Article
Nanoscience & Nanotechnology
Vasyl Chumachenko, Pavlo Virych, Guochao Nie, Petro Virych, Oleg Yeshchenko, Pavlo Khort, Anton Tkachenko, Volodymyr Prokopiuk, Nataliia Lukianova, Taras Zadvornyi, Michel Rawiso, Liyao Ding, Nataliya Kutsevol
Summary: Cancer chemotherapy is challenged by high toxicity and drug resistance. Using low toxic nanocarriers in combination with anticancer agents can enhance therapy effectiveness. Modern advances in nanotechnology facilitate the creation of materials with desired properties.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2023)
Article
Biophysics
Ali Mahmoudi, Prashant Kesharwani, Muhammed Majeed, Yong Teng, Amirhossein Sahebkar
Summary: Curcumin is a natural compound with promising therapeutic benefits, but it suffers from low solubility and bioavailability. Incorporating curcumin into gold nanoparticles can improve its properties and enhance its anticancer and antioxidant capacities. Additionally, the combination of nanogold and curcumin can be utilized in various therapeutic methods.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Alexandra D. Voloshina, Elina E. Mansurova, Leysan R. Bakhtiozina, Marina M. Shulaeva, Irek R. Nizameev, Anna P. Lyubina, Syumbelya K. Amerhanova, Marsil K. Kadirov, Albina Y. Ziganshina, Vyacheslav E. Semenov, Igor S. Antipin
Summary: This study presents a redox-sensitive nanocarrier for delivering anticancer drugs, which can enhance drug penetration into cells and demonstrate selective cytotoxicity in specific cell types.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Nanoscience & Nanotechnology
Moustafa T. Mabrouk, Huijuan Zhang, Asmaa A. Zidan, Hailey Kilian, Wei-Chiao Huang, Dushyant Jahagirdar, Joaquin Ortega, Jun Xia, Jonathan F. Lovell
Summary: A protein-based nanocarrier system utilizing histone and genipin can effectively deliver hydrophobic cargos through the gastrointestinal tract, demonstrating positive zeta potential and mucoadhesive properties. Cross-linking histone nanoparticles with genipin enhances stability and enables successful delivery of therapeutic compounds such as curcumin, significantly alleviating disease symptoms in a murine colitis model.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Medicine, Research & Experimental
Meihua Luo, Yuchen Li, Bo Peng, Jacinta White, Ermei Makila, Wing Yin Tong, Chung Hang Jonathan Choi, Bryan Day, Nicolas H. Voelcker
Summary: The clinical treatment of glioblastoma (GBM) is challenging due to the blood-brain barrier, chemotherapeutic resistance, and aggressive tumor metastasis. In this study, researchers developed porous silicon nanoparticles (pSiNPs) modified with antisense oligonucleotide (AON) for targeted gene and drug delivery in GBM treatment. These AON-modified pSiNPs (AON@pSiNPs) had selective internalization by GBM cells and human cerebral microvascular endothelial cells expressing scavenger receptors. The results showed that AON@pSiNPs could cross the blood-brain barrier, knock down the key driver of GBM invasion, and inhibit GBM cell migration, making them a potential strategy for clinical treatment of GBM and targeted drug and gene delivery.
MOLECULAR PHARMACEUTICS
(2023)
Review
Biotechnology & Applied Microbiology
Calina Ciont, Amalia Mesaros, Oana Lelia Pop, Dan Cristian Vodnar
Summary: This study aims to investigate the interaction between iron oxide nanoparticles (IONPs) and probiotic cells and their impact on iron absorption, bioavailability, and microbiota variation. Through literature research and synthesis, the authors utilized a rigorous search methodology and collected 122 relevant research articles. The results showed that probiotics carrying IONPs had better treatment efficacy compared to conventional methods.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Article
Medicine, Research & Experimental
Xiaomo Li, Sijia Yi, Debora B. Scariot, Santiago J. Martinez, Ben A. Falk, Cheryl L. Olson, Patricia S. Romano, Evan A. Scott, David M. Engman
Summary: The encapsulation of benznidazole within polymeric vesicles enhances intracellular delivery and reduces parasitemia and tissue parasitosis in a mouse model of Trypanosoma cruzi infection, demonstrating the potential for improved treatment of Chagas disease.
