Sticklac-Derived Natural Compounds Inhibiting RNase H Activity of HIV-1 Reverse Transcriptase

Computational Screening of Inhibitory Compounds for SARS-Cov-2 3CL Protease with a Database Consisting of Approved and Investigational Chemicals

(2023) Kazunori Miwa et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Recent advances on dual inhibitors targeting HIV reverse transcriptase associated polymerase and ribonuclease H

(2023) Jia-Xiong Kang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, and biological evaluation of novel double-winged galloyl derivatives as HIV-1 RNase H inhibitors

(2022) Lina Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity

(2022) Huiyan Lu et al.   Journal of Chemical Information and Modeling

Current medicinal chemistry strategies in the discovery of novel HIV-1 ribonuclease H inhibitors

(2022) Lina Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Small-molecule Inhibitors of HIV-1 Reverse Transcriptase-Associated Ribonuclease H function: Challenges and Recent Developments.

(2021) Valentina Noemi Madia et al.   CURRENT MEDICINAL CHEMISTRY

Analysis of Binding Modes of Antigen–Antibody Complexes by Molecular Mechanics Calculation

(2021) Liang Qu et al.   Journal of Chemical Information and Modeling

Secondary Structure and Conformational Stability of the Antigen Residues Making Contact with Antibodies

(2021) Xinyue Qiao et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Ribonuclease H, an unexploited target for antiviral intervention against HIV and hepatitis B virus

(2019) Enzo Tramontano et al.   ANTIVIRAL RESEARCH

Determinants of Active-Site Inhibitor Interaction with HIV-1 RNase H

(2019) Zhaoyong Xi et al.   ACS Infectious Diseases

ff19SB: Amino-Acid-Specific Protein Backbone Parameters Trained against Quantum Mechanics Energy Surfaces in Solution

(2019) Chuan Tian et al.   Journal of Chemical Theory and Computation

Update on Recent Developments in Small Molecular HIV-1 RNase H Inhibitors (2013-2016): Opportunities and Challenges

(2018) Xueshun Wang et al.   CURRENT MEDICINAL CHEMISTRY

Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase

(2018) Paul L. Boyer et al.   JOURNAL OF VIROLOGY

Design, Synthesis and Biological Evaluation of Novel Galloyl Derivatives as HIV-1 RNase H Inhibitors

(2018) Ping Gao et al.   Chemical Biology & Drug Design

Discovery of 4-oxoquinolines, a new chemical class of anti-HIV-1 compounds

(2018) Tomomi Shiroishi-Wakatsuki et al.   ANTIVIRAL RESEARCH

Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication

(2016) Francesca Esposito et al.   PHYTOMEDICINE

Laccaic Acid A Is a Direct, DNA-competitive Inhibitor of DNA Methyltransferase 1

(2013) Rebecca L. Fagan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Modulation Study of Inhibitory Compounds for Ribonuclease H Activity of Human Immunodeficiency Virus Type 1 Reverse Transcriptase

(2012) Hiroshi Yanagita et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 1. Generalized Born

(2012) Andreas W. Götz et al.   Journal of Chemical Theory and Computation

Discovery of Natural Phenols as G Protein-Coupled Receptor-35 (GPR35) Agonists

(2012) Huayun Deng et al.   ACS Medicinal Chemistry Letters

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural and biochemical study on the inhibitory activity of derivatives of 5-nitro-furan-2-carboxylic acid for RNase H function of HIV-1 reverse transcriptase

(2010) Hiroshi Yanagita et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structural Basis for the Inhibition of RNase H Activity of HIV-1 Reverse Transcriptase by RNase H Active Site-Directed Inhibitors

(2010) H.-P. Su et al.   JOURNAL OF VIROLOGY

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

RNase H Active Site Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Design, Biochemical Activity, and Structural Information

(2009) Thorsten A. Kirschberg et al.   JOURNAL OF MEDICINAL CHEMISTRY

Derivatives of 5-Nitro-furan-2-carboxylic Acid Carbamoylmethyl Ester Inhibit RNase H Activity Associated with HIV-1 Reverse Transcriptase

(2009) Hideyoshi Fuji et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure of HIV-1 Reverse Transcriptase with the Inhibitor β-Thujaplicinol Bound at the RNase H Active Site

(2009) Daniel M. Himmel et al.   STRUCTURE

Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design

(2008) Joseph D. Bauman et al.   NUCLEIC ACIDS RESEARCH