标题
NLRP3 Inflammasome as a Potential Therapeutic Target in Dry Eye Disease
作者
关键词
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出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 24, Issue 13, Pages 10866
出版商
MDPI AG
发表日期
2023-06-30
DOI
10.3390/ijms241310866
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A topical fluorometholone nanoformulation fabricated under aqueous condition for the treatment of dry eye
- (2022) Tian-zuo Wang et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Comparison of seven cyclosporine A formulations for dry eye disease: A systematic review and network meta-analysis
- (2022) Dongyang Gao et al. Frontiers in Pharmacology
- A combination of CMC and α-MSH inhibited ROS activated NLRP3 inflammasome in hyperosmolarity stressed HCECs and scopolamine-induced dry eye rats
- (2021) Ying Lv et al. Scientific Reports
- Blocking the inflammasome: A novel approach to treat uveitis
- (2021) Avik Shome et al. DRUG DISCOVERY TODAY
- The role of the inflammasomes in the pathogenesis of uveitis
- (2021) Qiuyun Xu et al. EXPERIMENTAL EYE RESEARCH
- Exosomes Derived From Mouse Adipose-derived Mesenchymal Stem Cells Alleviate BAC-induced Mouse Dry Eye Model Via Inhibiting NLRP3 Inflammasome
- (2021) Guifang Wang et al. OPHTHALMIC RESEARCH
- Impact of Low Humidity on Damage Associated Molecular Patterns at the Ocular Surface during Dry Eye Disease
- (2021) Alyce Alven et al. OPTOMETRY AND VISION SCIENCE
- Calcitriol Alleviates Hyperosmotic Stress-Induced Corneal Epithelial Cell Damage via Inhibiting the NLRP3–ASC–Caspase-1–GSDMD Pyroptosis Pathway in Dry Eye Disease
- (2021) Jing Zhang et al. Journal of Inflammation Research
- Associations Between Systemic Omega-3 Fatty Acid Levels With Moderate-to-Severe Dry Eye Disease Signs and Symptoms at Baseline in the Dry Eye Assessment and Management Study
- (2020) Eric J. Kuklinski et al. Eye & Contact Lens-Science and Clinical Practice
- The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-κB/NLRP3 signaling
- (2020) Fang-ming Yang et al. ACTA PHARMACOLOGICA SINICA
- NLRP12- and NLRC4-mediated corneal epithelial pyroptosis is driven by GSDMD cleavage accompanied by IL-33 processing in dry eye
- (2020) Hui Chen et al. Ocular Surface
- Safety of KPI-121 Ophthalmic Suspension 0.25% in Patients With Dry Eye Disease
- (2020) Michael Korenfeld et al. CORNEA
- In Vivo Anti-Inflammation Potential of Aster koraiensis Extract for Dry Eye Syndrome by the Protection of Ocular Surface
- (2020) Sung-Chul Hong et al. Nutrients
- hADSCs derived extracellular vesicles inhibit NLRP3inflammasome activation and dry eye
- (2020) Chaoqun Yu et al. Scientific Reports
- Defining Dry Eye from a Clinical Perspective
- (2020) Kazuo Tsubota et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Lifitegrast Ophthalmic Solution 5.0% for Treatment of Dry Eye Disease: Overview of Clinical Trial Program
- (2019) Clara C Chan et al. JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
- Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury
- (2019) Alexey Pronin et al. Frontiers in Molecular Neuroscience
- A New Perspective on Dry Eye Classification
- (2019) Kazuo Tsubota et al. Eye & Contact Lens-Science and Clinical Practice
- The Dry Eye Assessment and Management (DREAM) extension study – A randomized clinical trial of withdrawal of supplementation with omega-3 fatty acid in patients with dry eye disease
- (2019) Munira Hussain et al. Ocular Surface
