Article
Cardiac & Cardiovascular Systems
Tine Prolic Kalinsek, David Zizek
Summary: This case report describes a right-sided approach for LBBAP via the right subclavian vein. By modifying the delivery sheath manually, adequate lead positioning and minimal torque for LBBAP were achieved.
BMC CARDIOVASCULAR DISORDERS
(2022)
Article
Cardiac & Cardiovascular Systems
Pei-Lin Xiao, Cheng Cai, Pei Zhang, Jie Han, Siva K. Mulpuru, Abhishek J. Deshmukh, Yue-Hui Yin, Yong-Mei Cha
Summary: In patients without intrinsic LBBB undergoing CRT, upgrade from pacemaker and AVN ablation were favorable factors in achieving CRT response and better long-term outcomes.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Shengjie Wu, Mengxing Cai, Rujie Zheng, Songjie Wang, Limeng Jiang, Lei Xu, Ruiyu Shi, Fangyi Xiao, Kenneth A. Ellenbogen, Yongmei Cha, Lan Su, Weijian Huang
Summary: This study aimed to assess the benefit of left bundle branch block (LBBB) correction using His-Purkinje conduction system pacing (HPCSP) in atrial fibrillation patients post-AVJ ablation. Results showed that LBBB patients had greater improvement in LVEF and NYHA class function compared to those with narrow QRS duration.
Review
Cardiac & Cardiovascular Systems
Yue Zhang, Yuan Jia, Jia Liu, Rongpin Du
Summary: In this study, the efficacy and safety of His bundle pacing (HBP) and Left bundle branch pacing (LBBP) were compared with right ventricular pacing (RVP) in patients with atrioventricular block (AVB). The results showed that compared to RVP, HBP and LBBP were superior in terms of paced QRS duration and preservation of left ventricular ejection fraction (LVEF). LBBP was associated with a lower pacing threshold and a greater R-wave amplitude compared to HBP, but the stability of pacing output may be a concern.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Oriol Aguilo, Xavier Castells, Oscar Miro, Christian Mueller, Ovidiu Chioncel, Joan Carles Trullas
Summary: This study aimed to conduct a meta-analysis on prospective studies to assess the relationship between bundle branch block (BBB) or wide QRS and the risk of all-cause mortality in patients with acute heart failure (AHF). The findings indicate a significant increase in the risk of all-cause mortality among patients with wide QRS, regardless of the type of BBB (left or right).
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Daniel Rodriguez Munoz, Maria Generosa Crespo-Leiro, Ignacio Fernandez Lozano, Jose Luis Zamorano Gomez, Rafael Peinado Peinado, Luis Manzano Espinosa, Javier de Juan Baguda, Alvaro Marco del Castillo, Fernando Arribas Ynsaurriaga, Rafael Salguero Bodes
Summary: This study aims to explore the long-term benefits and safety profile of heart rate regularization through left-bundle branch pacing (LBBP) and atrioventricular node ablation (AVNA) compared with pharmacological rate-control strategy in patients with heart failure and permanent atrial fibrillation. The study will be conducted from March 2022 to February 2027, with 334 patients enrolled and followed up for a minimum of 36 months. The primary outcome measure is the composite of all-cause mortality, heart failure hospitalization, and worsening heart failure at 36 months.
Review
Cardiac & Cardiovascular Systems
Robert S. Sheldon, Lucy Y. Lei, Monica Solbiati, Derek S. Chew, Satish R. Raj, Giorgio Costantino, Carlos Morillo, Roopinder K. Sandhu
Summary: The aim of this study was to determine the negative predictive value (NPV) of EPS for complete heart block in bundle branch block patients presenting with syncope. The NPV was found to be 0.71, indicating uncertainty in the use of EPS in this population.
Article
Cardiac & Cardiovascular Systems
Gregoire Massoullie, Sylvain Ploux, Geraud Souteyrand, Pierre Mondoly, Bruno Pereira, Nicolas Amabile, Frederic Jean, Didier Irles, Jacques Mansourati, Nicolas Combaret, Alexis Mechulan, Marc Badoz, Antoine Da Costa, Pascal Defaye, Pascal Motreff, Guillaume Clerfond, Pierre Bordachar, Romain Eschalier
Summary: This study aimed to determine the incidence of high-degree atrioventricular block (AVB) after transcatheter aortic valve implantation (TAVI), and evaluate the performance and safety of a risk stratification algorithm based on electrophysiology study (EPS) followed by implantation of a pacemaker or implantable loop recorder (ILR). The study found that new-onset left bundle branch block (LBBB) after TAVI was associated with high rates of high-grade AV conduction disturbances, and the stratification algorithm provided safe and valuable aid to management decisions and reliable guidance on pacemaker implantation.
