Proteomics-driven Antigen Discovery for Development of Vaccines Against Gonorrhea

The Neisseria gonorrhoeae Obg protein is an essential ribosome-associated GTPase and a potential drug target

(2015) Ryszard A. Zielke et al.   BMC MICROBIOLOGY

Stable isotope labelling methods in mass spectrometry-based quantitative proteomics

(2015) Osama Chahrour et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions

(2015) Carmen Schwechheimer et al.   NATURE REVIEWS MICROBIOLOGY

Multipurpose prevention technologies: the future of HIV and STI protection

(2015) José A. Fernández-Romero et al.   TRENDS IN MICROBIOLOGY

Proteomics of Neisseria gonorrhoeae: the treasure hunt for countermeasures against an old disease

(2015) Benjamin I. Baarda et al.   Frontiers in Microbiology

Global Estimates of the Prevalence and Incidence of Four Curable Sexually Transmitted Infections in 2012 Based on Systematic Review and Global Reporting

(2015) Lori Newman et al.   PLoS One

Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and Future

(2014) M. Unemo et al.   CLINICAL MICROBIOLOGY REVIEWS

Quantitative Proteomics of theNeisseria GonorrhoeaeCell Envelope and Membrane Vesicles for the Discovery of Potential Therapeutic Targets

(2014) Ryszard A. Zielke et al.   MOLECULAR & CELLULAR PROTEOMICS

Reconstitution of a nanomachine driving the assembly of proteins into bacterial outer membranes

(2014) Hsin-Hui Shen et al.   Nature Communications

Recombinant truncated AniA of pathogenic Neisseria elicits a non-native immune response and functional blocking antibodies

(2013) Lucy K. Shewell et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Critical Role for the cccA Gene Product, Cytochrome c2, in Diverting Electrons from Aerobic Respiration to Denitrification in Neisseria gonorrhoeae

(2013) A. C. Hopper et al.   JOURNAL OF BACTERIOLOGY

Enhancement of Adaptive Immunity to Neisseria gonorrhoeae by Local Intravaginal Administration of Microencapsulated Interleukin 12

(2013) Y. Liu et al.   JOURNAL OF INFECTIOUS DISEASES

Suppression of host adaptive immune responses by Neisseria gonorrhoeae: role of interleukin 10 and type 1 regulatory T cells

(2013) Y Liu et al.   Mucosal Immunology

Structural insight into the biogenesis of β-barrel membrane proteins

(2013) Nicholas Noinaj et al.   NATURE

Species-Specificity of the BamA Component of the Bacterial Outer Membrane Protein-Assembly Machinery

(2013) Elena B. Volokhina et al.   PLoS One

Vaccines against gonorrhea: Current status and future challenges

(2013) Ann E. Jerse et al.   VACCINE

Zinc Piracy as a Mechanism of Neisseria meningitidis for Evasion of Nutritional Immunity

(2013) Michiel Stork et al.   PLoS Pathogens

MpeR Regulates themtrEfflux Locus in Neisseria gonorrhoeae and Modulates Antimicrobial Resistance by an Iron-Responsive Mechanism

(2012) Alexandra Dubon Mercante et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel meningococcal 4CMenB vaccine antigens - prevalence and polymorphisms of the encoding genes in Neisseria gonorrhoeae

(2012) Ronza Hadad et al.   APMIS

Developing vaccines in the era of genomics: a decade of reverse vaccinology

(2012) K.L. Seib et al.   CLINICAL MICROBIOLOGY AND INFECTION

TheEscherichia coliPeripheral Inner Membrane Proteome

(2012) Malvina Papanastasiou et al.   MOLECULAR & CELLULAR PROTEOMICS

Discovery of an archetypal protein transport system in bacterial outer membranes

(2012) Joel Selkrig et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Proteomic Analysis of Neisseria gonorrhoeae Biofilms Shows Shift to Anaerobic Respiration and Changes in Nutrient Transport and Outermembrane Proteins

(2012) Nancy J. Phillips et al.   PLoS One

β-Barrel Membrane Protein Assembly by the Bam Complex

(2011) Christine L. Hagan et al.   Annual Review of Biochemistry

Is Neisseria gonorrhoeae Initiating a Future Era of Untreatable Gonorrhea?: Detailed Characterization of the First Strain with High-Level Resistance to Ceftriaxone