- Polydatin Inhibits NLRP3 Inflammasome in Dry Eye Disease by Attenuating Oxidative Stress and Inhibiting the NF-κB Pathway
- (2019) Bongkyun Park et al. Nutrients
- n−3 Fatty Acid Supplementation for the Treatment of Dry Eye Disease
- (2018) NEW ENGLAND JOURNAL OF MEDICINE
- Connexin43 hemichannel block protects against the development of diabetic retinopathy signs in a mouse model of the disease
- (2018) Odunayo O. Mugisho et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Conjunctival Inflammatory Gene Expression Profiling in Dry Eye Disease: Correlations With HLA-DRA and HLA-DRB1
- (2018) Karima Kessal et al. Frontiers in Immunology
- Once-Daily Cyclosporine-A-MiDROPS for Treatment of Dry Eye Disease
- (2018) Terry G. Coursey et al. Translational Vision Science & Technology
- Calcitriol inhibits ROS-NLRP3-IL-1β signaling axis via activation of Nrf2-antioxidant signaling in hyperosmotic stress stimulated human corneal epithelial cells
- (2018) Yiqin Dai et al. Redox Biology
- Corneal regeneration by conditioned medium of human uterine cervical stem cells is mediated by TIMP-1 and TIMP-2
- (2018) Juan Sendon-Lago et al. EXPERIMENTAL EYE RESEARCH
- Immunohistochemical Characterization of Connexin43 Expression in a Mouse Model of Diabetic Retinopathy and in Human Donor Retinas
- (2017) Odunayo Mugisho et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye
- (2017) Wei Chi et al. JOURNAL OF AUTOIMMUNITY
- LFA-1/ICAM-1 Interaction as a Therapeutic Target in Dry Eye Disease
- (2017) Stephen C. Pflugfelder et al. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
- TFOS DEWS II pathophysiology report
- (2017) Anthony J. Bron et al. Ocular Surface
- TFOS DEWS II Management and Therapy Report
- (2017) Lyndon Jones et al. Ocular Surface
- TFOS DEWS II Definition and Classification Report
- (2017) Jennifer P. Craig et al. Ocular Surface
- A comparison of the self-reported dry eye practices of New Zealand optometrists and ophthalmologists
- (2017) Ally L. Xue et al. OPHTHALMIC AND PHYSIOLOGICAL OPTICS
- Lifitegrast for the Treatment of Dry Eye Disease
- (2017) Edward J. Holland et al. OPHTHALMOLOGY
- Revisiting the vicious circle of dry eye disease: a focus on the pathophysiology of meibomian gland dysfunction
- (2016) Christophe Baudouin et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Safety of Lifitegrast Ophthalmic Solution 5.0% in Patients With Dry Eye Disease
- (2016) Eric D. Donnenfeld et al. CORNEA
- Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
- (2016) Xing Liu et al. NATURE
- Topical Fluorometholone Protects the Ocular Surface of Dry Eye Patients from Desiccating Stress
- (2016) José Pinto-Fraga et al. OPHTHALMOLOGY
- On the prescribing of oral doxycycline or minocycline by UK optometrists as part of management of chronic Meibomian Gland Dysfunction (MGD)
- (2016) Michael J. Doughty Contact Lens & Anterior Eye
- Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
- (2015) Wan-ting He et al. CELL RESEARCH
- Reactive oxygen species activated NLRP3 inflammasomes initiate inflammation in hyperosmolarity stressed human corneal epithelial cells and environment-induced dry eye patients
- (2015) Qinxiang Zheng et al. EXPERIMENTAL EYE RESEARCH
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Lifitegrast Ophthalmic Solution 5.0% versus Placebo for Treatment of Dry Eye Disease
- (2015) Joseph Tauber et al. OPHTHALMOLOGY
