期刊
MICROPOROUS AND MESOPOROUS MATERIALS
卷 220, 期 -, 页码 148-154出版社
ELSEVIER
DOI: 10.1016/j.micromeso.2015.08.037
关键词
Metal-organic framework; Continuous flow microreactor; Nanoparticle; Drug delivery
类别
资金
- NSFC [21203032, 21471035]
- Shanghai Leading Academic Discipline Project [B108]
In this paper, UiO-66 nanoparticles have been facilely prepared in a continuous flow microreactor, in which the particle size can be tuned from hundreds to dozens of nanometers by controlling of the residence time. All the products have been completely characterized by FT-IR, PXRD, N-2 sorption, SEM and TEM. Furthermore, NH2-functionalized nano-UiO-66 particles have also been prepared and the drug delivery behavior for 5-fluorouracil (5-Fu) was studied in PBS solution. (c) 2015 Elsevier Inc. All rights reserved.
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