Article
Nursing
Lindsay Ellsworth, Julie Sturza, Kate Stanley
Summary: The study revealed that most mothers have limited knowledge about donor human milk and milk banks, and have not received sufficient counseling from medical providers. While participants had positive attitudes towards donor human milk, they tended to choose formula over donor human milk when making decisions. Additionally, if donor human milk was the only option, they preferred milk from a relative or friend over milk banks.
JOURNAL OF HUMAN LACTATION
(2021)
Article
Nutrition & Dietetics
Elena Sinkiewicz-Darol, Urszula Bernatowicz-Lojko, Katarzyna Lubiech, Iwona Adamczyk, Magdalena Twaruzek, Barbara Baranowska, Krzysztof Skowron, Diane L. Spatz
Summary: This study found that milk from tandem breastfeeding mothers had higher fat content, energy value, and total protein concentration compared to milk after weaning, while the carbohydrate content remained stable. The composition of breastmilk changes after weaning to meet the nutritional requirements of the younger child.
Article
Nursing
Jill K. Baird, Shawn M. Jensen, Walter J. Urba, Bernard A. Fox, Jason R. Baird
Summary: The study found that maternal vaccination against SARS-CoV-2 resulted in the presence of protective specific immunoglobulins in human milk that began to significantly increase around 7 days after vaccination, with an IgG-dominant response.
JOURNAL OF HUMAN LACTATION
(2021)
Article
Public, Environmental & Occupational Health
Ann E. Maltby, Belinda C. Odhiambo, Maureen Nyaura, Rosemary Shikari, Emily L. Tuthill
Summary: This study tested a personalized infant feeding support program among perinatal women living with HIV in Kenya. The findings showed that through face-to-face and frequent infant feeding support sessions, women were able to successfully practice exclusive breastfeeding.
Article
Nutrition & Dietetics
Felix Castillo, Felix-Joel Castillo-Ferrer, Begona Cordobilla, Joan Carles Domingo
Summary: A single-center study compared the fatty acids profile, particularly DHA levels, in donor human milk and mother's own milk for preterm infants. The study found that DHA levels were significantly lower in donor human milk compared to mother's own milk, potentially providing inadequate supply of DHA for preterm infants.
Article
Obstetrics & Gynecology
Maya Bunik, Andrea Jimenez-Zambrano, Michael Solano, Brenda L. Beaty, Elizabeth Juarez-Colunga, Xuhong Zhang, Susan L. Moore, Sheana Bull, Jenn A. Leiferman
Summary: This study aimed to explore the impact of a smartphone app called Mother's Milk Messaging (TM) on breastfeeding. Participants were randomized into different groups and their breastfeeding rates, confidence, and social support were observed. The results showed that the app increased women's confidence in breastfeeding and perceived social support. The majority of participants registered the app, and those who engaged with it scored higher over time. Mothers appreciated receiving reliable information through text messages and videos.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Medicine, Research & Experimental
D. Mallardi, C. Tabasso, P. Piemontese, S. Morandi, T. Silvetti, F. Biscarini, P. Cremonesi, B. Castiglioni, V Pica, M. Stuknyte, I De Noni, O. Amato, N. Liotto, F. Mosca, P. Roggero
Summary: The study showed that inoculating PDHM with mother's own milk could restore bacterial growth and personalize the human milk microbiome in PDHM. This personalized effect is beneficial due to the presence of maternal probiotic bacteria in the milk, making PDHM more similar to the mother's own milk.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Nutrition & Dietetics
Ana M. Palacios, Michelle I. Cardel, Erik Parker, Stephanie Dickinson, Valerie R. Houin, Bridget Young, David B. Allison
Summary: This study aimed to evaluate the effectiveness of daily intake of expensive lactation cookies (LCs) on milk production and breastfeeding self-efficacy. The study found no significant effects of LCs on milk production and self-efficacy.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Pasqua Anna Quitadamo, Laura Comegna, Giuseppina Palumbo, Massimiliano Copetti, Paola Lurdo, Federica Zambianco, Maria Assunta Gentile, Antonio Villani
Summary: The study found that the birth rate of twins in the center has almost doubled from 1.28% in 2015 to 2.48% in 2020, with 88% of twins being premature. 18.1% of babies were breastfed for more than 6 months and 6.3% were breastfed for more than 12 months. Infants with lower gestational age and weight, born to multiparous, more mature and medium-high schooling mothers tended to be breastfed for a longer period.