- Upregulation of NLRP3 Inflammasome in the Tears and Ocular Surface of Dry Eye Patients
- (2015) Liangliang Niu et al. PLoS One
- Treatment of Sjögren's syndrome dry eye using 0.03% tacrolimus eye drop: Prospective double-blind randomized study
- (2015) Bernardo Kaplan Moscovici et al. Contact Lens & Anterior Eye
- NLRP3 inflammasome and its inhibitors: a review
- (2015) Bo-Zong Shao et al. Frontiers in Pharmacology
- Oral azithromycin versus doxycycline in meibomian gland dysfunction: a randomised double-masked open-label clinical trial
- (2014) Mohsen Bahmani Kashkouli et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Donor and host B cell-derived IL-10 contributes to suppression of graft-versus-host disease
- (2014) Michael Weber et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye
- (2014) Qinxiang Zheng et al. EXPERIMENTAL EYE RESEARCH
- The Core Mechanism of Dry Eye Disease Is Inflammation
- (2014) Yi Wei et al. Eye & Contact Lens-Science and Clinical Practice
- The NLRP3 inflammasome: role in airway inflammation
- (2013) H. Im et al. CLINICAL AND EXPERIMENTAL ALLERGY
- The Application of Autologous Serum Eye Drops in Severe Dry Eye Patients; Subjective and Objective Parameters Before and After Treatment
- (2013) Katerina Jirsova et al. CURRENT EYE RESEARCH
- HLA-DR expression as a biomarker of inflammation for multicenter clinical trials of ocular surface disease
- (2013) Seth P. Epstein et al. EXPERIMENTAL EYE RESEARCH
- Role of Hyperosmolarity in the Pathogenesis and Management of Dry Eye Disease: Proceedings of the OCEAN Group Meeting
- (2013) Christophe Baudouin et al. Ocular Surface
- Short-term Consumption of Oral Omega-3 and Dry Eye Syndrome
- (2013) Haleh Kangari et al. OPHTHALMOLOGY
- Lifitegrast Ophthalmic Solution 5.0% for Treatment of Dry Eye Disease
- (2013) John D. Sheppard et al. OPHTHALMOLOGY
- Quantification of Conjunctival TNF-α in Aqueous-Deficient Dry Eye
- (2013) Barbary E. Caffery et al. OPTOMETRY AND VISION SCIENCE
- Minocycline Controls Clinical Outcomes and Inflammatory Cytokines in Moderate and Severe Meibomian Gland Dysfunction
- (2012) Hun Lee et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Dry Eye Disease
- (2012) William Stevenson ARCHIVES OF OPHTHALMOLOGY
- Azithromycin 1.5% ophthalmic solution: efficacy and treatment modalities in chronic blepharitis
- (2012) Ali Fadlallah et al. ARQUIVOS BRASILEIROS DE OFTALMOLOGIA
- The Effect of Topical Pranoprofen 0.1% on the Clinical Evaluation and Conjunctival HLA-DR Expression in Dry Eyes
- (2012) Xiaowei Liu et al. CORNEA
- A Randomized Double-Masked Study of 0.05% Cyclosporine Ophthalmic Emulsion in the Treatment of Meibomian Gland Dysfunction
- (2012) Pinnita Prabhasawat et al. CORNEA
- Randomized Double-Blind Clinical Trial of Autologous Serum Versus Artificial Tears in Dry Eye Syndrome
- (2012) Cristhian A. Urzua et al. CURRENT EYE RESEARCH
- Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes
- (2012) Hye-Mi Lee et al. DIABETES
- Immunotherapeutic applications of IL-18
- (2012) Hiroko Tsutsui et al. Immunotherapy
- NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
- (2012) Sarah L Doyle et al. NATURE MEDICINE
- Essential Fatty Acids in the Treatment of Dry Eye
- (2012) Elana S. Rosenberg et al. Ocular Surface
- Tofacitinib (CP-690,550), a Janus Kinase Inhibitor for Dry Eye Disease
- (2012) Shiao Hui (Melissa) Liew et al. OPHTHALMOLOGY
