Article
Chemistry, Multidisciplinary
Romina Alarcon, Mariana Walter, Maritza Paez, Manuel Ignacio Azocar
Summary: In this study, the stability and antibacterial activity of silver nanoparticles (AgNPs) coated with different stabilizers were investigated. The AgNPs showed differences in stability and size change depending on the coating agent used. The stabilizer may function as a growth controller of the nanoparticles, affecting their biological properties. The protective or stabilizing agents also played a role in the antibacterial capacity and stability of AgNPs over time.
Review
Pharmacology & Pharmacy
Ilker S. Bayer
Summary: Polysaccharides are complex molecules with exceptional properties and can be chemically modified. They have increased application in drug encapsulation and release in nanoscale synthesis due to their biocompatibility and biodegradability. This review focuses on studying sustained drug release from nanoscale polysaccharides, particularly drug release kinetics and mathematical modeling. It highlights the importance of modeling in predicting the behavior of specific polysaccharide matrices and reducing experimental trial and error.
Article
Materials Science, Multidisciplinary
Sathish Kumar Karuppannan, Raghavendra Ramalingam, Mohamed S. B. Khalith, Shazia Anjum Musthafa, Mohammed Junaid Hussain Dowlath, Ganesh Munuswamy-Ramanujam, Kantha Deivi Arunachalam
Summary: The study focuses on the green synthesis and characterization of copper oxide nanoparticles infused Polycaprolactone/Gelatin electro-spun nanofibers, which show good antimicrobial properties and promote wound healing. The fabricated nanofibers have good performance and can be effectively used in wound care management.
Article
Chemistry, Physical
K. Chandramouli, B. Suryanarayana, T. Anil Babu, Vemuri Raghavendra, D. Parajuli, N. Murali, Venkaiah Malapati, Tulu Wegayehu Mammo, P. S. Shanmukhi, Umesh Reddy Gudla
Summary: The structure, particle size, and antibiotic nature of synthesized ZnO nanoparticles were studied using XRD, TEM, and FTIR, revealing spherical particles with a single wurtzite hexagonal crystal structure. The correlation between defect and antibiotic properties of ZnO was identified.
SURFACES AND INTERFACES
(2021)
Article
Polymer Science
Valeria Allizond, Giuliana Banche, Matteo Salvoni, Mery Malandrino, Claudio Cecone, Anna Maria Cuffini, Pierangiola Bracco
Summary: Nanofibers, prepared using a simple electrospinning method, containing silver nanoparticles were found to have antimicrobial activity against Staphylococcus epidermidis and Escherichia coli. The release of silver nanoparticles was more efficient in PLA/PEO nanofibers compared to PLA nanofibers. These electrospun mats show potential for biomedical applications, especially in wound dressing to prevent infections.
Article
Biochemistry & Molecular Biology
Md Kaiser Haider, Azeem Ullah, Muhammad Nauman Sarwar, Yusuke Saito, Lei Sun, Soyoung Park, Ick Soo Kim
Summary: The study demonstrates the synthesis of CuO nanoparticles on electrospun cellulose nanofibers using alkali lignin as a reducing agent, showing potential as wound dressing material with excellent antibacterial efficacy and cell compatibility.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Nan-Fu Chen, Yu-Hsiang Liao, Pei-Ying Lin, Wu-Fu Chen, Zhi-Hong Wen, Shuchen Hsieh
Summary: In this study, CuO nanoparticles were synthesized via hydrothermal synthesis and then modified with different polymers to optimize bacteriostatic effects. Among them, PDA-modified CuO NPs showed excellent antibacterial activity with a bacteriostatic rate of 85.8%. Their superior performance can be attributed to their smaller size, surface charge, and favorable van der Waals interactions at pH 7.4, which increased their affinity for the lipopolysaccharide-containing outer membrane of E. coli.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Polymer Science
Muhammad Nauman Sarwar, Azeem Ullah, Md. Kaiser Haider, Nadir Hussain, Sana Ullah, Motahira Hashmi, Muhammad Qamar Khan, Ick Soo Kim
Summary: Adding DLF to PAN nanofibers increased fiber diameter and improved antibacterial properties. The nanofibers showed controlled drug release and good biocompatibility with human cells. Cell adhesion was stronger than material adhesion, making it suitable for wound care without causing disruption.
