Article
Cardiac & Cardiovascular Systems
Selena Zhou, Natalia Egorova, Gil Moskowitz, Gennaro Giustino, Gorav Ailawadi, Michael A. Acker, Marc Gillinov, Alan Moskowitz, Annetine Gelijns
Summary: The trend of mitral valve interventions from 2000 to 2016 showed a decrease in mitral valve replacement procedures, an increase in mitral valve repair and MitraClip procedures, with overall improved outcomes despite an increasingly sicker population. Length of stay decreased for all interventions, while comorbidities burden increased. In-hospital mortality also decreased for all interventions, most significantly for MitraClip recipients.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Yaghoub Dabiri, Jiang Yao, Vaikom S. Mahadevan, Daniel Gruber, Rima Arnaout, Wolfgang Gentzsch, Julius M. Guccione, Ghassan S. Kassab
Summary: This study describes the use of artificial intelligence to aid in selecting optimal MitraClip scenarios and generated the necessary MV geometrical data. Results show that the location and number of MitraClips can impact residual mitral regurgitation, and leaflet stresses do not follow a simple pattern.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Medicine, General & Internal
Ayham Daher, Tobias Mueller, Nikolaus Marx, Joerg Schroder, Mohammad Almalla, Andras P. Keszei, Sebastian Reith, Michael Dreher
Summary: The prevalence of sleep disordered breathing is high among patients with mitral regurgitation, even in those without daytime sleepiness. Patients with SDB had significant improvements in respiratory parameters after MitraClip placement, but no significant changes in sleepiness scores were observed.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Cardiac & Cardiovascular Systems
Hidehiro Kaneko, Hiroyuki Kiriyama, Tatsuya Kamon, Hidetaka Itoh, Satoshi Kodera, Katsuhito Fujiu, Masao Daimon, Hiroyuki Morita, Masaru Hatano, Issei Komuro
Summary: Functional mitral regurgitation often accompanies left ventricular dysfunction and has poor clinical outcomes. MitraClip treatment has emerged as a promising therapeutic option, showing potential benefits in reducing heart failure rehospitalization and mortality. Current status and future perspectives of MitraClip for functional mitral regurgitation are discussed in this review.
INTERNATIONAL HEART JOURNAL
(2021)
Review
Cardiac & Cardiovascular Systems
Tanya Salvatore, Fabrizio Ricci, George D. Dangas, Bushra S. Rana, Laura Ceriello, Luca Testa, Mohammed Y. Khanji, Anna Laura Caterino, Corrado Fiore, Antonio Popolo Rubbio, Marianna Appignani, Maria Di Fulvio, Francesco Bedogni, Sabina Gallina, Marco Zimarino
Summary: Secondary mitral regurgitation occurs in patients with heart failure and left ventricular dysfunction, independently associated with poor outcome. MitraClip through percutaneous mitral valve repair is highly effective in reducing MR in HF patients, but the clinical benefit remains controversial.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Zouhair Rahhab, David Scott Lim, Stephen H. Little, Maurizio Taramasso, Shingo Kuwata, Matteo Saccocci, Corrado Tamburino, Carmelo Grasso, Christian Frerker, Theresa Wisst, Ross Garberich, Jorg Hausleiter, Daniel Braun, Eleonora Avenatti, Victoria Delgado, Gian Paolo Ussia, Fausto Castriota, Roberto Nerla, Huseyin Ince, Alper Oner, Rodrigo Estevez-Loureiro, Azeem Latib, Damiano Regazzoli, Nicolo Piazza, Hind Alosaimi, Peter P. T. de Jaegere, Jeroen Bax, Danny Dvir, Francesco Maisano, Paul Sorajja, Michael J. Reardon, Nicolas M. Van Mieghem
Summary: The study evaluated the feasibility and safety of using MitraClip as a treatment option for patients with recurrent MR after failed SMVR, showing that it is a safe and less invasive option. Additional or modified imaging techniques may help overcome technical challenges during leaflet grasping.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Christopher P. Kovach, Sean Bell, Akash Kataruka, Mark Reisman, Creighton Don
Summary: Urgent/emergent transcatheter edge-to-edge mitral valve repair (TMVr) in high-risk patients with acute decompensated heart failure or cardiogenic shock is associated with high short-term mortality and periprocedural complications, indicating the need for prospective studies to inform patient selection and periprocedural management for this intervention.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Cardiac & Cardiovascular Systems
Mikiko Senzai, Satoshi Kainuma, Koichi Toda, Shigeru Miyagawa, Daisuke Yoshioka, Takuji Kawamura, Ai Kawamura, Noriyuki Kashiyama, Yusuke Misumi, Takayoshi Ueno, Toru Kuratani, Tetsuhisa Kitamura, Sho Komukai, Kazuhiro Taniguchi, Yoshiki Sawa
Summary: This study aimed to investigate the incidence and determinants of postoperative adverse events in patients with ischemic cardiomyopathy who underwent long-term durable mitral valve repair. The results showed that approximately 50% of the patients died or were hospitalized for heart failure during the 5-year follow-up, even in the absence of recurrent mitral regurgitation. This finding suggests that durable mitral repair does not always lead to favorable clinical outcomes, and adverse events may be associated with volume overload due to impaired renal function and less favorable pulmonary hemodynamics.