- Immunomodulatory Effect of the Topical Ophthalmic Janus Kinase Inhibitor Tofacitinib (CP-690,550) in Patients with Dry Eye Disease
- (2012) Jing-Feng Huang et al. OPHTHALMOLOGY
- Ocular surface immunity: Homeostatic mechanisms and their disruption in dry eye disease
- (2012) Stefano Barabino et al. PROGRESS IN RETINAL AND EYE RESEARCH
- A multicentre, double-masked, randomized, controlled trial assessing the effect of oral supplementation of omega-3 and omega-6 fatty acids on a conjunctival inflammatory marker in dry eye patients
- (2011) Françoise Brignole-Baudouin et al. ACTA OPHTHALMOLOGICA
- Interferon-γ-secreting NK cells promote induction of dry eye disease
- (2011) Yihe Chen et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Disruption of TGF-β Signaling Improves Ocular Surface Epithelial Disease in Experimental Autoimmune Keratoconjunctivitis Sicca
- (2011) Cintia S. De Paiva et al. PLoS One
- Regulation of Expression of Interleukin-6
- (2010) ANURADHA RAY et al. Annals of the New York Academy of Sciences
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Multicenter Open-Label Study Evaluating the Efficacy of Azithromycin Ophthalmic Solution 1% on the Signs and Symptoms of Subjects With Blepharitis
- (2010) Reza M Haque et al. CORNEA
- Regulation of inflammasome activity
- (2010) Greta Guarda et al. IMMUNOLOGY
- Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease
- (2010) Reiko M. Onishi et al. IMMUNOLOGY
- Tripartite-Motif Protein 30 Negatively Regulates NLRP3 Inflammasome Activation by Modulating Reactive Oxygen Species Production
- (2010) Y. Hu et al. JOURNAL OF IMMUNOLOGY
- Autoimmunity at the ocular surface: pathogenesis and regulation
- (2010) M E Stern et al. Mucosal Immunology
- Dry Eye Disease as an Inflammatory Disorder
- (2010) Margarita Calonge et al. OCULAR IMMUNOLOGY AND INFLAMMATION
- Interleukin-1 Receptor-1-deficient Mice Show Attenuated Production of Ocular Surface Inflammatory Cytokines in Experimental Dry Eye
- (2009) Srihari Narayanan et al. CORNEA
- Analysis of Inflammatory Cytokines in the Tears of Dry Eye Patients
- (2009) Morgan L Massingale et al. CORNEA
- Janus kinases in immune cell signaling
- (2009) Kamran Ghoreschi et al. IMMUNOLOGICAL REVIEWS
- Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
- (2009) F. G. Bauernfeind et al. JOURNAL OF IMMUNOLOGY
- IL-17 disrupts corneal barrier following desiccating stress
- (2009) C S De Paiva et al. Mucosal Immunology
- Age-related T-cell cytokine profile parallels corneal disease severity in Sjogren's syndrome-like keratoconjunctivitis sicca in CD25KO mice
- (2009) C. S. De Paiva et al. RHEUMATOLOGY
- The NLRP3 inflammasome: A sensor of immune danger signals
- (2009) Suzanne L. Cassel et al. SEMINARS IN IMMUNOLOGY
- Tear Cytokine Profiles in Dysfunctional Tear Syndrome
- (2008) Helene Lam et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Autologous Serum Eye Drops for the Treatment of Dry Eye Diseases
- (2008) Takashi Kojima et al. CORNEA
- The phenotype of human Th17 cells and their precursors, the cytokines that mediate their differentiation and the role of Th17 cells in inflammation
- (2008) F. Annunziato et al. INTERNATIONAL IMMUNOLOGY
- Inflammatory Markers in the Tears of Patients with Ocular Surface Disease
- (2008) Arantxa Acera et al. OPHTHALMIC RESEARCH
- How corticosteroids control inflammation: Quintiles Prize Lecture 2005
- (2006) Peter J Barnes BRITISH JOURNAL OF PHARMACOLOGY
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