Control of genetic stability by a new heterochromatin compaction pathway involving the Tip60 histone acetyltransferase

Acetylation of Histone H2AX at Lys 5 by the TIP60 Histone Acetyltransferase Complex Is Essential for the Dynamic Binding of NBS1 to Damaged Chromatin

(2015) Masae Ikura et al.   MOLECULAR AND CELLULAR BIOLOGY

The histone variant composition of centromeres is controlled by the pericentric heterochromatin state during the cell cycle

(2014) Ekaterina Boyarchuk et al.   JOURNAL OF CELL SCIENCE

Suv39h-Dependent H3K9me3 Marks Intact Retrotransposons and Silences LINE Elements in Mouse Embryonic Stem Cells

(2014) Aydan Bulut-Karslioglu et al.   MOLECULAR CELL

CDK2-dependent phosphorylation of Suv39H1 is involved in control of heterochromatin replication during cell cycle progression

(2014) Su Hyung Park et al.   NUCLEIC ACIDS RESEARCH

DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin

(2014) M. K. Ayrapetov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct roles for Sir2 and RNAi in centromeric heterochromatin nucleation, spreading and maintenance

(2013) Alessia Buscaino et al.   EMBO JOURNAL

Prolyl isomerase Pin1 negatively regulates the stability of SUV39H1 to promote tumorigenesis in breast cancer

(2013) Prem Khanal et al.   FASEB JOURNAL

Interplay between chromatin-modifying enzymes controls colon cancer progression through Wnt signaling

(2013) Martine Chevillard-Briet et al.   HUMAN MOLECULAR GENETICS

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy

(2013) Jan R. Dörr et al.   NATURE

The Histone Methyltransferase SUV39H1 Suppresses Embryonal Rhabdomyosarcoma Formation in Zebrafish

(2013) Colleen E. Albacker et al.   PLoS One

Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability

(2013) D. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bromodomain Protein Brd4 Associated with Acetylated Chromatin Is Important for Maintenance of Higher-order Chromatin Structure

(2012) Ranran Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The chromatin remodeler p400 ATPase facilitates Rad51-mediated repair of DNA double-strand breaks

(2012) Céline Courilleau et al.   JOURNAL OF CELL BIOLOGY

Deacetylation of H4-K16Ac and heterochromatin assembly in senescence

(2012) Kévin Contrepois et al.   Epigenetics & Chromatin

SUMOylation promotes de novo targeting of HP1α to pericentric heterochromatin

(2011) Christèle Maison et al.   NATURE GENETICS

Cancer-associated alteration of pericentromeric heterochromatin may contribute to chromosome instability

(2011) R B Slee et al.   ONCOGENE

Parallel pathways in RAF-induced senescence and conditions for its reversion

(2011) M Jeanblanc et al.   ONCOGENE

Aberrant Overexpression of Satellite Repeats in Pancreatic and Other Epithelial Cancers

(2011) D. T. Ting et al.   SCIENCE

Histone H4 Lysine 12 Acetylation Regulates Telomeric Heterochromatin Plasticity in Saccharomyces cerevisiae

(2011) Bo O. Zhou et al.   PLoS Genetics

Physical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex

(2010) Catherine Chailleux et al.   BIOCHEMICAL JOURNAL

Structural implications for K5/K12-di-acetylated histone H4 recognition by the second bromodomain of BRD2

(2010) Takashi Umehara et al.   FEBS LETTERS

A chromodomain switch mediated by histone H3 Lys 4 acetylation regulates heterochromatin assembly

(2010) B. Xhemalce et al.   GENES & DEVELOPMENT

NuA4-dependent Acetylation of Nucleosomal Histones H4 and H2A Directly Stimulates Incorporation of H2A.Z by the SWR1 Complex

(2010) Mohammed Altaf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair

(2010) Ye Xu et al.   JOURNAL OF CELL BIOLOGY

DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions

(2009) Suhasni Gopalakrishnan et al.   HUMAN MOLECULAR GENETICS

The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways

(2009) L Mattera et al.   ONCOGENE

Linking Heterochromatin Protein 1 (HP1) to cancer progression

(2008) George K. Dialynas et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS