Article
Chemistry, Applied
Arianna Tota, Marco Colella, Claudia Carlucci, Andrea Aramini, Guy Clarkson, Leonardo Degennaro, James A. Bull, Renzo Luisi
Summary: A new method for synthesizing hydrazinium salts under mild and simple conditions, tolerant to other functional groups including bioactive molecules, was reported. Insights on the structure of hydrazinium salts were provided by X-ray analysis.
ADVANCED SYNTHESIS & CATALYSIS
(2021)
Article
Chemistry, Multidisciplinary
Jie Cui, Xin Zhang, Hongwei Huang, Man Yang, Bian Yang, Qing Yang, Shuhua Liang, Shaodong Sun
Summary: The mechanism of facet junction-dependent photocharge separation in polyhedral Cu2O is demonstrated, and the impact of different facet junctions on photodegradation activity is compared. The results reveal that hierarchical facet junctions are formed in 50-faceted Cu2O, leading to more efficient photocharge separation.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Chemistry, Physical
Muhammad Tayyab, Bernard Jomari Razote, Chang-Ha Lee
Summary: The surface or interface facets design is a versatile strategy to improve essential catalytic features to enhance efficiency.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Shenghao Yang, Yonglong Zheng, Guangyu He, Mengmeng Zhang, Hongyan Li, Yawen Wang, Hongyu Chen
Summary: This paper describes the synthesis of gold nanoparticles with rhombic dodecahedron shapes and deep cavities through the use of triangular nanoplates. An unusual growth method that combines ligand-promoted facet-selective growth and site-specific deposition is proposed. This templateless growth not only allows for high defect-tolerance, but also expands synthetic control at the nanoscale.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Bang Gong, Enhe Bai, Xueqiong Feng, Liwei Yi, Yeji Wang, Xin Chen, Xiangcheng Zhu, Yanwen Duan, Yong Huang
Summary: Metals play critical roles in life by coordinating with various molecules, proteins, and nucleic acids. This paragraph discusses the discovery of a new Cu(II)-binding natural product, chalkophomycin, with a unique asymmetric square-coordination system, which could potentially inspire the synthesis of Cu(II) chelators for neurodegenerative diseases or Cu(II)-based antitumor therapeutics.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Daniel Joven-Sancho, Miguel Baya, Antonio Martin, Jesus Orduna, Babil Menjon
Summary: By utilizing suitable synthetic procedures, researchers isolated square-planar organosilver(III) compounds and determined their geometry and stereochemistry. The experimentally obtained compounds exhibit kinetic preference for specific stereoisomers and show a tendency to form rare five-coordinate Ag-III species. Additionally, a unique silver(III) derivative with trigonal bipyramidal geometry and inverted ligand field has been identified for the first time.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Chenxi Qiu, Qiang Zhou, Rui Gao, Yizheng Guo, Jiaqi Qin, Dongqi Wang, Yujiang Song
Summary: In this study, we report the synthesis of a novel electrocatalyst for the ascorbic acid oxidation reaction (AAOR) in direct ascorbic acid fuel cells (DAAFCs). The CeO2 nanoparticles evenly distributed on carbon black show remarkable AAOR activity, attributed to the surface Ce3+ of CeO2. Additionally, CeO2/C can capture the electrons generated by AAOR, protecting the -COOH and -C=O sites from being reduced. The DAAFCs fabricated with CeO2/C exhibit a remarkable power density.
Article
Chemistry, Multidisciplinary
Jan Sietmann, Marius Tenberge, Johannes M. Wahl
Summary: Methylenecyclobutanes can undergo Wacker oxidation via a semi-pinacol-type rearrangement. The use of tert-butyl nitrite as oxidant ensures efficient catalyst turn-over and high Markovnikov-selectivity under mild conditions, leading to the synthesis of cyclopentanones in good yield and excellent selectivity. By introducing a pyox ligand to palladium, the first enantioselective Wacker oxidation of prochiral methylenecyclobutanes is achieved.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Yu Jin Heo, Hyun Tae Kim, Ashok Kumar Jaladi, Duk Keun An
Summary: This study introduces a reliable method for the chemoselective partial reduction of tertiary amides to aldehydes using commercially available DIBALH reagent in the presence of easily reducible ester groups. The method was successfully extended to multi-functional molecules bearing ester groups, achieving selective reduction to the corresponding aldehydes.
