Article
Cardiac & Cardiovascular Systems
Ralph Stephan von Bardeleben, Philipp Lurz, Paul Sorajja, Tobias Ruf, Joerg Hausleiter, Marta Sitges, Jaqueline Da Rocha e Silva, Michael Naebauer, Marcel Weber, Gilbert H. L. Tang, Megan Heitkemper, Shih-Wa Ying, Jean-Noel Trochu, Saibal T. Kar, Rebecca Hahn, Georg Nickenig, TRILUMINATE Trial Investigators
Summary: Tricuspid transcatheter edge-to-edge repair with the TriClip implant was found to be safe and effective in reducing tricuspid regurgitation and improving clinical outcomes in patients with symptomatic moderate or greater TR at 2-year follow-up.
CIRCULATION-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Thomas J. Stocker, Helene Hertell, Mathias Orban, Daniel Braun, Karl-Philipp Rommel, Tobias Ruf, Geraldine Ong, Michael Nabauer, Simon Deseive, Neil Fam, Ralph S. von Bardeleben, Holger Thiele, Steffen Massberg, Philipp Lurz, Joerg Hausleiter
Summary: TTVR significantly reduced TR severity, improved right atrial v wave, and increased cardiac output. Invasive hemodynamic parameters such as mean pulmonary artery pressure and transpulmonary gradient were significant predictors of 1-year mortality, with pre-capillary pulmonary hypertension patients showing unfavorable prognosis. Invasive hemodynamic assessment may help identify patients who benefit most from TTVR.
JACC-CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Cardiac & Cardiovascular Systems
Mackram F. Eleid, Mohamad Alkhouli, Jeremy J. Thaden, Firas Zahr, Scott Chadderdon, Mayra Guerrero, Guy S. Reeder, Charanjit S. Rihal
Summary: ICE is increasingly used in the early experience of TEER, facilitating leaflet visualization for grasping during the procedure; however, it does not significantly impact the reduction of tricuspid regurgitation compared to using TEE alone.
CIRCULATION-CARDIOVASCULAR INTERVENTIONS
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Rafael Romaguera, Gerard Roura, Alex Ruiz-Majoral, Angel Sanchez-Recalde, Carles Diez-Lopez, Daniel Fontes-Carame, Josep Comin-Colet, Joan A. Gomez-Hospital
Summary: There is supplemental digital content available in the text for reference.
CIRCULATION-HEART FAILURE
(2021)
Article
Cardiac & Cardiovascular Systems
Lukas Stolz, Mathias Orban, Christian Besler, Karl-Patrik Kresoja, Daniel Braun, Philipp Doldi, Martin Orban, Christian Hagl, Karl-Philipp Rommel, Julia Mayerle, Sebastian Hausleiter, Kornelia Loew, Satoshi Higuchi, Mirjam Wild, Matthias Unterhuber, Steffen Massberg, Michael Naebauer, Holger Thiele, Philipp Lurz, Joerg Hausleiter
Summary: This study aimed to evaluate the prevalence and prognostic implications of cardiohepatic syndrome (CHS) in patients with tricuspid regurgitation (TR) treated with tricuspid transcatheter edge-to-edge valve repair (T-TEER). The results showed that CHS was associated with a higher rate of mortality and hospitalization for heart failure (HHF) after T-TEER, and it was identified as an independent predictor of 1-year all-cause mortality. However, T-TEER still led to symptomatic alleviation regardless of the presence of CHS.
