Structure-based discovery of an immunomodulatory inhibitor of TLR1–TLR2 heterodimerization from a natural product-like database

Virtual screening and optimization of Type II inhibitors of JAK2 from a natural product library

(2014) Dik-Lung Ma et al.   CHEMICAL COMMUNICATIONS

Toll-Like Receptor 2-Mediated Innate Immune Responses against Junín Virus in Mice Lead to Antiviral Adaptive Immune Responses during Systemic Infection and Do Not Affect Viral Replication in the Brain

(2014) Christian D. Cuevas et al.   JOURNAL OF VIROLOGY

Natural product and natural product derived drugs in clinical trials

(2014) Mark S. Butler et al.   NATURAL PRODUCT REPORTS

Discovery of a Natural Product-Like iNOS Inhibitor by Molecular Docking with Potential Neuroprotective Effects In Vivo

(2014) Hai-Jing Zhong et al.   PLoS One

Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening

(2014) L-J Liu et al.   Cell Death & Disease

Toll-like receptor stimulation increases phagocytosis of Cryptococcus neoformans by microglial cells

(2013) Sandra Redlich et al.   Journal of Neuroinflammation

Discovery of Small-Molecule Inhibitors of the TLR1/TLR2 Complex

(2012) Kui Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A natural product-like inhibitor of NEDD8-activating enzyme

(2011) Chung-Hang Leung et al.   CHEMICAL COMMUNICATIONS

Deregulated inflammasome signaling in disease

(2011) Mohamed Lamkanfi et al.   IMMUNOLOGICAL REVIEWS

Molecular docking for virtual screening of natural product databases

(2011) Dik-Lung Ma et al.   Chemical Science

Discovery of a novel TLR2 signaling inhibitor with anti-viral activity

(2010) Shenghua Zhou et al.   ANTIVIRAL RESEARCH

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

The Staphylococcus aureus Lipoprotein SitC Colocalizes with Toll-Like Receptor 2 (TLR2) in Murine Keratinocytes and Elicits Intracellular TLR2 Accumulation

(2010) P. Muller et al.   INFECTION AND IMMUNITY

Targeting Toll-like receptors: emerging therapeutics?

(2010) Elizabeth J. Hennessy et al.   NATURE REVIEWS DRUG DISCOVERY

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

The Triacylated ATP Binding Cluster Transporter Substrate-binding Lipoprotein ofStaphylococcus aureusFunctions as a Native Ligand for Toll-like Receptor 2

(2009) Kenji Kurokawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

Toll-Like Receptor Prestimulation Increases Phagocytosis of Escherichia coli DH5  and Escherichia coli K1 Strains by Murine Microglial Cells

(2008) S. Ribes et al.   INFECTION AND IMMUNITY