Article
Cardiac & Cardiovascular Systems
Fan Zhou, Qian Chen, Xiao Luo, Wei Cao, Ziwen Li, Bo Zhang, U. Joseph Schoepf, Callum E. Gill, Lili Guo, Hong Gao, Qingyao Li, Yibing Shi, Tingting Tang, Xiaochen Liu, Honglin Wu, Dongqing Wang, Feng Xu, Dongsheng Jin, Sheng Huang, Haige Li, Changjie Pan, Hongmei Gu, Lixiang Xie, Ximing Wang, Jing Ye, Jianwei Jiang, Hanqing Zhao, Xiangming Fang, Yi Xu, Wei Xing, Xiaohu Li, Xindao Yin, Guang Ming Lu, Long Jiang Zhang
Summary: Coronary artery disease is a leading cause of morbidity and mortality worldwide. Myocardial ischemia can occur in patients with normal or non-obstructive CAD. The combination of coronary CT angiography and CT-FFR may be essential for evaluating and improving outcomes in patients with non-obstructive CAD.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Biotechnology & Applied Microbiology
Gaurav Chandola, Jun-Mei Zhang, Ru-San Tan, Ping Chai, Lynette Teo, John C. Allen, Ris Low, Weimin Huang, Shuang Leng, Jiang Ming Fam, Chee Yang Chin, Ghassan S. Kassab, Adrian Fatt Hoe Low, Swee Yaw Tan, Terrance Chua, Soo Teik Lim, Liang Zhong
Summary: The study assessed the feasibility and accuracy of a non-invasive FFR calculation based on CTCA for predicting coronary hemodynamics before and after stenting, finding a good correlation and agreement with invasive FFR, especially in predicting the hemodynamic effects post-stenting, indicating its potential as a useful tool in PCI planning.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Toshimitsu Tsugu, Kaoru Tanaka, Yuji Nagatomo, Dries Belsack, Hannes Devos, Nico Buls, Bernard Cosyns, Jean-Francois Argacha, Michel De Maeseneer, Johan De Mey
Summary: This study found that in vessels with no apparent CAD, vessel length was the most influential factor on FFRCT, followed by the bifurcation angle.
EUROPEAN RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Yingkai Li, Songyuan He, Zheng Wu, Wenzheng Li, Wen Jian, Zichao Cheng, Cong Wang, Yuchen Shi, Jinghua Liu
Summary: The present study aimed to investigate the relationship between the TyG index and cardiovascular risk in chronic total occlusion (CTO) patients. The study revealed that the TyG index was significantly associated with cardiovascular risk in CTO patients and suggested that it could be a feasible predictor of cardiovascular risk in CTO patients.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zi Yue Zu, Peng Peng Xu, Qian Chen, Yan Chun Chen, Jian Chen Qi, Chun Xiang Tang, Chang Sheng Zhou, Cheng Xu, Xin Jie Sun, Meng Jie Lu, Guang Ming Lu, Yi Ning Wang, Yi Xu, Long Jiang Zhang
Summary: This study investigated the predictive value of CT-derived fractional flow reserve (FFRCT) in predicting anastomosis occlusion after coronary artery bypass graft (CABG) surgery. The results showed that FFRCT≤0.80 was associated with a significant risk reduction of anastomosis occlusion after CABG. Preoperative assessment of hemodynamic significance may improve the CABG surgery strategy and reduce graft failure.
EUROPEAN RADIOLOGY
(2023)
Article
Multidisciplinary Sciences
Zengfa Huang, Beibei Cao, Xinyu Du, Mei Li, Jiong Huang, Zuoqin Li, Jianwei Xiao, Xiang Wang
Summary: We aimed to predict the risk of major adverse cardiovascular events (MACE) in patients with suspected non-obstructive coronary artery disease (CAD) by exploring classifications based on coronary computed tomography angiography (CTA). We compared these classifications with traditional non-obstructive CAD (NOCAD) classification, Duke prognostic NOCAD index, and Non-obstructive coronary artery disease reporting and data system (NOCAD-RADS). 4378 consecutive non-obstructive CAD patients were assessed, and the SPI classification, which focused on proximal involvement of plaques, provided important prognostic information for MACE prediction.
SCIENTIFIC REPORTS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Liu Yang, Peng Peng Xu, U. Joseph Schoepf, Christian Tesche, Balakrishnan Pillai, Rock H. Savage, Chun Xiang Tang, Fan Zhou, Hao Dong Wei, Zhong Qiang Luo, Qing Gen Wang, Chang Sheng Zhou, Meng Jie Lu, Guang Ming Lu, Long Jiang Zhang
Summary: Fractional flow reserve and plaque progression assessed by serial coronary CT angiography predicted the risk of future major adverse cardiovascular events (MACE), demonstrating better accuracy compared to traditional assessment markers.