Article
Chemistry, Physical
Dong Wang, Zhihao Fan, Haofeng Min, Xinhao Wang, Hui Li, Guangcheng Wei, Jiqian Wang
Summary: NIR etchable nanoparticles were prepared by utilizing NIR-triggered degradation of ASBBCM to release functional YSV peptides. The release rate was closely related to the degree of photo-etching. In vitro and in vivo experiments demonstrated the excellent effectiveness of these photo-etchable nanoparticles in directed release.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Physical
Aritra Kumar Dan, Bari Aamna, Soumik De, Miguel Pereira-Silva, Raghaba Sahu, Ana Claudia Paiva-Santos, Sagarika Parida
Summary: Sericin nanoparticles have emerged as a promising drug delivery vector in cancer treatment, offering enhanced efficacy, stability, and targeted delivery of chemotherapeutic drugs. This review provides a comprehensive summary of the current research status and synthesis techniques of sericin nanoparticles, highlighting their potential in cancer mitigation.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Multidisciplinary
Adriana Zelenakova, Jaroslava Szucsova, Lubos Nagy, Vladimir Girman, Vladimir Zelenak, Veronika Huntosova
Summary: In this study, a drug delivery composite (DDC) consisting of ordered mesoporous silica, iron oxide magnetic nanoparticles (Fe2O3), and the drug naproxen (Napro) was prepared. The results reveal the suppression of the Brownian relaxation process and indicate the potential application of the composite as a drug nanocarrier for magnetic-targeted drug delivery.
Article
Multidisciplinary Sciences
Nishtha Chaurawal, Charu Misra, Harshita Abul Barkat, Reena Jatyan, Deepak Chitkara, Md Abul Barkat, Teenu Sharma, Bhupinder Singh, Kaisar Raza
Summary: This study encapsulated sorafenib tosylate (SFB) into a biocompatible carrier, improving its bioavailability by using a microemulsion formulation. The results showed that the sorafenib-loaded microemulsion had a stronger inhibitory effect on tumor cells compared to the original SFB, and the drug release was controlled.
SCIENTIFIC REPORTS
(2022)
Article
Biophysics
Rinki Verma, Virendra Singh, Biplob Koch, Manoj Kumar
Summary: In this study, Methotrexate-loaded chitosan nanoparticles (Meth-Cs-NPs) were formulated through ionic-gelation method. The nanoparticles exhibited significant efficacy for chemically induced breast cancer treatment and showed biocompatibility. Additionally, the nanoparticles demonstrated improved pharmacokinetics and anti-tumor efficacy compared to free Methotrexate, indicating their potential as a viable breast cancer treatment modality.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Materials Science, Multidisciplinary
Archana Sumohan Pillai, Varnitha Manikantan, Aleyamma Alexander, Govindaraj Sri Varalakshmi, Bose Allben Akash, Israel V. M. V. Enoch
Summary: In this paper, NIR-II radiation-absorbing and magnetically-responsive CuFe2S3 nanoparticles are investigated as drug delivery agents for enhanced chemotherapeutic efficacy. The loaded nanoparticles show excellent drug adsorption and are tested for anticancer potential against breast cancer cell lines.
