013) Chong Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial RAF1/ERK activation regulates arterial morphogenesis

(2013) Y. Deng et al.   BLOOD

Left Ventricular Assist Devices and Gastrointestinal Bleeding: A Narrative Review of Case Reports and Case Series

(2013) Sameer Islam et al.   CLINICAL CARDIOLOGY

Fluid Shear Stress on Endothelial Cells Modulates Mechanical Tension across VE-Cadherin and PECAM-1

(2013) Daniel E. Conway et al.   CURRENT BIOLOGY

Computation in the rabbit aorta of a new metric – the transverse wall shear stress – to quantify the multidirectional character of disturbed blood flow

(2013) Véronique Peiffer et al.   JOURNAL OF BIOMECHANICS

Human haemodynamic frequency harmonics regulate the inflammatory phenotype of vascular endothelial cells

(2013) Ryan E. Feaver et al.   Nature Communications

Gating the mechanical channel Piezo1

(2012) Philip A. Gottlieb et al.   Channels

Localized Tensional Forces on PECAM-1 Elicit a Global Mechanotransduction Response via the Integrin-RhoA Pathway

(2012) Caitlin Collins et al.   CURRENT BIOLOGY

Experimental study of aortic flow in the ascending aorta via Particle Tracking Velocimetry

(2012) Utku Gülan et al.   EXPERIMENTS IN FLUIDS

A novel in vitro flow system for changing flow direction on endothelial cells

(2012) Chong Wang et al.   JOURNAL OF BIOMECHANICS

Activation of endothelial TRPV4 channels mediates flow-induced dilation in human coronary arterioles: role of Ca2+ entry and mitochondrial ROS signaling

(2011) Aaron H. Bubolz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Vascular Effects of Exercise: Endothelial Adaptations Beyond Active Muscle Beds

(2011) Jaume Padilla et al.   PHYSIOLOGY

Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces

(2010) Ramaswamy Krishnan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Platelet-Endothelial Cell Adhesion Molecule-1 Regulates Endothelial NO Synthase Activity and Localization Through Signal Transducers and Activators of Transcription 3–Dependent NOSTRIN Expression

(2010) Margaret E. McCormick et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of PECAM-1 in Arteriogenesis and Specification of Preexisting Collaterals

(2010) Zhongming Chen et al.   CIRCULATION RESEARCH

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress

(2009) Suelhem A. Mendoza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

PECAM-1 Is Necessary for Flow-Induced Vascular Remodeling

(2009) Zhongming Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mechanotransduction in an extracted cell model: Fyn drives stretch- and flow-elicited PECAM-1 phosphorylation

(2008) Yi-Jen Chiu et al.   JOURNAL OF CELL BIOLOGY

Mechanotransduction in vascular physiology and atherogenesis

(2008) Cornelia Hahn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY