Elucidating the clandestine behavior of enantiomeric DHPs in calcium channels

Modulation of Pore Opening of Eukaryotic Sodium Channels by π-Helices in S6

(2023) Koushik Choudhury et al.   Journal of Physical Chemistry Letters

Mechanisms of dihydropyridine agonists and antagonists in view of cryo-EM structures of calcium and sodium channels

(2023) Denis B. Tikhonov et al.   JOURNAL OF GENERAL PHYSIOLOGY

An open state of a voltage-gated sodium channel involving a π-helix and conserved pore-facing asparagine

(2021) Koushik Choudhury et al.   BIOPHYSICAL JOURNAL

Structural Basis of the Modulation of the Voltage‐Gated Calcium Ion Channel Ca v 1.1 by Dihydropyridine Compounds**

(2020) Shuai Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca2+ Channel

(2019) Yanyu Zhao et al.   CELL

Cryo-EM structures of apo and antagonist-bound human Cav3.1

(2019) Yanyu Zhao et al.   NATURE

Evolutionary Origin of a Secondary Structure: π-Helices as Cryptic but Widespread Insertional Variations of α-Helices That Enhance Protein Functionality

(2010) Richard B. Cooley et al.   JOURNAL OF MOLECULAR BIOLOGY

The elusive π-helix

(2010) R. Peter Riek et al.   JOURNAL OF STRUCTURAL BIOLOGY

The π-helix translates structure into function

(2010) Todd M. Weaver   PROTEIN SCIENCE