MATERIALS TODAY COMMUNICATIONS
(2022)
Review
Chemistry, Physical
Arezoo Sodagar Taleghani, Ali Taghvaie Nakhjiri, Mohammad Javad Khakzad, Seyed Mahdi Rezayat, Pedram Ebrahimnejad, Amir Heydarinasab, Azim Akbarzadeh, Azam Marjani
Summary: In recent decades, significant progress has been made in cancer treatment, but finding more effective therapies is crucial. The application of drug delivery nanovehicles, particularly mesoporous silica nanoparticles (MSNPs), shows promise in reducing side effects. MSNPs possess excellent characteristics that make them suitable for targeted and stimuli responsive drug delivery in cancer treatment.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Biophysics
Guangming Gong, Wenhui Qian, Luzhong Zhang, Jia Jia, Jinbing Xie, Qing Zhu, Wenya Liu, Pin Tu, Ming Gao, Liang Zhang, Haiqing Tang, Hua Su, Kaifeng Wei, Changshen Zhou, Kai Kai Wang, Qinqin Pan
Summary: To improve the solubility and targeting efficiency of curcumin, transferrin-curcumin nanoparticles were successfully fabricated, which showed lower toxicity and better targeting ability.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Chemistry, Inorganic & Nuclear
Anjum Afrooze, Dadamiah P. M. D. Shaik
Summary: This study presents a solution combustion approach to produce marigold Co3O4 nanoparticles as potential electrode material for supercapacitors. The effect of vacuum annealing on the microstructural and electrochemical properties is explored, and the prepared nanoparticles exhibit high specific capacitance and electrochemical stability.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
A. Atta, Nuha Al-Harbi, B. M. Alotaibi, M. A. M. Uosif, E. Abdeltwab
Summary: In this study, PVA/NaI films were prepared by doping polyvinyl alcohol with sodium iodide. The films were then irradiated with argon ions at different fluence levels. Various characterization techniques were used to study the structural and electrical changes in the films. The results show that the dielectric behavior of the treated PVA/NaI films was significantly modified, making them more suitable for various devices.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Xingang Wang, Chao Ma, Fubing Zou, Hai Hu, Jiayu Li, Hongyun Luo
Summary: By hybridizing TiO2 photocatalyst with CaCO3 as the wall material and using linseed oil as the core material, self-cleaning and self-repairing microcapsules were produced using in-situ precipitation. The microcapsules were evaluated for their morphology, chemical composition, thermal stability, and self-cleaning and self-repairing properties. Results showed that the microcapsules had a rough and spherical surface, along with excellent thermal stability and repeatability. Increasing the dosage of microcapsules significantly increased the degradation rate of methylene blue, while the self-repairing effect of micro-cracks became more evident. The optimal microcapsule dosage was found to be 7.0 wt%.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Review
Chemistry, Inorganic & Nuclear
Muhammad Farooque Lanjwani, Mustafa Tuzen, Muhammad Yar Khuhawar, Tawfik A. Saleh
Summary: The development of the textile industry has raised concerns due to the contamination of drinking water by organic dyes, which pose a carcinogenic risk to humans. Nanomaterials, particularly semiconductors, have been utilized for photocatalytic degradation of dye pollutants. Various parameters, such as catalyst dosage, irradiation time, light sources, initial dye concentration, temperature, and pH, play significant roles in the degradation process. Different generations of photocatalytic nanomaterials, including single metal nanoparticles, binary and ternary metal oxides, as well as inert solid substrates with photocatalysts, have been employed for dye degradation.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
V. Ramasamy, E. Thenpandiyan, G. Suresh, T. Sathishpriya, Suresh Sagadevan
Summary: The nano CaCO3 and Eu3+ doped CaCO3/PEG nanocomposites were prepared through the biomimetic method. The prepared products were characterized and the electrochemical performance was evaluated. The results showed that the Eu3+ doped CaCO3/PEG nanocomposite exhibited superior pseudocapacitive behavior and could be used as an electrode material for supercapacitor applications.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Shuxiang Duan, Ping Li, Hongqiang Zhang, Suping Qu
Summary: Panax ginseng, as an ethnomedicinal plant, has therapeutic effects in traditional medicine. This study investigated the potential use of green-synthesized silver nanoparticles from Panax ginseng leaf extract for the treatment of lung carcinoma and heart protection against mitochondrial dysfunction and cardiac dysfunction in obese insulin-resistant rats. The silver nanoparticles showed spherical morphology with a size range of 12.11 to 43.33 nm. In vivo experiments demonstrated that the silver nanoparticles significantly improved metabolic parameters, heart rate variability, cardiac function, and cardiac mitochondrial function in the rats. This study suggests that silver nanoparticles derived from Panax ginseng have cardioprotective effects.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Maryam Fayazi, Elham Rezvannejad
