Article
Pharmacology & Pharmacy
Bettina Quintanilha Magalhaes, Francisco P. Machado, Paola S. Sanches, Barbara Lima, Deborah Quintanilha Falcao, Natalia von Ranke, Murilo Lamim Bello, Carlos Rangel Rodrigues, Marcelo Guerra Santos, Leandro Rocha, Robson X. Faria
Summary: The study found that Eugenia sulcata essential oil and its nanoemulsion have inhibitory effects on P2X7R activity and can reverse inflammatory response. The main substance, beta-caryophyllene, showed a high inhibitory effect but may have toxic effects on humans. This research provides insights for the development of new anti-inflammatory therapies.
Article
Engineering, Chemical
Mariana M. B. Azevedo, Catia A. Almeida, Francisco C. M. Chaves, Eduardo Ricci-Junior, Andreza R. Garcia, Igor A. Rodrigues, Celuta S. Alviano, Daniela S. Alviano
Summary: This study successfully developed a stable nanoemulsion NECC with antifungal activity, which showed good inhibitory effects against Mucor ramosissimus and Candida albicans. The nanoemulsion also demonstrated potential to inhibit fungal extracellular proteases, while showing no hemolytic effect at the highest concentration tested.
Article
Chemistry, Applied
Kai Huang, Runan Liu, Ying Zhang, Xiao Guan
Summary: The study indicates that the prepared cedarwood essential oil nanoemulsion has smaller particle size and higher zeta potential value compared to the Pickering emulsion, with better stability. Both nanoemulsion and Pickering emulsion show higher antioxidant, iron reducing, and antibacterial activities than the cedarwood essential oil itself.
Article
Multidisciplinary Sciences
Yeo-Jin Jeong, Hee-Eun Kim, Su-Jin Han, Jun-Seon Choi
Summary: The study demonstrated that nanoemulsified cinnamon essential oil effectively inhibited the maturation of multi-species oral biofilms and the growth of oral microorganisms, including aciduric bacteria that cause dental caries.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Amr M. Shehabeldine, Ahmed S. Doghish, Walaa A. El-Dakroury, Mahmoud M. H. Hassanin, Abdulaziz A. Al-Askar, Hamada AbdElgawad, Amr H. Hashem
Summary: In this study, clove oil nanoemulsion (CL-nanoemulsion) and emulsion (CL-emulsion) were prepared using an ecofriendly method. The CL-nanoemulsion showed antibacterial, antifungal, anti-biofilm, and anticancer properties, with minimal inhibitory concentration (MIC) values between 0.31 and 5 mg/mL against bacteria and significant antifungal activity against various fungal strains. The CL-nanoemulsion also exhibited lower IC50 values in MCF-7 breast cancer cells compared to CL-emulsion, indicating its potential as an anticancer agent.
Article
Biochemistry & Molecular Biology
Mohamed F. Abdelhameed, Gihan F. Asaad, Tamer I. M. Ragab, Rania F. Ahmed, Abd El-Nasser G. El Gendy, Sahar S. Abd El-Rahman, Abdelbaset M. Elgamal, Abdelsamed I. Elshamy
Summary: The essential oil from the shoots of Araucaria bidiwillii trees shows significant anti-inflammatory and antipyretic effects, indicating its potential therapeutic value against various inflammatory and fever-related conditions, likely due to its active constituents.
Article
Plant Sciences
Ellen Nayara Silva de Jesus, Mateus Silva Tavares, Pedro Anibal C. Barros, Daniele Carvalho Miller, Pedro Iuri C. da Silva, Jofre Jacob S. Freitas, Anderson B. de Lima, William N. Setzer, Joyce Kelly R. da Silva, Pablo Luis B. Figueiredo
Summary: This study evaluated the acute oral toxic, antinociceptive, and anti-inflammatory activities of Eugenia uniflora essential oil. The essential oil showed analgesic and anti-inflammatory effects without causing toxicity in animals.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Chemistry, Applied
Cicero R. B. dos Santos, Mariana G. V. Sampaio, Lilian C. S. Vandesmet, Bruno S. dos Santos, Saulo A. de Menezes, Benedito Y. M. Portela, Douglas W. R. Gomes, Maria T. S. Correia, Maria C. V. Gomez, Irwin de Alencar R. Menezes, Marcia V. da Silva
Summary: This study investigated the volatile components and activities of the essential oil obtained from the leaves of Eugenia stipitata McVaugh. The oil showed high selective activity against Leishmania braziliensis and good antibacterial activity. However, its free-radical scavenging activity was low. These findings suggest that the essential oil of Eugenia stipitata is a valuable source for the development of antibacterial and antiprotozoal drugs.