Article
Cardiac & Cardiovascular Systems
Alexandre Raymond-Paquin, Atul Verma, Jeffrey Kolominsky, Paula Sanchez-Somonte, Enes Elvin Gul, Ajay Pillai, Jordana Kron, Richard Shepard, Gautham Kalahasty, Bernice Tsang, Yaariv Khaykin, Alfredo Pantano, Jayanthi N. Koneru, Kenneth A. Ellenbogen
Summary: This study evaluated the feasibility, safety, and electrophysiological characteristics of left bundle branch area pacing (LBBAP) in patients with atrioventricular (AV) conduction disease. The results showed that LBBAP is safe and feasible with high success rates for patients with AV conduction disease.
Article
Medicine, General & Internal
Justine M. Ravaux, Michele Di Mauro, Kevin Vernooy, Silvia Mariani, Daniele Ronco, Jorik Simons, Arnoud W. Van't Hof, Leo Veenstra, Suzanne Kats, Jos G. Maessen, Roberto Lorusso
Summary: The presence of right bundle branch block (RBBB) significantly increases the risk of post-TAVI permanent pacemaker implantation (PPI), while the impact of left bundle branch block (LBBB) is not significant. This suggests the importance of pre-operative evaluation strategies in patient selection for TAVI.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Javier Ramos Jimenez, Alvaro Marco del Castillo, Daniel Rodriguez Munoz, Luis Borrego Bernabe, Adolfo Fontenla, Maria Lopez Gil
Summary: During surgery, interatrial dissociation and complete block of the sinus impulse to the AV node were observed.
Activation of the AV node became dependent on a subsidiary left atrial rhythm.
Anatomical location of intra and inter-atrial connections must be considered when performing extensive ablation procedures.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Honglei Zhu, Lian Jin, Yanqi Huang, Xiaomei Wu
Summary: This study utilized cardiac modeling and simulation to investigate physiological pacing in clinical settings. By constructing a multiscale rabbit ventricular electrophysiological model, the effects of HBP and LBBP pacing on correcting LBBB were explored, with an emphasis on identifying the optimal pacing timing for improved results.
APPLIED SCIENCES-BASEL
(2021)
Article
Cardiac & Cardiovascular Systems
Xiaofei Li, Junmeng Zhang, Chunguang Qiu, Zhao Wang, Hui Li, Kunjing Pang, Yan Yao, Zhimin Liu, Ruiqin Xie, Yangxin Chen, Yongquan Wu, Xiaohan Fan
Summary: Left bundle branch area pacing (LBBAP) may reduce the risk of heart failure hospitalization or upgrade to biventricular pacing compared to right ventricular pacing (RVP) in patients with atrioventricular block requiring a high burden of ventricular pacing. The difference in clinical outcomes between LBBAP and RVP was mainly observed in patients with high ventricular pacing burden or baseline lower LVEF levels. Independent predictors of the primary outcome included LBBAP, previous myocardial infarction, and baseline LVEF.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Medicine, General & Internal
Zhigang Liu, Xiaoke Liu
Summary: Left bundle branch area pacing enables concomitant atrioventricular node ablation and same-day dismissal, with good pacing parameters and function.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Oren Yagel, Bernard Belhassen, David Planer, Offer Amir, Gabby Elbaz-Greener
Summary: This study aimed to assess the association between the baseline R-wave amplitude in V1 ECG lead and the risk of developing high-degree AVB following new LBBB after TAVR in patients with normal QRS duration. The retrospective study included 117 patients, of whom 14 developed high-degree AVB requiring PPI (Group 1) and 103 did not (Group 2). There were no significant differences in baseline characteristics or procedural parameters between the two groups, but the R-wave amplitude in V1 was smaller in Group 1 compared to Group 2.