Article
Medicine, General & Internal
Magdalena Sitter, Ulrich Pecks, Mario Ruediger, Sabine Friedrich, Sara Fill Malfertheiner, Alexander Hein, Josefine T. Koenigbauer, Karin Becke-Jakob, Janine Zoellkau, Babett Ramsauer, Katharina Rathberger, Constanza A. Pontones, Katrina Kraft, Patrick Meybohm, Christoph Haertel, Peter Kranke
Summary: Based on data from a comprehensive German surveillance system, this study described the maternal characteristics and clinical presentation of SARS-CoV-2 positive pregnant women requiring intensive care treatment for COVID-19 during pregnancy and the postpartum period.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Pharmacology & Pharmacy
Natalie Dinavitser, Elkana Kohn, Maya Berlin, Nurit Brandriss, Adina Bar-Chaim, Rimona Keidar, Ayelet Livne, David Stepensky, Matitiahu Berkovitch, Revital Sheinberg
Summary: This study examined the excretion of levetiracetam in breastmilk in breastfeeding women with epilepsy, finding that exposure to the drug in breastmilk may lead to infant toxicities. The study also revealed a close correlation between levetiracetam dose, maternal serum concentration, and breastmilk levels. Further studies are needed to assess the short- and long-term safety of levetiracetam in breastfeeding infants.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Medicine, Research & Experimental
Parul Singh, Noora Al Mohannadi, Selvasankar Murugesan, Fajr Almarzooqi, Basirudeen Syed Ahamed Kabeer, Alexandra Katharina Marr, Tomoshige Kino, Tobias Brummaier, Annalisa Terranegra, Rose McGready, Francois Nosten, Damien Chaussabel, Souhaila Al Khodor
Summary: This study investigated the microbial communities in breast milk of mothers with preterm deliveries and found that the microbial communities became increasingly diverse and distinct as the breast milk matured. There were significant differences in the community structures between preterm and term breast milk samples. This study highlights the significant influence of pregnancy-related complications on the composition and diversity of breast milk microbiota, paving the way for improving maternal and infant health outcomes.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Article
Immunology
Carsten Hagenbeck, Janine Zoellkau, Martina Helbig, Tanja Fehm, Nora K. Schaal
Summary: In Germany, pregnant and breastfeeding women were not included in the registration studies of COVID-19 vaccines, resulting in a delayed official recommendation for this vulnerable group. The survey revealed that the majority of participants obtained information about the recommendation autonomously (61.6%) and through the media (56.9%). Vaccination uptake increased after the official recommendation, but the involvement of healthcare professionals and education campaigns focusing on scientific evidence should be enhanced.
Article
Nutrition & Dietetics
Dominick J. Lemas, Xinsong Du, Bethany Dado-Senn, Ke Xu, Amanda Dobrowolski, Marina Magalhaes, Juan J. Aristizabal-Henao, Bridget E. Young, Magda Francois, Lindsay A. Thompson, Leslie A. Parker, Josef Neu, Jimena Laporta, Biswapriya B. Misra, Ismael Wane, Samih Samaan, Timothy J. Garrett
Summary: This study aims to identify unique metabolites that may impact infant health outcomes by analyzing the metabolome of human and bovine milk at 2 weeks of life. The results showed that more than 80% of the milk metabolome is shared between human and bovine milk during early lactation. These findings highlight untargeted metabolomics as a potential strategy to identify unique and shared metabolites in bovine and human milk that may relate to and impact infant health outcomes.
Article
Nursing
Hannah G. Juncker, Michelle Romijn, Veerle N. Loth, Eliza J. M. Ruhe, Sjors Bakker, Saskia Kleinendorst, Christianne J. M. de Groot, Dasja Pajkrt, Aniko Korosi, Johannes B. van Goudoever, Marit J. van Gils, Britt J. van Keulen
Summary: In lactating mothers in the Netherlands, 23.1% of human milk contains IgA antibodies against SARS-CoV-2. This suggests that many breastfed infants may receive passive immunity and protection against COVID-19.
JOURNAL OF HUMAN LACTATION
(2021)
Article
Medicine, General & Internal
Janine Zoellkau, Laura Swiderski, Alexander Schmidt, Friederike Weschenfelder, Tanja Groten, Dirk Hoyer, Uwe Schneider
Summary: This study found that gestational diabetes can alter fetal autonomic control, increase fetal vagal tone, and have a positive correlation with maternal blood glucose levels and birth weight. However, there wasn't a significant correlation between fetal movement index and birth weight, but it did attenuate the positive correlation between maternal blood glucose levels and birth weight.
JOURNAL OF CLINICAL MEDICINE
(2021)
Letter
Obstetrics & Gynecology
Stefan Gloeckner, Franziska Hornung, Yvonne Heimann, Ekkehard Schleussner, Stefanie Deinhardt-Emmer, Bettina Loeffler, Janine Zoellkau
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Medicine, General & Internal
Magdalena Sitter, Ulrich Pecks, Mario Ruediger, Sabine Friedrich, Sara Fill Malfertheiner, Alexander Hein, Josefine T. Koenigbauer, Karin Becke-Jakob, Janine Zoellkau, Babett Ramsauer, Katharina Rathberger, Constanza A. Pontones, Katrina Kraft, Patrick Meybohm, Christoph Haertel, Peter Kranke
Summary: Based on data from a comprehensive German surveillance system, this study described the maternal characteristics and clinical presentation of SARS-CoV-2 positive pregnant women requiring intensive care treatment for COVID-19 during pregnancy and the postpartum period.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Microbiology
Janine Zoellkau, Juliane Ankert, Mathias W. Pletz, Sasmita Mishra, Gregor Seliger, Silvia M. Lobmaier, Clarissa U. Prazeres Da Costa, Vera Seidel, Katharina von Weizsaecker, Alexandra Jablonka, Christian Dopfer, Michael Baier, Thomas Horvatits, Ingrid Reiter-Owona, Tanja Groten, Benjamin T. Schleenvoigt
Summary: No increased risk of HEV exposure or serological signs of schistosomiasis or echinococcosis exposure could be observed in pregnant migrants in Germany. The anti-HEV serology status did not have an influence on fetal growth restriction.