NATURAL PRODUCT RESEARCH
(2023)
Article
Chemistry, Applied
Eudecio Bonfim dos Santos Dias, Yanuzi Mara Vargas Camilo, Eli Regina Barboza de Souza, Pedro Henrique Ferri
Summary: This study analyzed the essential oils of Eugenia dysenterica fruits from seven populations and found that variations in oils were mainly explained by the predictors of population, operational chemical units, and foliar Mn2+. These factors accounted for 86.8% of the variation in oils, with foliar Mn2+ making the largest contribution.
NATURAL PRODUCT RESEARCH
(2023)
Article
Food Science & Technology
Nilesh Prakash Nirmal, Phatchada Chunhavacharatorn, Anandu Chandra Khanashyam, Li Li, Fahad Al-Asmari
Summary: The nano-emulsion of cinnamon bark oil (CBON) was formulated and investigated for stability and antimicrobial properties. The droplet size and PDI of the CBO were found to be influenced by HLB value, treatment time, and smix concentration. CBON was found to be more efficient in inhibiting and inactivating microorganisms than the crude CBO, with S. cerevisiae being the most sensitive followed by E. coli and S. aureus.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Agricultural Engineering
Caroline F. da Silva, Rafaela R. Petro, Rafael N. Almeida, Eduardo Cassel, Rubem M. F. Vargas
Summary: The study investigates the extraction and encapsulation of Hedychium coronarium essential oil, aiming to enhance its physicochemical stability and preserve its scent properties. The encapsulation process with polycaprolactone showed promising results in maintaining the stability of the essential oil and its release properties.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Plant Sciences
Md Sharif Reza, Md Jashimuddin, Jamiuddin Ahmed, Muhammad Abeer, Nura Ershad Naznin, Sarah Jafrin, Md Enamul Haque, Md Abdul Barek, A. F. M. Shahid Ud Daula
Summary: The investigational study demonstrated promising analgesic and antipyretic activities of A. indica, supporting its traditional uses.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Plant Sciences
Bruno Oliveira de Veras, Joao Ricardhis Saturnino de Oliveira, Vera Lucia de Menezes Lima, Daniela Maria do Amaral Ferraz Navarro, Julio Cesar Ribeiro de Oliveira Farias de Aguiar, Geovanna Maria de Medeiros Moura, Jose Wellinton da Silva, Caio Rodrigo Dias de Assis, Krystyna Gorlach-Lira, Priscilla Anne Castro de Assis, Jorge Irapuan de Souza Barbosa, Maria Rita Cabral Sales de Melo, Maria Betania Melo de Oliveira, Marcia Vanusa da Silva, Ana Catarina de Souza Lopes
Summary: This study investigated the chemical composition and various activities of the essential oil from Verbesina macrophylla, including antimicrobial, anti-inflammatory, and antipyretic properties. The essential oil showed low hemolytic activity on human red blood cells and demonstrated safety in acute toxicity testing in animals. The results suggest potential industrial value in developing drugs with natural antimicrobial, anti-inflammatory, and antipyretic effects from V. macrophylla.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Agricultural Engineering
Eleonora Spinozzi, Roman Pavela, Giulia Bonacucina, Diego R. Perinelli, Marco Cespi, Riccardo Petrelli, Loredana Cappellacci, Dennis Fiorini, Serena Scortichini, Stefania Garzoli, Cristina Angeloni, Michela Freschi, Silvana Hrelia, Luana Quassinti, Massimo Bramucci, Giulio Lupidi, Stefania Sut, Stefano Dall'Acqua, Giovanni Benelli, Angelo Canale, Ettore Drenaggi, Filippo Maggi
Summary: Acmella oleracea, also known as jambu, is a versatile plant with active ingredient spilanthol used in various industries. Microwave-assisted extraction can enhance the yield and content of spilanthol in the EO. The EO mainly consists of monoterpenes and sesquiterpenes, with spilanthol also present, showing significant larvicidal activity against Culex quinquefasciatus. The nanoemulsion of A. oleracea EO displays excellent physical stability and higher efficacy in reducing adult fertility compared to spilanthol, indicating potential for mosquito larvicide development. The safety of A. oleracea EO, NE, and spilanthol in mammalian cell assays suggests low cytotoxicity and protective effects against inflammation.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Plant Sciences
Chun Fai Wong, Cheuk Ka Poon, Tsz Wai Ng, Hok Him Pan, Eng Cheng Khaw, Ki Fong Tsang, Yan Wing Mui, Yuk Hong Lo, Mui Fung Hao, Chun Hay Ko
Summary: This study evaluated the anti-inflammatory and toxicology effects of H. cordata essential oil-containing formulation, H16 aerosol, in vivo. The study found that H16 aerosol had anti-inflammatory and antipyretic effects, and it was safe for use. This suggests that H16 aerosol could be a new herbal therapy and contribute to the modernization of herbal medicine.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Yixian Quah, Shi-Ruo Tong, Joanna Bojarska, Katrin Giller, Sheri-Ann Tan, Zyta Maria Ziora, Tuba Esatbeyoglu, Tsun-Thai Chai
Summary: In the past decade, researchers have shown increasing interest in exploring bioactive peptides derived from edible insects. These peptides have the potential to address human health issues and protect crops and livestock from pathogens. The diversity of bioactive peptides identified from edible insects suggests their potential in addressing various health problems such as inflammation, diabetes, and obesity. While most experiments have been conducted in vitro, evidence is emerging on the in vivo efficacy of some peptides.