EUROPEAN RADIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Hankun Yan, Yang Gao, Na Zhao, Wenlei Geng, Zhihui Hou, Yunqiang An, Jie Zhang, Bin Lu
Summary: This study evaluated the diagnostic performance of change in computed tomography-derived fractional flow reserve (CT-FFR) for identifying ischemia lesions. The results showed that CT-FFR and ΔCT-FFR could improve the diagnostic accuracy of ischemia compared to coronary CT angiography (CCTA) alone. Low-attenuation plaque volume and plaque length were identified as independent risk factors for ΔCT-FFR.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xianpeng Wu, Bokai Wu, Wenming He, Xinhong Wang, Kan Wang, Zhengzheng Yan, Zaiheng Cheng, Yuyu Huang, Wei Zhang, Rongliang Chen, Jia Liu, Jian'an Wang, Xinyang Hu
Summary: By expanding the coronary tree in the computational fluid dynamics (CFD) domain, the accuracy of coronary CT angiography (CCTA)-derived fractional flow reserve (FFR) (FFRCT) was significantly improved, leading to a 16.7% increase in sensitivity and the conversion of false-negative cases into true-positive cases. Additionally, the NKS method was able to solve the computational problem efficiently, achieving favorable computational times for future clinical applications.
EUROPEAN RADIOLOGY
(2021)
Article
Medicine, General & Internal
Doo-Hwan Kim, Young-Kug Kim, Tae-Yong Ha, Shin Hwang, Wooil Kim, Hyun-Jung Koo, Dong-Hyun Yang, Joon-Won Kang, Sung-Gyu Lee
Summary: The study evaluated the association between CTCA and long-term MACEs within 5 years after living donor liver transplantation (LDLT), finding that a combination of a coronary artery calcium score (CACS) of >400 and obstructive coronary artery disease (CAD) may be associated with long-term MACEs.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Xiao-long Zhu, Zhi-ying Pang, Wei Jiang, Ting-yu Dong
Summary: This study demonstrates that combining CDI with CT-FFR provides better predictive ability for major adverse cardiac events compared to using CT-FFR alone. Additionally, diabetes and triglyceride levels are also associated with cardiovascular events.
BMC CARDIOVASCULAR DISORDERS
(2022)
Review
Health Care Sciences & Services
Nitesh Gautam, Prachi Saluja, Abdallah Malkawi, Mark G. Rabbat, Mouaz H. Al-Mallah, Gianluca Pontone, Yiye Zhang, Benjamin C. Lee, Subhi J. Al'Aref
Summary: Cardiovascular diseases impose a significant economic burden on healthcare systems worldwide, and artificial intelligence has shown promising applications in the field of coronary artery disease, aiding clinicians in treatment decision-making.
Article
Radiology, Nuclear Medicine & Medical Imaging
Masahiro Hoshino, Seokhun Yang, Tomoyo Sugiyama, Jinlong Zhang, Yoshihisa Kanaji, Rikuta Hamaya, Masao Yamaguchi, Masahiro Hada, Tomoki Horie, Kai Nogami, Hiroki Ueno, Toru Misawa, Taishi Yonetsu, Doyeon Hwang, Joo Myung Lee, Eun-Seok Shin, Joon-Hyung Doh, Chang-Wook Nam, Bon-Kwon Koo, Tetsuo Sasano, Tsunekazu Kakuta
Summary: This study found that the prevalence of coronary microvascular dysfunction (CMD) in patients with intermediate epicardial stenosis is about one-third. CMD was significantly associated with greater lumen volume, fibrofatty and necrotic component volume, and epicardial fat volume.
EUROPEAN RADIOLOGY
(2021)
Article
Mechanics
K. E. Hoque, M. Ferdows, S. Sawall, E. E. Tzirtzilakis, M. A. Xenos
Summary: Computed tomography coronary angiography image-based noninvasive virtual fractional flow reserve (vFFR) is a key factor in diagnosing coronary plaque, with both 1D and 3D hemodynamic factors being used to determine the severity of coronary main arteries lesions. The study shows that the 1D computational results can be used to predict the severity of atherosclerotic plaque in clinical procedures.
Article
Cardiac & Cardiovascular Systems
Cian P. Mccarthy, Sean P. Murphy, Daniel K. Amponsah, Paula K. Rambarat, Claire Lin, Yuxi Liu, Reza Mohebi, Allison Levin, Avanthi Raghavan, Hannah Miksenas, Campbell Rogers, Jason H. Wasfy, Ron Blankstein, Brian Ghoshhajra, Sandeep Hedgire, James L. Januzzi
Summary: This study aimed to evaluate the presence and characteristics of coronary artery disease (CAD) among patients with type 2 myocardial infarction (T2MI). Coronary computed tomography angiography (CTA), fractional flow reserve derived with coronary CTA (FFRCT), and plaque volume analyses were conducted on consecutive eligible individuals with T2MI according to the Fourth Universal Definition of Myocardial Infarction criteria.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)