ANNALS OF THORACIC SURGERY
(2022)
Review
Cardiac & Cardiovascular Systems
Eduardo Martinez-Gomez, Angela McInerney, Gabriela Tirado-Conte, Jose Alberto de Agustin, Pilar Jimenez-Quevedo, Andres Escudero, Eduardo Pozo Osinalde, Ana Viana-Tejedor, Josebe Goirigolzarri, Luis Marroquin, David Vivas, Carlos Ferrera, Francisco Noriega, Maria Alejandra Restrepo-Cordoba, Nieves Gonzalo, Javier Escaned, Antonio Fernandez-Ortiz, Ignacio Amat-Santos, Rodrigo Estevez-Loureiro, Carlos Macaya, Luis Nombela-Franco
Summary: The study aimed to evaluate the use of MitraClip device in critically ill patients with significant mitral regurgitation. The results showed that percutaneous mitral valve repair with MitraClip is feasible and effective in reducing MR severity and improving outcomes in high-risk patients. Further prospective trials are needed to confirm these findings and determine the true value of MitraClip in hemodynamically unstable patients.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Cardiac & Cardiovascular Systems
Michael M. Kreusser, Andreas Weber, Nicolas A. Geis, Leonie Grossekettler, Martin J. Volz, Sonja Hamed, Hugo A. Katus, Sven T. Pleger, Norbert Frey, Philip W. Raake
Summary: Percutaneous mitral valve repair (PMVR) via MitraClip implantation is a treatment option for severe mitral regurgitation in advanced heart failure. However, patients with progressive left ventricular dilation may experience recurrent MR after PMVR, leading to the need for re-do MitraClip implantation. The re-do procedure was technically successful in all patients, but procedural success was achieved in only 65% of cases, with a high mortality rate during 12 months follow-up.
Article
Cardiac & Cardiovascular Systems
Michael M. Kreusser, Andreas Weber, Nicolas A. Geis, Leonie Grossekettler, Martin J. Volz, Sonja Hamed, Hugo A. Katus, Sven T. Pleger, Norbert Frey, Philip W. Raake
Summary: This study retrospectively analyzed the characteristics and outcomes of severe HF patients undergoing re-do MitraClip procedure, showing a high technical success rate of 100% but low procedural success rate of 65%, with a high mortality rate during the 12-month follow-up period.
Article
Cardiac & Cardiovascular Systems
Jie Zeng, Qinglan Shu, Cong Lu, Yi Wang
Summary: This report presents a rare case of a 68-year-old Chinese man with nonobstructive hypertrophic cardiomyopathy and severe mitral valve regurgitation treated with transcatheter edge-to-edge repair (TEER), resulting in significant improvement in symptoms.
Review
Medicine, General & Internal
Kaveh Hosseini, Hamidreza Soleimani, Amir Nasrollahizadeh, Yaser Jenab, Angelos Karlas, Dimitrios V. Avgerinos, Alexandros Briasoulis, Toshiki Kuno, Ilias Doulamis, Polydoros N. Kampaktsis
Summary: A comparison of the PASCAL and MitraClip devices showed similar success rates and complication rates for transcatheter edge-to-edge repair (TEER) of the mitral valve. PASCAL was not inferior to MitraClip in reducing the mitral regurgitation (MR) level at discharge.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Amit Iyengar, William L. Patrick, Mark R. Helmers, John J. Kelly, Jason Han, Matthew L. Williams, Emily J. Mackay, Nimesh D. Desai, Marisa Cevasco
Summary: Socioeconomic status has an impact on outcomes after cardiac surgery. This study examined the influence of neighborhood-level socioeconomic status on patients undergoing mitral valve surgery in the United States. It was found that patients from more disadvantaged areas had fewer opportunities for surgery and experienced more postoperative complications.
ANNALS OF THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Livia Trasca, Laura Sanchis, Ander Regueiro, Xavier Freixa, Dragos Vinereanu, Marta Sitges
Summary: The study aimed to assess anatomical changes of the mitral valve apparatus after percutaneous repair with the MitraClip(R) system, and found that the procedure induced stable alterations mainly at the anteroposterior annulus diameter, contributing to reduction of mitral regurgitation.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2021)