Article
Chemistry, Multidisciplinary
Afia Shahid, Kashif Ur Rehman Khan, Huma Rao, Hanan Y. Aati, Asmaa E. Sherif, Duraiz Ahmed Khan, Abdul Basit, Muhammad Umair, Abdul Mueed, Tuba Esatbeyoglu, Sameh A. Korma
Summary: This study investigated the phytochemical composition, biological activities, and in silico molecular docking of the ethanolic extract of Zaleya pentandra, the only species of its genus found in the Cholistan desert, Pakistan. The extract showed high phenolic and flavonoid content and exhibited strong antioxidant, enzyme inhibition, antibacterial, and antiviral activities. In silico molecular docking revealed the interaction and binding affinity of the identified compounds with enzymes. These findings provide valuable insights into the potential anti-diabetic, neuroprotective, and skin-protective uses of Z. pentandra and can contribute to the discovery of bioactive compounds in the future.
APPLIED SCIENCES-BASEL
(2023)
Article
Food Science & Technology
Sherif M. Afifi, Eman M. Kabbash, Ralf G. Berger, Ulrich Krings, Tuba Esatbeyoglu
Summary: Differences in metabolites were investigated in seven authentic samples of Citrus sinensis peel and juices from Spain and Uruguay, as well as a concentrate from Brazil. Sixty-six metabolites belonging to various chemical groups were detected, including phenolic acids, coumarins, flavonoid glycosides, limonoids, terpenes, and fatty acids. Some flavonoids were found to be more abundant in the peel than in the juice, suggesting potential industrial and economic prospects. Multivariate data analyses showed that the differences among orange parts were more significant than the geographical source.
Editorial Material
Computer Science, Hardware & Architecture
Ahmed H. Madian, Mohamed Abdelghani Salem, Abdallah Kassem
ANALOG INTEGRATED CIRCUITS AND SIGNAL PROCESSING
(2023)
Review
Biochemistry & Molecular Biology
Anfal Alwan Al-Temimi, Aum-El-Bashar Al-Mossawi, Sawsan A. Al-Hilifi, Sameh A. Korma, Tuba Esatbeyoglu, Joao Miguel Rocha, Vipul Agarwal
Summary: Glutathione is a naturally occurring compound that plays a crucial role in cellular response to oxidative stress. The alteration in glutathione homeostasis can be used as a potential marker for human diseases. The determination and quantification of glutathione remain challenging, but understanding its bioprocessing can have implications for the food industry and human health.
Article
Chemistry, Analytical
Ahmed M. Abd-ElGawad, Ibrahim Saleh, Mohamed H. Abd El-Razek, Asmaa S. Abd Elkarim, Yasser A. El-Amier, Tarik A. Mohamed, Abd El-Nasser G. El Gendy, Sherif M. Afifi, Tuba Esatbeyoglu, Abdelsamed I. Elshamy
Summary: In this study, the essential oil (EO) from Araucaria heterophylla Salisb. resin was extracted using the microwave technique and chemically characterized via GC-MS analysis. The EO showed a significant antioxidant activity, with IC50 values of 142.42 and 118.03 mg L-1 for DPPH and ABTS, respectively. Moreover, it exhibited considerable phytotoxicity against the weeds Chenopodium murale and Sonchus oleraceus. These findings suggest that the EO of A. heterophylla resin could be a promising natural resource for weed management.
