High‐resolution and quantitative spatial analysis reveal intra‐ductal phenotypic and functional diversification in pancreatic cancer

S100 family proteins are linked to organoid morphology and EMT in pancreatic cancer

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Spatially restricted tumour-associated and host-associated immune drivers correlate with the recurrence sites of pancreatic cancer

(2023) Eva Karamitopoulou et al.   GUT

Cancer statistics, 2022

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Cancer cell states recur across tumor types and form specific interactions with the tumor microenvironment

(2022) Dalia Barkley et al.   NATURE GENETICS

Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment

(2022) William L. Hwang et al.   NATURE GENETICS

Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity

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Spatially confined sub-tumor microenvironments in pancreatic cancer

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Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer

(2021) Srivatsan Raghavan et al.   CELL

Morphological and p40 immunohistochemical analysis of squamous differentiation in endoscopic ultrasound guided fine needle biopsies of pancreatic ductal adenocarcinoma

(2021) Beate Haugk et al.   Scientific Reports

Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution

(2020) Michelle Chan-Seng-Yue et al.   NATURE GENETICS

Role of oncogenic KRAS in the diagnosis, prognosis and treatment of pancreatic cancer

(2020) Louis Buscail et al.   Nature Reviews Gastroenterology & Hepatology

GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer

(2020) Grainne M. O'Kane et al.   CLINICAL CANCER RESEARCH

Basal‐like and classical cells coexist in pancreatic cancer revealed by single‐cell analysis on biopsy‐derived pancreatic cancer organoids from the classical subtype

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A combination of cytokeratin 5/6, p63, p40 and MUC5AC are useful for distinguishing squamous cell carcinoma from adenocarcinoma of the cervix

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Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin

(2020) Elisa Espinet et al.   Cancer Discovery

Integration of Genomic and Transcriptional Features in Pancreatic Cancer Reveals Increased Cell Cycle Progression in Metastases

(2019) Ashton A. Connor et al.   CANCER CELL

Different shades of pancreatic ductal adenocarcinoma, different paths towards precision therapeutic applications

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Morphological classification of pancreatic ductal adenocarcinoma that predicts molecular subtypes and correlates with clinical outcome

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EGFR T790M detection in formalin‐fixed paraffin‐embedded tissues of patients with lung cancer using RNA‐based in situ hybridization: A preliminary feasibility study

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Deciphering DNA methylation signatures of pancreatic cancer and pancreatitis

(2019) Francesco Natale et al.   Clinical Epigenetics

Detection of POLE Subtypes in High-Grade Endometrioid Carcinoma by BaseScope-ISH Assay

(2019) Shuangni Yu et al.   Frontiers in Oncology

Integrated genomic and immunophenotypic classification of pancreatic cancer reveals three distinct subtypes with prognostic/predictive significance

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Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes

(2018) Sebastian Mueller et al.   NATURE

Stratification of Pancreatic Ductal Adenocarcinomas Based on Tumor and Microenvironment Features

(2018) Francesco Puleo et al.   GASTROENTEROLOGY

TP63-Mediated Enhancer Reprogramming Drives the Squamous Subtype of Pancreatic Ductal Adenocarcinoma

(2018) Tim D.D. Somerville et al.   Cell Reports

Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution

(2017) Ann-Marie Baker et al.   Nature Communications

On the Dependency of Cellular Protein Levels on mRNA Abundance

(2016) Yansheng Liu et al.   CELL

GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer

(2016) Paola Martinelli et al.   GUT

Genomic analyses identify molecular subtypes of pancreatic cancer

(2016) Peter Bailey et al.   NATURE

Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation

(2016) Laura Broutier et al.   Nature Protocols

KRAS G12D Mutation Subtype Is A Prognostic Factor for Advanced Pancreatic Adenocarcinoma

(2016) Barbara Bournet et al.   Clinical and Translational Gastroenterology

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma

(2015) Richard A Moffitt et al.   NATURE GENETICS

Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors

(2015) Anneleen Daemen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

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An Immunohistochemical Method to Study Breast Cancer Cell Subpopulations and Their Growth Regulation by Hormones in Three-Dimensional Cultures

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