Article
Obstetrics & Gynecology
Richard Biedermann, Ekkehard Schleussner, Angela Lauten, Yvonne Heimann, Thomas Lehmann, Hans Proquitte, Friederike Weschenfelder
Summary: This study aimed to evaluate the effects of the timing of antenatal corticosteroids on neonatal outcomes in preterm infants. The results showed that a prolonged ACS-to-delivery interval was associated with an increased risk of respiratory complications, especially in VLBW infants.
GEBURTSHILFE UND FRAUENHEILKUNDE
(2022)
Article
Multidisciplinary Sciences
Sophia K. Johnson, Jana Pastuschek, Daniel C. Benyshek, Yvonne Heimann, Anne Moeller, Juergen Roedel, Jacob White, Janine Zoellkau, Tanja Groten
Summary: This study investigated the health trend of postpartum ingestion of placenta and its potential risks on neonatal health. Results suggest that processed placenta preparations are unlikely to be a source of clinical infection.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Luiz Gustavo dos Anjos Borges, Jana Pastuschek, Yvonne Heimann, Kristin Dawczynski, Ekkehard Schleussner, Dietmar H. Pieper, Janine Zollkau
Summary: This study aims to evaluate the vaginal microbial composition of PPROM patients and its development under standard antibiotic therapy, as well as to assess the usefulness of vaginal microbiota for the prediction of EONS. The study also examines the neonatal microbiota at birth as a possible reflection of in utero microbiota. The findings suggest that analyzing vaginal and neonatal microbiota through 16S rRNA gene sequencing can be a basis for individualized risk assessment for consecutive EONS.
Article
Medicine, General & Internal
Friederike Weschenfelder, Janine Zoellkau, Anna Schohe, Ulrich Pecks, Tanja Groten, Ute Schaefer-Graf
Summary: This study aims to investigate whether obesity is an independent risk factor for severe maternal and neonatal outcomes in pregnant women with COVID-19. The results showed that obesity was significantly associated with gestational diabetes, hypertensive pregnancy disorders, and higher rates of C-sections. BMI was identified as a predictor for severe outcomes such as maternal or neonatal death and preterm delivery (<32 weeks).
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Claudia Riess, Yvonne Heimann, Ekkehard Schleussner, Tanja Groten, Friederike Weschenfelder
Summary: This study aims to investigate the impact of gestational diabetes on the well-being of pregnant women, as well as their sensitivities and illness perceptions. It is hypothesized that the burden of illness might be related to pre-existing mental distress. A survey and psychological assessment of patients treated for gestational diabetes revealed an association between mental distress and well-being during treatment. Screening for mental health problems during pregnancy should be considered to target psychologically distressed patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Immunology
Carsten Hagenbeck, Janine Zoellkau, Martina Helbig, Tanja Fehm, Nora K. Schaal
Summary: In Germany, pregnant and breastfeeding women were not included in the registration studies of COVID-19 vaccines, resulting in a delayed official recommendation for this vulnerable group. The survey revealed that the majority of participants obtained information about the recommendation autonomously (61.6%) and through the media (56.9%). Vaccination uptake increased after the official recommendation, but the involvement of healthcare professionals and education campaigns focusing on scientific evidence should be enhanced.
Article
Obstetrics & Gynecology
Katharina Germeshausen, Aissa Linzbach, Janine Zoellkau, Yvonne Heimann, Ekkehard Schleussner, Tanja Groten, Friederike Weschenfelder
Summary: The purpose of this study was to compare the efficacy of intramuscular and intravenous administration of meptazinol in relieving labor pain. The results showed that meptazinol significantly reduced labor pain regardless of the method of administration. However, the study also found a potentially poorer perinatal outcome.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
Article
Endocrinology & Metabolism
Sophie Bastobbe, Yvonne Heimann, Ekkehard Schleussner, Tanja Groten, Friederike Weschenfelder
Summary: Flash glucose monitoring (FGM) has been approved for pregnant women with preexisting diabetes since 2017, but its use in gestational diabetes (GDM) has been a topic of debate. The lack of accuracy and recommended target values are the main concerns against using FGM in GDM. This pilot study analyzed the impact of FGM on pregnancy outcomes, patient satisfaction, and confirmed the safety of its use in GDM pregnancies.
ACTA DIABETOLOGICA
(2023)