Article
Agricultural Engineering
Abdulwahab Alqahtani, Mohamed F. Abdelhameed, Randa Abdou, Ammar M. Ibrahim, Mohamed Dawoud, Saeed M. Alasmari, Mohamed A. El Raey, Hany G. Attia
Summary: Linalyl acetate in bitter orange leaf extract shows good anti-inflammatory and antipyretic effects, which can alleviate inflammation by improving antioxidant status and inhibiting the production of inflammatory mediators. Linalyl acetate also exhibits a significant fast onset anti-inflammatory effect.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Food Science & Technology
Gulay Ozkan, Manolya Eser Oner, Dilara Tas, Tuba Esatbeyoglu, Esra Capanoglu
Summary: This study investigated the effects of food processing techniques and in vitro gastrointestinal digestion on the phenolics of loquat products. The results showed that processing loquats into leather and jam can improve and protect the phenolic content of the fresh fruit, thereby increasing the nutritional value of the products.
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION
(2023)
Article
Microbiology
Adila Naseem, Saeed Akhtar, Tariq Ismail, Muhammad Qamar, Dur-e-shahwar Sattar, Wisha Saeed, Tuba Esatbeyoglu, Elena Bartkiene, Joao Miguel Rocha
Summary: This study investigates the effects of fermentation on the nutrient-delivering potential and antinutrients of spinach at different growth stages. The results show that fermentation significantly increases the protein and fiber content of spinach, while reducing total carbohydrate content. Furthermore, fermentation decreases the levels of alkaloids, oxalates, phytates, and glucosinolates in spinach. However, fermentation has no impact on the total phenolic content and antioxidant potential of spinach.
Article
Microbiology
Awais Khan, Muhammad Nadeem, Fahad Al-Asmari, Muhammad Imran, Saadia Ambreen, Muhammad Abdul Rahim, Sadaf Oranab, Tuba Esatbeyoglu, Elena Bartkiene, Joao Miguel Rocha
Summary: This study investigated the effect of Lactiplantibacillus plantarum on CLA production and sensory characteristics of cheddar cheese. The results showed that Lp. plantarum and safflower oil can increase the production of CLA in cheddar cheese without affecting its composition and sensory properties.
Article
Microbiology
Gamal M. Hamad, Mariam Gerges, Taha Mehany, Saleh M. Hussein, Michael Eskander, Rasha G. Tawfik, Yasser El-Halmouch, Alaa M. Mansour, Elsayed E. Hafez, Tuba Esatbeyoglu, Eman M. Elghazaly
Summary: This study evaluated the occurrence of Campylobacter jejuni in chicken meat and its control using three types of sorghum extracts. The results showed that C. jejuni was abundant in chicken meat, especially breast and thigh. The white sorghum (WS) extract displayed the highest antibacterial activity and antioxidant potential. The use of WS extract at different concentrations effectively reduced C. jejuni in inoculated chicken fillet samples and enhanced the sensory attributes of grilled chicken fillet.
Article
Biotechnology & Applied Microbiology
Khaled S. Nassar, Ibrahim Attia, Sameh A. Korma, Salam A. Ibrahim, Tuba Esatbeyoglu, Eman Saad Ragab
Summary: The objective of this study was to evaluate the nutritional value of dried Kishk-like products made with wheat, oat, and fenugreek mixed with cow's milk, camel's milk, and goat's milk. The results showed that these products have a long shelf life, making them a safe food option for infants, children, and elderly individuals requiring specialized care.
FERMENTATION-BASEL
(2023)
Review
Chemistry, Multidisciplinary
Aya A. Wafaey, Seham S. El-Hawary, Farid N. Kirollos, Mohamed F. Abdelhameed
Summary: Medicinal plants have been used since prehistoric times and Gliricidia sepium is one of the most important plants in pharmacognosy and medical fields. It contains bioactive compounds that have been extracted and used for various traditional applications, such as treating coughs and asthma. Over time, numerous medicinal uses have been discovered, including anti-inflammatory and antioxidant activities.
EGYPTIAN JOURNAL OF CHEMISTRY
(2023)
Review
Chemistry, Medicinal
Ahmed Zayed, Mohamed A. Salem, Walaa A. Negm, Shahira M. Ezzat
Summary: Fever is a complex process caused by infection and inflammation, which can have severe biological effects on the body. Anti-pyretic drugs are prescribed to reduce body temperature and protect the brain. Natural anti-pyretic drugs are in high demand, and this article discusses the pathways, models, and screening of anti-pyretic natural products. It could contribute to the development of safe and effective natural anti-pyretic medications.
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY
(2023)
Article
Chemistry, Multidisciplinary
Mohamed F. Abdelhameed, Ahmed M. Nagy, Sherif S. Mohamed
Summary: This study compares the impact of common food additives (MSG, ACK, BHA and BHT) on fetal development, and finds that these additives have a negative effect. Pregnant consumers are advised to avoid consuming food additives.
EGYPTIAN JOURNAL OF CHEMISTRY
(2023)