(2011) Makoto Ohnishi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Deep sequencing-based analysis of the anaerobic stimulon in Neisseria gonorrhoeae

(2011) Vincent M Isabella et al.   BMC GENOMICS

Proteomic Analysis of theVibrio choleraeType II Secretome Reveals New Proteins, Including Three Related Serine Proteases

(2011) Aleksandra E. Sikora et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomics for development of vaccine

(2011) Monika Adamczyk-Poplawska et al.   Journal of Proteomics

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

The Composition and Metabolic Phenotype of Neisseria gonorrhoeae Biofilms

(2011) Megan L. Falsetta et al.   Frontiers in Microbiology

New Concepts in Immunity to Neisseria Gonorrhoeae: Innate Responses and Suppression of Adaptive Immunity Favor the Pathogen, Not the Host

(2011) Yingru Liu et al.   Frontiers in Microbiology

PSORTb 3.0: improved protein subcellular localization prediction with refined localization subcategories and predictive capabilities for all prokaryotes

(2010) Nancy Y. Yu et al.   BIOINFORMATICS

Lipoproteins of Bacterial Pathogens

(2010) A. Kovacs-Simon et al.   INFECTION AND IMMUNITY

Quantitative Proteomic Analysis of Cell Wall and Plasma Membrane Fractions from Multidrug-ResistantAcinetobacter baumannii

(2010) Sung-Ho Yun et al.   JOURNAL OF PROTEOME RESEARCH

The Gonococcus fights back: is this time a knock out?

(2010) D. A. Lewis   SEXUALLY TRANSMITTED INFECTIONS

Immunization with the recombinant Burkholderia pseudomallei outer membrane protein Omp85 induces protective immunity in mice

(2010) Yu-Ching Su et al.   VACCINE

The influence of genomics and proteomics on the development of potential vaccines against meningococcal infection

(2010) John E Heckels et al.   Genome Medicine

An Outer Membrane Receptor of Neisseria meningitidis Involved in Zinc Acquisition with Vaccine Potential

(2010) Michiel Stork et al.   PLoS Pathogens

Proteomics by Mass Spectrometry: Approaches, Advances, and Applications

(2009) John R. Yates et al.   Annual Review of Biomedical Engineering

A physiologically significant role in nitrite reduction of the CcoP subunit of the cytochrome oxidasecbb3fromNeisseria gonorrhoeae

(2009) Amanda Hopper et al.   FEMS MICROBIOLOGY LETTERS

Phenotypic and genetic characterization of the 2008 WHO Neisseria gonorrhoeae reference strain panel intended for global quality assurance and quality control of gonococcal antimicrobial resistance surveillance for public health purposes

(2009) M. Unemo et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Transcriptional and Functional Analysis of the Neisseria gonorrhoeae Fur Regulon

(2009) L. A. Jackson et al.   JOURNAL OF BACTERIOLOGY

The  -Barrel Outer Membrane Protein Assembly Complex of Neisseria meningitidis

(2009) E. B. Volokhina et al.   JOURNAL OF BACTERIOLOGY

Manganese regulation of virulence factors and oxidative stress resistance in Neisseria gonorrhoeae

(2009) Hsing-Ju Wu et al.   Journal of Proteomics

Crystal structure of lipoprotein GNA1946 from Neisseria meningitidis

(2009) Xue Yang et al.   JOURNAL OF STRUCTURAL BIOLOGY

Transport of lipopolysaccharide across the cell envelope: the long road of discovery

(2009) Natividad Ruiz et al.   NATURE REVIEWS MICROBIOLOGY

A Comprehensive Approach to Identification of Surface-Exposed, Outer Membrane-Spanning Proteins of Leptospira interrogans

(2009) Marija Pinne et al.   PLoS One

Identification and characterization of gonococcal iron transport systems as potential vaccine antigens

(2008) CN Cornelissen   Future Microbiology

Phenotypic and Genotypic Analyses of Neisseria gonorrhoeae Isolates That Express Frequently Recovered PorB PIA Variable Region Types Suggest that Certain P1a Porin Sequences Confer a Selective Advantage for Urogenital Tract Infection

(2008) L. E. Garvin et al.   INFECTION AND IMMUNITY

Bacterial membrane proteomics

(2008) Ansgar Poetsch et al.   PROTEOMICS