Summary: In this study, propolis extract was used as a green reductant to deposit silver nanoparticles on sepiolite clay, creating a nanocomposite called Sep/Ag. The nanocomposite was characterized using various techniques, and its ability to adsorb methylene blue (MB) was examined. The results showed that Sep/Ag could efficiently remove MB from solution, and the adsorbent could be regenerated for multiple cycles. This research demonstrates the potential of Sep/Ag nanocomposite as an effective and environmentally friendly sorbent for environmental cleanup.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
M. Sriramraj, A. R. Balu, S. Chitra Devi, B. Sowmiya Devi, M. Suganya, K. Devendran, M. Karthika, S. Adityan
Summary: One-pot green synthesis was used to prepare rGO decorated MgTiO3 perovskite using Solanum trilobatum leaf extract to reduce graphene oxide. The rGO embedded MgTiO3 nanoparticles showed smaller crystallite size, well-defined particle boundaries, increased photodegradation efficiency and antibacterial activity compared to pure MgTiO3.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Zhiliang Guo, Qianheng He, Helin Wang, Changgan Lai, Shuai Ji, Jian Sun, Donghuai Zhang, Liu Nie, Lixu Lei
Summary: Waste plastics are causing serious environmental pollution and there is a pressing need for their recycling. This study presents a novel method to completely degrade waste PET into sodium terephthalate and ethylene glycol through a solid-state reaction at high temperature with minimal solvent. The method offers high efficiency, selectivity, and ease of product separation, making it a promising approach for the recycling economy of other ester-based waste polymers.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Hanan Alhussain, Nuha Y. Elamin, Laila S. Alqarni, Abuzar Albadri, Kamal K. Taha, A. Modwi
Summary: A CaO-TiO2@g-C3N4 sorbent was constructed using sonication method for the elimination of RhB dye from aqueous medium. The sorbent demonstrated equilibrium for the dye adhesion after 120 minutes, with a maximum adsorption capacity of 778.7 mg/g. The nanocomposite showed satisfactory performance in neutral aquatic conditions.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Wei-Dong Liu, Liu-Qing Chen, Qi-Hao Qiu, Ming-Qiang Qi, Han Xu, Chao-Long Chen, La-Sheng Long, Lan-Sun Zheng, Xiang-Jian Kong
Summary: In this study, a mixed valence cerium-oxo cluster was successfully synthesized through low-temperature crystallization, and the coexistence and distribution of Ce ions in different valence states were determined. The mechanism for the generation of +4 valence state was revealed, and the synthesized cluster exhibited strong ultraviolet absorption and long visible light absorption, as well as clear photocurrent response and high photocurrent intensity.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Mahak Dalal, Nidhi Antil, Binesh Kumar, Jai Devi, Sapana Garg
Summary: This research study focuses on the biological efficacy of a newly synthesized Schiff base ligand and its aryltellurium(IV) complexes. The synthesized compounds were characterized using various physical and spectral investigations, and theoretical chemical estimations were also conducted. The results showed that the complexes exhibited mild to strong antimicrobial activity, with higher activity than the Schiff base. Molecular docking experiments revealed the ability of the compounds to bind to receptors. ADMET results indicated favorable drug-like behavior of the synthesized compounds. Overall, these complexes may serve as promising candidates for infection ailments.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Indu Sharma, Ajay Kumar, Jaspreet Kaur, Sanjay Mehra, Arvind Kumar, Suresh Kumar Sharma, Surinder Kumar Mehta, Ramesh Kataria
Summary: Nanozyme based sensors have been developed as an effective method for detecting harmful metal ions in water samples. In this study, a Co(II) based coordination polymer nanoparticle (Co-CP NP) was synthesized and utilized as a nanozyme to detect Fe(II) ions selectively. The Co-CP NP exhibited peroxido-reductase mimicking activity, and the detection limit for Fe(II) ions was found to be 0.66 μM. The catalytic action of the Co-CP NP was further analyzed using Michaelis-Menten kinetics, and the detection mechanism was elucidated through XPS and zeta potential analysis.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Sreenivasulu Venkata Kummari, Vadali Venkata Satya Siva Srikanth
Summary: A simple single-step sonochemical reduction method is used to prepare CoFe2O4-CoFe-reduced graphene oxide (rGO) composites with control of rGO content. The tunable interfacial magnetic proximity-induced magnetization at the interface of CoFe2O4-CoFe and rGO is observed.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Asma Zaka, Muhammad Waqas Iqbal, Amir Muhammad Afzal, Hassabul Hassan, Sarah Alharthi, Mohammed A. Amin, Ahmad M. Saeedi, Hasan B. Albargi, A. Alhadrami, Nawal D. Alqarni, Mohd Zahid Ansari
Summary: The tailoring and rational synthesis of metal-organic framework (MOF) with versatile nano/microarchitectures are of great academic interest due to their promising applications in advanced energy storage devices. A simple and cost-effective hydrothermal method was used to synthesize the carbon nanotubes (CNT) doped Cu-MOF, exhibiting astonishing power and energy density.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)