Population pharmacokinetics and pharmacodynamics of efmarodocokin alfa (IL-22Fc)

Identification of an IL-22-Dependent Gene Signature as a Pharmacodynamic Biomarker

(2021) Julie Rae et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Challenges with development of a pharmacokinetics assay to measure a variably glycosylated fusion protein

(2021) Gizette Sperinde et al.   Bioanalysis

Pathophysiology of Inflammatory Bowel Diseases

(2020) John T. Chang   NEW ENGLAND JOURNAL OF MEDICINE

Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases

(2018) Eric G. Stefanich et al.   BIOCHEMICAL PHARMACOLOGY

Randomized phase 1 healthy volunteer study of UTTR1147A (IL-22Fc), a potential therapy for epithelial injury

(2018) Michael E Rothenberg et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Enteric Delivery of Regenerating Family Member 3 alpha Alters the Intestinal Microbiota and Controls Inflammation in Mice With Colitis

(2018) Marion Darnaud et al.   GASTROENTEROLOGY

Albumin as a prognostic marker for ulcerative colitis

(2017) Nabeel Khan et al.   WORLD JOURNAL OF GASTROENTEROLOGY

A pathogenic role for T cell–derived IL-22BP in inflammatory bowel disease

(2016) Penelope Pelczar et al.   SCIENCE

Loss of Infliximab Into Feces Is Associated With Lack of Response to Therapy in Patients With Severe Ulcerative Colitis

(2015) Johannan F. Brandse et al.   GASTROENTEROLOGY

IL-22BP is produced by eosinophils in human gut and blocks IL-22 protective actions during colitis

(2015) J C Martin et al.   Mucosal Immunology

Serum regenerating islet-derived 3-alpha is a biomarker of mucosal enteropathies

(2014) I. Marafini et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation

(2013) Atle van Beelen Granlund et al.   CELL AND TISSUE RESEARCH

REG3γ-deficient mice have altered mucus distribution and increased mucosal inflammatory responses to the microbiota and enteric pathogens in the ileum

(2013) L MP Loonen et al.   Mucosal Immunology

Anti-TNF Monoclonal Antibodies in Inflammatory Bowel Disease: Pharmacokinetics-Based Dosing Paradigms

(2012) I Ordás et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Serum albumin concentration: a predictive factor of infliximab pharmacokinetics and clinical response in patients with ulcerative colitis

(2011) A.A. Fasanmade et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Isolation of genes involved in pancreas regeneration by subtractive hybridization

(2010) Jong-Ho Choi et al.   BIOLOGICAL CHEMISTRY

Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis

(2009) Adedigbo A. Fasanmade et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Regulation of C-type Lectin Antimicrobial Activity by a Flexible N-terminal Prosegment

(2008) Sohini Mukherjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE