A novel visible light mediated radical cyclization of enol lactones: a concise method for fluorinated polycyclic lactone scaffolds

A novel visible light mediated radical cyclization of enol lactones with difluoroacyl arenes is presented. The reaction experienced a tandem radical cyclization and tolerated a wide range of substrates, resulting in fluorinated gamma-butyrolactones in good chemical yield and with excellent diastereoselectivity.