Article
Chemistry, Physical
Hongyuan Yang, J. Niklas Hausmann, Viktor Hlukhyy, Thomas Braun, Konstantin Laun, Ingo Zebger, Matthias Driess, Prashanth W. Menezes
Summary: This study developed a novel ternary intermetallic CaFe6Ge6 precatalyst, which can transform into a porous ultrathin Ca-Fe-O heteroshell structure during alkaline OER. The material exhibits a large electrochemical surface area and more exposed active Fe sites, benefiting from synergistic effects. Additionally, the presence of Ca in Ca-Fe-O enhances the transport and activation of hydroxyls and related OER reaction intermediates.
Article
Biochemistry & Molecular Biology
Goran Kragol, Victoria A. Steadman, Zorica Marusic Istuk, Ana Cikos, Martina Bosnar, Dubravko Jelic, Gabrijela Ergovic, Marija Trzun, Berislav Bosnjak, Ana Bokulic, Jasna Padovan, Ines Glojnaric, Vesna Erakovic Haber
Summary: This study reveals a novel azithromycin analog with good anti-inflammatory properties obtained via Barton-McCombie oxidation, which has the potential to treat chronic inflammatory diseases.
Article
Chemistry, Organic
Showkat Ahmad Bhat, Mohammad Yaqoob Bhat, Suhail A. Rather, Ifshana Gani, Khursheed Ahmad Bhat, Qazi Naveed Ahmed
Summary: An efficient strategy for N-formylation of amides and oxidation of indolines to isatins using readily available reagents has been described. This method exhibits operational simplicity, excellent functional group tolerance, broad substrate scope, and fast kinetics. Furthermore, it has been successfully applied to the synthesis of the natural product alatamide. Notably, DMSO plays three important roles as a formyl group source, an oxidant, and a solvent.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Chemistry, Organic
Jinwu Zhao, Zhigao Luo, Yipeng Liu, Jingxiu Xu, Zunnan Huang, Wenfang Xiong
Summary: Visible light mediated oxidation of alcohols to ketones or aldehydes is achieved using anthraquinone as a catalyst, DMSO as an oxidant, and irradiation at 430-440 nm at room temperature. The study investigates key parameters such as irradiating wavelength, reaction medium, and photocatalyst. The protocol offers a transition metal-free and mild reaction conditions for the oxidation of alcohols.
Article
Chemistry, Organic
Stephonda G. Lewis, Abra G. Dadum, David McLean, Jhennalin Buenavista, Jaileen Myers, Kyle M. Lambert, Justin D. Fair
Summary: The oxidation of alcohols in the presence of reactive amines using the commercially available oxoammonium cation, Bobbitt's salt, is reported. The oxidation is carried out under acidic conditions, and subsequent treatment with a suitable base provides a convenient one-pot method for the synthesis of imines with high yields (74-99%).
Article
Chemistry, Multidisciplinary
Sanjeevan Rajagopal, Suresh Thangudu, Kuo Chu Hwang
Summary: Direct alcohol fuel cells have a promising future and require development of highly active electrocatalysts for alcohol oxidation. High-index facet nanomaterials show promise for successful alcohol oxidation, but their fabrication and exploration are rarely reported. We successfully synthesized a high-index facet {711} Au 12 tip nanostructure using a cationic surfactant and found that it exhibited significantly higher electrocatalytic activity and CO tolerance compared to low-index facet Au nanoparticles. These findings suggest that high-index facet Au nanomaterials are ideal electrode materials for alcohol electrooxidation in fuel cells.
Article
Chemistry, Organic
Smruti Ranjan Mohanty, Namrata Prusty, Shyam Kumar Banjare, Tanmayee Nanda, Ponneri C. Ravikumar
Summary: An earth-abundant and inexpensive Mn(I)-catalyzed alkylation of 2-pyridone with maleimide has been reported for the first time, which demonstrates an unexpected rearrangement in the presence of acetic acid and provides a unique class of compounds. This methodology shows good tolerance towards various functional groups, delivering the alkylated products in moderate to excellent yields.