JACC-CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Medicine, General & Internal
Myriam Carpenito, Valeria Cammalleri, Luka Vitez, Aurelio De Filippis, Edoardo Nobile, Maria Caterina Bono, Simona Mega, Matjaz Bunc, Francesco Grigioni, Gian Paolo Ussia
Summary: Treatment with the edge-to-edge TriClip device is safe and effective in patients with tricuspid valve regurgitation, resulting in significant reductions in TR grade and improvements in adjacent structures and right ventricular afterload adaptation.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Lucas Burke, Magdi Hassanin, Geraldine Ong, Neil Fam
Summary: Concomitant tricuspid regurgitation is common in patients with mitral regurgitation. Though guidelines recommend repairing both valves during surgery when possible, high-risk patients are often undertreated. Advances in transcatheter edge-to-edge repair have provided new options for managing heart failure.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Cardiac & Cardiovascular Systems
Antonio Mangieri, Alessandro Sticchi, Aisha Gohar, Damiano Regazzoli, Fabio Fazzari, Daniela Pini, Marta Pellegrino, Beniamino Pagliaro, Ferdinando Loiacono, Mauro Chiarito, Bernhard Reimers, Fabien Praz, Azeem Latib, Antonio Colombo
Summary: Tricuspid regurgitation has a negative impact on patient outcomes, and surgical treatment is not suitable for high-risk patients. Percutaneous approaches offer a viable and lower-risk alternative, with several devices currently under development.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Susanne Anna Schlossbauer, Francesco Fulvio Faletra, Vera Lucia Paiocchi, Laura Anna Leo, Giorgio Franciosi, Michela Bonanni, Gianmarco Angelini, Anna Giulia Pavon, Enrico Ferrari, Siew Yen Ho, Rebecca T. Hahn
Summary: This review focuses on the controversial and poorly understood aspects of tricuspid anatomy, including the structure of tricuspid annulus, the variability in number and size of leaflets, and the similarities and differences between tricuspid and mitral valve.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2021)
Review
Cardiac & Cardiovascular Systems
Guillem Muntane-Carol, Alberto Alperi, Laurent Faroux, Elisabeth Bedard, Francois Philippon, Francois Dagenais, Josep Rodes Cabau
Summary: Treatment for severe tricuspid regurgitation (TR) has evolved in recent years, with a shift towards less invasive catheter-based therapies. Transcatheter tricuspid valve intervention (TTVI) procedures have shown high success rates and improved functional status in most patients, although significant residual TR remains a challenge. More long-term data on outcomes beyond 6-12 months are still needed in this field.
CANADIAN JOURNAL OF CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Pedro Luis Cepas-Guillen, Juan Carlos de la Fuente Mancera, Joan Guzman Bofarull, Marta Farrero, Ander Regueiro, Salvatore Brugaletta, Cristina Ibanez, Laura Sanchis, Marta Sitges, Manel Sabate, Xavier Freixa
Summary: Transcatheter tricuspid valve repair (TTVr) with edge-to-edge systems has shown favorable efficacy and safety in treating severe tricuspid regurgitation (TR), improving patients' quality of life and potentially preventing morbidity and mortality associated with TR.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Joerg Hausleiter, Thomas J. Stocker, Marianna Adamo, Nicole Karam, Martin J. Swaans, Fabien Praz
Summary: Mitral regurgitation (MR) is a common valvular heart disease with significant consequences if left untreated. Mitral valve transcatheter edge-to-edge repair (M-TEER) has emerged as an important therapeutic strategy for severe and symptomatic MR.
Article
Cardiac & Cardiovascular Systems
Erwan Donal, Guillaume Leurent, Anne Ganivet, Philip Lurz, Augustin Coisne, Pascal De Groote, Stephane Lafitte, Lionel Leroux, Nicole Karam, Loic Biere, Frederic Rouleau, Catherine Sportouch, Julien Dreyfus, Mohammed Nejjari, Jean-Michel Josselin, Amedeo Anselmi, Elena Galli, Emma Bajeux, Patrice Guerin, Jean-Francois Obadia, Jean-Noel Trochu, Emmanuel Oger
Summary: The Tri.fr trial is a multicentre, randomized controlled study aiming to investigate the impact of non-surgical treatment for tricuspid regurgitation on clinical outcomes. The study will follow 300 patients with severe secondary TR and use the Packer composite clinical endpoint as the primary outcome measure.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Article
Medicine, General & Internal
Clemence Grave, Christophe Tribouilloy, Philippe Tuppin, Alain Weill, Amelie Gabet, Yves Juilliere, Alexandre Cinaud, Valerie Olie
Summary: Mitral regurgitation (MR) is the second most common valvular heart disease in Europe. The burden of mitral valve prolapse (MVP) in hospitals has substantially increased, especially among men.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Nirav Y. Raval, Ali Valika, Philip B. Adamson, Christopher Williams, Marie-Elena Brett, Maria Rosa Costanzo
Summary: Hemodynamic-guided heart failure management is an effective strategy to prevent hospitalization and preserve renal function across severities of comorbid renal insufficiency. This strategy involves remotely obtaining pulmonary artery pressures to guide treatment.
CIRCULATION-HEART FAILURE
(2023)