Formin-mediated actin polymerization at cell–cell junctions stabilizes E-cadherin and maintains monolayer integrity during wound repair

Actin-Delimited Adhesion-Independent Clustering of E-Cadherin Forms the Nanoscale Building Blocks of Adherens Junctions

(2015) Yao Wu et al.   DEVELOPMENTAL CELL

Cdc42 Mediates Bmp-Induced Sprouting Angiogenesis through Fmnl3-Driven Assembly of Endothelial Filopodia in Zebrafish

(2015) Yuki Wakayama et al.   DEVELOPMENTAL CELL

Formin-Mediated Actin Polymerization at Endothelial Junctions Is Required for Vessel Lumen Formation and Stabilization

(2015) Li-Kun Phng et al.   DEVELOPMENTAL CELL

Profilin-1 Serves as a Gatekeeper for Actin Assembly by Arp2/3-Dependent and -Independent Pathways

(2015) Jeremy D. Rotty et al.   DEVELOPMENTAL CELL

Profilin Regulates F-Actin Network Homeostasis by Favoring Formin over Arp2/3 Complex

(2015) Cristian Suarez et al.   DEVELOPMENTAL CELL

Junctional actin assembly is mediated by Formin-like 2 downstream of Rac1

(2015) Katharina Grikscheit et al.   JOURNAL OF CELL BIOLOGY

The formin FMNL3 assembles plasma membrane protrusions that participate in cell–cell adhesion

(2015) Timothy J. Gauvin et al.   MOLECULAR BIOLOGY OF THE CELL

SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton

(2015) Tadamoto Isogai et al.   Scientific Reports

Homeostatic Actin Cytoskeleton Networks Are Regulated by Assembly Factor Competition for Monomers

(2014) Thomas A. Burke et al.   CURRENT BIOLOGY

Cortical F-actin stabilization generates apical–lateral patterns of junctional contractility that integrate cells into epithelia

(2014) Selwin K. Wu et al.   NATURE CELL BIOLOGY

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

(2014) Z. Guo et al.   Science Signaling

An optogenetic tool for the activation of endogenous diaphanous-related formins induces thickening of stress fibers without an increase in contractility

(2013) Megha Vaman Rao et al.   Cytoskeleton

Guidance of collective cell migration by substrate geometry

(2013) Kevin Doxzen et al.   Integrative Biology

Binding to F-actin guides cadherin cluster assembly, stability, and movement

(2013) Soonjin Hong et al.   JOURNAL OF CELL BIOLOGY

Biotin ligase tagging identifies proteins proximal to E-cadherin, including lipoma preferred partner, a regulator of epithelial cell–cell and cell–substrate adhesion

(2013) Christina M. Van Itallie et al.   JOURNAL OF CELL SCIENCE

Cadherin adhesome at a glance

(2013) R. Zaidel-Bar   JOURNAL OF CELL SCIENCE

F- and G-actin homeostasis regulates mechanosensitive actin nucleation by formins

(2013) Chiharu Higashida et al.   NATURE CELL BIOLOGY

An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)

(2013) R Y-J Huang et al.   Cell Death & Disease

Formin mDia1 senses and generates mechanical forces on actin filaments

(2013) Antoine Jégou et al.   Nature Communications

A WAVE2–Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens

(2012) Suzie Verma et al.   MOLECULAR BIOLOGY OF THE CELL

Aurora B Regulates Formin mDia3 in Achieving Metaphase Chromosome Alignment

(2011) Lina Cheng et al.   DEVELOPMENTAL CELL

Cyclic stretch induces reorientation of cells in a Src family kinase- and p130Cas-dependent manner

(2011) Verena Niediek et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway

(2011) Eva M. Kovacs et al.   NATURE CELL BIOLOGY

Collective cell guidance by cooperative intercellular forces

(2011) Dhananjay T. Tambe et al.   NATURE MATERIALS

Deficiency of mDia, an Actin Nucleator, Disrupts Integrity of Neuroepithelium and Causes Periventricular Dysplasia

(2011) Dean Thumkeo et al.   PLoS One

The Extracellular Architecture of Adherens Junctions Revealed by Crystal Structures of Type I Cadherins

(2011) Oliver J. Harrison et al.   STRUCTURE

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

Adherens junctions: from molecules to morphogenesis

(2010) Tony J. C. Harris et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epithelial–Mesenchymal Transition: From Molecular Mechanisms, Redox Regulation to Implications in Human Health and Disease

(2009) Stefania Cannito et al.   ANTIOXIDANTS & REDOX SIGNALING

Identification and Characterization of a Small Molecule Inhibitor of Formin-Mediated Actin Assembly

(2009) Syed A. Rizvi et al.   CHEMISTRY & BIOLOGY

Cortactin Is a Functional Target of E-cadherin-activated Src Family Kinases in MCF7 Epithelial Monolayers

(2009) Gang Ren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Cell-Cell Adhesion by Abi/Diaphanous Complexes

(2009) J. R. Ryu et al.   MOLECULAR AND CELLULAR BIOLOGY

Unleashing formins to remodel the actin and microtubule cytoskeletons

(2009) Melissa A. Chesarone et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The cell-cell adhesion molecule E-cadherin

(2008) F. van Roy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Diaphanous regulates myosin and adherens junctions to control cell contractility and protrusive behavior during morphogenesis

(2008) C. C. F. Homem et al.   DEVELOPMENT

The mammalian formin FHOD1 is activated through phosphorylation by ROCK and mediates thrombin-induced stress fibre formation in endothelial cells

(2008) Ryu Takeya et al.   EMBO JOURNAL

Role of Src-family kinases in formation of the cortical actin cap at the dorsal cell surface

(2008) Takahisa Kuga et al.   EXPERIMENTAL CELL RESEARCH