Article
Engineering, Environmental
Ammar Tarar, Ching-An Peng
Summary: In this study, silver nanoparticles with enhanced antibacterial activity were synthesized using sinigrin as both reducing and capping agent. The sinigrin-capped silver nanoparticles exhibited increased zone of inhibition against E. coli and prolonged inhibitory effect on bacterial growth.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Agricultural Engineering
Jiansong Chen, Liangliang An, Jin Ho Bae, Ji Won Heo, Song Yi Han, Yong Sik Kim
Summary: In this study, aminated lignin-silver complex was prepared as an effective antibacterial agent using kraft lignin. The complex showed antibacterial activity against various bacteria, making it a potential green alternative to silver nanoparticles.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Pharmacology & Pharmacy
Diana Elena Ciolacu, Raluca Nicu, Dana Mihaela Suflet, Daniela Rusu, Raluca Nicoleta Darie-Nita, Natalia Simionescu, Georgeta Cazacu, Florin Ciolacu
Summary: Considering the complex process of wound healing, an ideal wound dressing should possess multiple functionalities, including biocompatibility, biodegradability, moisture retention, antibacterial properties, wound protection, and wound healing promotion. In this study, a multifunctional hydrogel was designed using cellulose and chemically modified lignin, showing promising structural and morphological characteristics. The results demonstrate that the hydrogel has improved drug encapsulation and release, antibacterial properties, and mucoadhesion compared to cellulose-based hydrogels.
Article
Materials Science, Multidisciplinary
Justin D. Hochberg, David M. Wirth, Giovanni Spiaggia, Pooja Shah, Barbara Rothen-Rutishauser, Alke Petri-Fink, Jonathan K. Pokorski
Summary: Polymeric nanofiber scaffolds are widely used for various applications, and a recent study developed a method to fabricate antibacterial nanofiber mats using melt coextrusion and photochemical modification. The resulting mats showed superior antimicrobial activity against both Gram-positive and Gram-negative bacteria while also being biocompatible. This work provides a scalable method for fabricating advanced, functional nonwoven mats for potential use as advanced bandages.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Materials Science, Paper & Wood
Yifan Liu, Beiqiu Chen, Yuancai Lv, Xiaoxia Ye, Chunxiang Lin, Minghua Liu
Summary: This study prepared LCNFs with lignin content ranging from 4.69% to 17.53% by adjusting the concentration of p-TsOH and hydrolysis temperature. It was found that the physical and chemical properties of LCNFs were significantly affected by the lignin content, with an increase leading to higher diameters and water contact angles, and lower crystallinity. Furthermore, by-product lignin nanoparticles (LNPs) with an average diameter of 50-500 nm were generated, enhancing the resource utilization value of SBP.
Article
Chemistry, Physical
Wioletta Florkiewicz, Klaudia Pluta, Dagmara Malina, Karolina Rudnicka, Anna Zywicka, Martin Duarte Guigou, Bozena Tyliszczak, Agnieszka Sobczak-Kupiec
Summary: This study demonstrated the plant-mediated preparation of silver nanoparticles using aqueous extracts and infusion of Cistus incanus leaves, which exhibited high antioxidant capacity. The nanoparticles had an average size of around 70 nm and a spherical structure with a face-centred cubic phase composition. Cytotoxicity tests suggested that the nanoparticles should be utilized at a concentration of 16 ppm, and minimum inhibitory concentrations for Staphylococcus aureus and Staphylococcus epidermidis were determined.
Review
Biochemistry & Molecular Biology
Aown Abbas, Zheng Wang, Yiru Zhang, Pai Peng, Diao She
Summary: This review evaluates the manufacturing processes of various types of controlled-release fertilizers (CRFs) based on lignin. The coated, chemically modified and chelated CRFs as well as lignin hydrogel-based CRFs are systematically summarized. The general mechanism for controlled release of lignin-based CRFs is discussed, and three common evaluation criteria of lignin-based CRFs efficiency are proposed. Overall, the use of lignin-based CRFs has the potential to greatly enhance resource efficiency and environmental protection.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)