Epigenetic and transcriptional landscapes during cerebral cortex development in a microcephaly mouse model

Gadd45g, A Novel Antidepressant Target, Mediates Metformin-Induced Neuronal Differentiation of Neural Stem Cells Via DNA Demethylation

(2022) Le Zhang et al.   STEM CELLS

Multifaceted Microcephaly-Related Gene MCPH1

(2022) Martina Kristofova et al.   Cells

Zika virus vertical transmission in interferon receptor1-antagonized Rag1−/− mice results in postnatal brain abnormalities and clinical disease

(2022) Clayton W. Winkler et al.   Acta Neuropathologica Communications

CACNA1I gain-of-function mutations differentially affect channel gating and cause neurodevelopmental disorders

(2021) Yousra El Ghaleb et al.   BRAIN

LINGO3 regulates mucosal tissue regeneration and promotes TFF2 dependent recovery from colitis

(2021) Kelly M. Zullo et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Central Alteration in Peripheral Neuropathy of Trembler-J Mice: Hippocampal pmp22 Expression and Behavioral Profile in Anxiety Tests

(2021) Juan Pablo Damián et al.   Biomolecules

Comparative Milestones in Rodent and Human Postnatal Central Nervous System Development

(2021) Caroline J. Zeiss   TOXICOLOGIC PATHOLOGY

Endothelin-1 signaling maintains glial progenitor proliferation in the postnatal subventricular zone

(2020) Katrina L. Adams et al.   Nature Communications

Topoisomerase 3β knockout mice show transcriptional and behavioural impairments associated with neurogenesis and synaptic plasticity

(2020) Yuyoung Joo et al.   Nature Communications

Multi-Omics Characterization of Inflammatory Bowel Disease-Induced Hyperplasia/Dysplasia in the Rag2−/−/Il10−/− Mouse Model

(2020) Qiyuan Han et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting epigenetic modifications in cancer therapy: erasing the roadmap to cancer

(2019) Helai P. Mohammad et al.   NATURE MEDICINE

TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells

(2019) Kasper D. Rasmussen et al.   GENOME RESEARCH

Elucidation of the phenotypic spectrum and genetic landscape in primary and secondary microcephaly

(2019) Paranchai Boonsawat et al.   GENETICS IN MEDICINE

Genome-Wide Alteration of 5-Hydroxymethylcytosine in Hypoxic-Ischemic Neonatal Rat Model of Cerebral Palsy

(2019) Yunpeng Zhang et al.   Frontiers in Molecular Neuroscience

Overlapping functions of Krüppel-like factor family members: targeting multiple transcription factors to maintain the naïve pluripotency of mouse embryonic stem cells

(2018) Mariko Yamane et al.   DEVELOPMENT

Cadherin 8 regulates proliferation of cortical interneuron progenitors

(2018) Fani Memi et al.   Brain Structure & Function

Functions and mechanisms of epigenetic inheritance in animals

(2018) Ksenia Skvortsova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epilepsy-causing sequence variations in SIK1 disrupt synaptic activity response gene expression and affect neuronal morphology

(2016) Christoph Pröschel et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Whole-genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver

(2016) Xin Li et al.   GENOME RESEARCH

Tet3 Reads 5-Carboxylcytosine through Its CXXC Domain and Is a Potential Guardian against Neurodegeneration

(2016) Seung-Gi Jin et al.   Cell Reports

MCPH1 maintains long-term epigenetic silencing ofANGPT2in chronic lymphocytic leukemia

(2015) Pradeep Kumar Kopparapu et al.   FEBS Journal

A case report: Autosomal recessive microcephaly caused by a novel mutation in MCPH1 gene

(2015) Soudeh Ghafouri-Fard et al.   GENE

Dystroglycan Binding to α-Neurexin Competes with Neurexophilin-1 and Neuroligin in the Brain

(2014) Carsten Reissner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The emerging role of 5-hydroxymethylcytosine in neurodegenerative diseases

(2014) Sahar Al-Mahdawi et al.   Frontiers in Neuroscience

Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease

(2013) Fengli Wang et al.   HUMAN MOLECULAR GENETICS

Epigenetic changes in the progression of Alzheimer's disease

(2013) M.A. Bradley-Whitman et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Wnt7a Regulates Multiple Steps of Neurogenesis

(2013) Q. Qu et al.   MOLECULAR AND CELLULAR BIOLOGY

Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain

(2013) Natacha Coppieters et al.   NEUROBIOLOGY OF AGING

Global Epigenomic Reconfiguration During Mammalian Brain Development

(2013) R. Lister et al.   SCIENCE

Neuritin 1 promotes neuronal migration

(2012) Arianna Zito et al.   Brain Structure & Function

Mutations inCCDC39andCCDC40are the Major Cause of Primary Ciliary Dyskinesia with Axonemal Disorganization and Absent Inner Dynein Arms

(2012) Dinu Antony et al.   HUMAN MUTATION

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles

(2012) Altuna Akalin et al.   GENOME BIOLOGY

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications

(2011) Felix Krueger et al.   BIOINFORMATICS

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

(2011) Junjie U. Guo et al.   CELL

Genome-wide Regulation of 5hmC, 5mC, and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells

(2011) Yufei Xu et al.   MOLECULAR CELL

MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1–Cdc25 pathway

(2011) Ralph Gruber et al.   NATURE CELL BIOLOGY

Neuronal activity modifies the DNA methylation landscape in the adult brain

(2011) Junjie U Guo et al.   NATURE NEUROSCIENCE

Pax6 Is a Human Neuroectoderm Cell Fate Determinant

(2010) Xiaoqing Zhang et al.   Cell Stem Cell

Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail

(2010) Yingying Zhang et al.   NUCLEIC ACIDS RESEARCH

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

BRIT1/MCPH1 links chromatin remodelling to DNA damage response

(2009) Guang Peng et al.   NATURE CELL BIOLOGY

Gradients in the Brain: The Control of the Development of Form and Function in the Cerebral Cortex

(2009) S. N. Sansom et al.   Cold Spring Harbor Perspectives in Biology

DNA methylation and gene expression

(2009) Zahava Siegfried et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

The transcription factor Nfix is essential for normal brain development

(2008) Christine E Campbell et al.   BMC DEVELOPMENTAL BIOLOGY

A core Klf circuitry regulates self-renewal of embryonic stem cells

(2008) Jianming Jiang et al.   NATURE CELL BIOLOGY