Article
Chemistry, Multidisciplinary
Bedadyuti Vedvyas Pati, Asit Ghosh, Komal Yadav, Shyam Kumar Banjare, Shalini Pandey, Upakarasamy Lourderaj, Ponneri C. Ravikumar
Summary: The stereoselective synthesis of 1,3-enynes from 1,3-diynes was achieved by palladium-catalyzed selective C-C bond cleavage of cyclopropanol. The protocol showed high stereoselectivity with diverse substrates. Mechanistic investigations and DFT calculations were carried out to validate the atomic-level mechanism and identify rate-controlling states in the catalytic cycle. Preliminary investigations ruled out the involvement of the radical pathway in this transformation.
Review
Engineering, Environmental
Neha Badola, Ashish Bahuguna, Yoel Sasson, Jaspal Singh Chauhan
Summary: Microplastics are a growing threat to the environment, especially in water ecosystems. Scientists are researching various methods to remove microplastics, but there are limitations to their efficiency and applicability in different environmental conditions. Additionally, implementing governmental policies and regulations against microplastics remains a challenging task. This review aims to provide an overview of effective microplastic removal methods, compare their mechanisms and limitations, and discuss global policies and regulations. The review also highlights research gaps and recent advancements in the field.
FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING
(2022)
Article
Chemistry, Organic
Smruti Ranjan Mohanty, Namrata Prusty, Tanmayee Nanda, Shyam Kumar Banjare, Ponneri C. Ravikumar
Summary: In this study, the ruthenium-catalyzed regioselective sp2(C-H) monoalkenylation of N-arylpyridones was demonstrated, where the pyridone served as a weakly coordinating directing group. Importantly, this methodology was effectively applied to the synthesis of various drug analogues, with high yields up to 93%. HRMS analysis also revealed the presence of a six-membered ruthenium complex.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Gopal Krushna Das Adhikari, Bedadyuti Vedvyas Pati, Smruti Ranjan Mohanty, Namrata Prusty, Ponneri C. Ravikumar
Summary: A highly regio- and stereoselective synthesis of the core skeleton of hexahydrobenzo[c]phenanthridine-type alkaloids using Co(acac)(2) at room temperature is reported. The reaction shows compatibility for a wide range of substrates and provides good to excellent yield of products.
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Bedadyuti Vedvyas Pati, Shyam Kumar Banjare, Gopal Krushna Das Adhikari, Tanmayee Nanda, Ponneri C. Ravikumar
Summary: In this study, a Rh(III) catalyzed synthesis of alkynylated and bis-isocoumarin compounds from 1,3-dialkyne was reported. Exclusive one-pot formation of 3,3-bis-isocoumarin isomers was achieved, eliminating several other possibilities. This is the first example of transition metal catalyzed synthesis of alkynylated and bis-isocoumarin scaffolds, and the protocol is compatible with a wide range of functional groups.
Article
Chemistry, Organic
Namrata Prusty, Smruti Ranjan Mohanty, Shyam Kumar Banjare, Tanmayee Nanda, Ponneri C. Ravikumar
Summary: A Ni-catalyzed cascade reaction between 2-pyridone and alkynes has been achieved by tuning reaction conditions and incorporating a directing group. The use of sodium iodide as an additive plays a crucial role in the success of this transformation. The detection of a five-membered metallacycle intermediate through HRMS provides insights into the reaction mechanism.
Review
Chemistry, Physical
Tanmayee Nanda, Muhammed Fastheem, Astha Linda, Bedadyuti Vedvyas Pati, Shyam Kumar Banjare, Pragati Biswal, Ponneri C. Ravikumar
Summary: In recent years, the strong C-C bond activation catalyzed by transition metals has gained significant attention in the field of synthetic chemistry. This protocol allows for the simultaneous and direct functionalization of two different M-C bonds. Among various strategies for C-C bond activation, strain-driven C-C bond activation has enabled otherwise challenging transformations. Palladium catalysts have been extensively explored and utilized due to their robust reactivity and selectivity. In this article, we briefly discuss the palladium-catalyzed C-C bond activation of three- and four-membered cycloalkane derivatives.
Article
Chemistry, Multidisciplinary
Pragati Biswal, Tanmayee Nanda, Shyam Kumar Banjare, Smruti Ranjan Mohanty, Ranjit Mishra, Ponneri C. Ravikumar
Summary: This article reports a novel reaction method for the highly stereoselective C(sp(2))-H propenylation using N-allyl benzimidazole as a catalyst. Detailed mechanistic studies were conducted to understand the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Applied
Shyam Kumar Banjare, Saista Afreen, Pranav Shridhar Mahulkar, Annapurna Saxena, Ponneri C. Ravikumar
Summary: Here, we report the reactivity of cobalt(III)-catalyst towards hydroarylative functionalization of 1,6-diyne, and unveil the reaction mechanism and the involvement of an ionic pathway.
ADVANCED SYNTHESIS & CATALYSIS
(2023)
Article
Chemistry, Organic
Pragati Biswal, Tanmayee Nanda, Namrata Prusty, Smruti Ranjan Mohanty, Ponneri C. Ravikumar
Summary: A rhodium-catalyzed oxidative C-H/N-H dehydrogenative[3 + 2] annulation strategy has been developed for the synthesis of 2-methylindole scaffolds by reacting anilines and N-allylbenzimidazole. This transformation involves the cleavage of the thermodynamically stable C-N bond of allylamine and proceeds through a cascade of C(sp(2))-H alkylation followed by intramolecular cyclization. Detailed mechanistic studies have been performed to identify a key intermediate.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Tanmayee Nanda, Shubham Kumar Dhal, Gopal Krushna Das Adhikari, Namrata Prusty, Ponneri C. Ravikumar
Summary: We have demonstrated a rhodium-catalyzed carboamination of olefin with the double bond intact. For the first time, deacylative carboamination of the maleimide has been achieved using phenoxyacetamide as the aminating source. We have also disclosed a C-H olefination protocol where the maleimide group is successfully installed in the ortho-position of phenoxyacetamide, utilizing phenoxyacetamide as a traceless directing group with in situ release of acetamide. Base-assisted E2-elimination plays a key role in the success of the olefination reaction.
CHEMICAL COMMUNICATIONS
(2023)
Review
Chemistry, Organic
Bedadyuti Vedvyas Pati, Nitha Nahan Puthalath, Shyam Kumar Banjare, Tanmayee Nanda, Ponneri C. C. Ravikumar
Summary: This review provides an overview of recent developments in transition metal-catalyzed C-H/C-C bond activation and coupling with 1,3-diynes for assembling alkynylated heterocycles, bis-heterocycles, and 1,3-enynes. The use of 1,3-diynes has received significant attention due to its ability to easily form bis-heterocycles. The strategy of C-H activation and subsequent reaction with 1,3-diynes has potential for larger-scale synthesis in the pharmaceutical industry.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Tanmayee Nanda, Asish Dharmendra Shukla, Shubham Kumar Dhal, Muhammed Fastheem, Ponneri C. Ravikumar
Summary: In this study, biologically active scaffolds, azetidinones or benzoxazepines, were synthesized through a series of reactions catalyzed by N-heterocyclic carbene. The key intermediate acylazolium species in this reaction is generated through C-C bond cleavage of cyclopropenone, which is different from previous N-heterocyclic carbene catalysis. Two different bio-active skeletons, beta-lactam and benzoxazepine, were successfully synthesized using N-heterocyclic carbene as the catalyst.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Multidisciplinary
Shyam Kumar Banjare, Pranav Shridhar Mahulkar, Tanmayee Nanda, Bedadyuti Vedvyas Pati, Lamphiza O. Najiar, Ponneri C. Ravikumar
Summary: Alkynes play a crucial role as coupling partners in transition metal-catalysed reactions. Their ability to effectively coordinate with metal d-orbitals makes them highly versatile for the synthesis of valuable organic molecules. Despite extensive research, there is still a lot more to explore in terms of the reactivity of alkynes and their potential applications.
CHEMICAL COMMUNICATIONS
(2022)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
